Another year of the Stanford Brain Organogenesis workshop hosted by @brainorganogenesis.bsky.social and @sergiuppasca.bsky.social. My fourth time organizing and teaching it alongside the amazing @rebeccalevymdphd.bsky.social and Sabina Kanton.

I am happy to share our paper uncovering developmental convergence and divergence in autism spectrum disorder (ASD) using human stem cell models. This work was made possible through a wonderful collaboration with Sergiu Pasca’ lab @sergiuppasca.bsky.social and Daniel Geschwind’s lab.

Consider joining us at Stanford as a postdoctoral fellow! If you have a published paper or a preprint, will graduate in the next period, and are excited to work in California, email me your CV and a brief statement of your research interests and trajectory by the end of August.

Grateful to have been part of this work from the Pasca Lab, now published in Nature Biomedical Engineering, on scalable brain organoid production for screening. An early step in a fast-evolving field — and I’m eager to see how things continue to unfold. Story here: www.nature.com/articles/s41...

Scalable production of human cortical organoids using a biocompatible polymer - Nature Biomedical Engineering

Addition of an inexpensive, biocompatible polymer reduces spontaneous fusions of organoids in culture.

nature.com

This week we welcome on campus 2025 class of students for our hands-on Stanford Brain Organogenesis course. With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.

@stanford.edu Stanford Brain Organogenesis Workshop off to a great start with introduction lectures and tissue culture with @sergiuppasca.bsky.social @stanfordbrain.bsky.social

Second day of 2025 Stanford Brain Organogenesis is on full steam! 🚂 @rebeccalevymdphd.bsky.social @sergiuppasca.bsky.social @brainorganogenesis.bsky.social

In @nature.com today we report sensory #assembloids comprising four parts to recapitulate aspects of the pathway that processes pain stimuli and we use it to study genetic syndromes. Work pioneered by the brilliant Ji-il Kim & Kent Imaizumi in close collab with @gregscherrer.bsky.social ! Link 👇

New paper on risk genes for sporadic CJD academic.oup.com/brain/advanc...

Multiomic analyses direct hypotheses for Creutzfeldt-Jakob disease risk genes

Küçükali & Hill et al. integrate GWAS data with transcriptome and proteome-wide association studies to better understand risk factors for sporadic Creu

academic.oup.com

Staff position available in my lab at Stanford! Please share. Details below 👇 careersearch.stanford.edu/jobs/life-sc...

Life Science Research Professional 2 (2 Year Fixed Term) in School of Medicine, Stanford, California, United States

The Stanford Brain Organogenesis Program within the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine is...

careersearch.stanford.edu

Great to see our paper online! Amazing collaboration with Neal over the years, with lots of help from others in the Pasca group.

Sergiu P. Pasca@sergiuppasca.bsky.social · 2y ago

Today we report in 𝘾𝙚𝙡𝙡 𝙎𝙩𝙚𝙢 𝘾𝙚𝙡𝙡 a systematic approach to generate neural #organoids resembling various domains of the neural axis Neal Amin & @kevinkelley.bsky.social developed a multiplexed morphogen screen to generate #organoids that mapped to almost 2/3 of the clusters in the 1st trimester CNS

Deadline approaching fast for our free, hands-on workshop on human stem cell models. This year with a focus on assays & #assembloids for disease modeling. Join us on the beautiful Stanford campus Course organized by the amazing Rebecca Levy and @merveavar.bsky.social!

Applications are open for our Stanford Brain Organogenesis course in 2025! This has gotten more and more competitive and we generally get many hundreds of applications for the 20 or so spots. Please note that the committee gives a lot of attention to the motivation letter!