Medicine by Design

@medicinebydesign.bsky.social

Generating transformative discoveries & accelerating clinical impacts in regenerative medicine and cell & gene therapy in Canada.

James Till, along with his collaborator Ernest McCulloch, laid the groundwork for today's #regenmed researchers through their discovery of stem cells in the 1960s. We are grateful for his work and its enduring impact on the health of all people around the world.

Research at UHN@uhnresearch.ca · last yr.

UHN marks the passing of Dr. James Till, whose work with Dr. Ernest McCulloch first demonstrated the existence of blood-forming stem cells in 1961 at Ontario Cancer Institute, now Princess Margaret Cancer Centre. His work has helped launch the field of #stemcell science.

Congratulations to Clinton Robbins and team! #MedicinebyDesign is proud to be a supporter of this research

University Health Network@uhn.ca · last yr.

Congratulations to Dr. Clinton Robbins and the team at UHN’s Peter Munk Cardiac Centre on their new study published in @nature.com. Their work reveals how cigarette smoke can trigger deadly aortic aneurysms—and points the way to life-saving treatments. Read more: www.nature.com/articles/s41...

Congratulations Ana Andreazza (#UofT and Mito2i) and others on a $23.8-million New Frontiers in Research Fund – Transformation grant: mbd.utoronto.ca/news/mitocho.... #MedicinebyDesign is proud to have helped this research group come together through a Convergent Working Group project.

Mitochondrial transplantation receives $23.8-million New Frontiers in Research Fund grant | Medicine by Design

Powering a revolution in regenerative medicine

mbd.utoronto.ca

A new study published by @pmresearch-uhn.bsky.social's Dr. Steven Chan and team found that a diabetes drug can inhibit the expansion of specific mutant stem cells. Learn how this discovery could reduce blood cancer risks: www.uhnresearch.ca/news/reducin...

Princess Margaret Cancer Centre@pmresearch-uhn.bsky.social · last yr.

Diabetes drug for preventing blood cancer? Our study in @nature.com shows potentials to repurpose metformin to reduce risks of blood cancers & inflammatory illnesses in clonal hematopoiesis patients with DNMT3A(R882) mutations. doi.org/10.1038/s415... @uhnresearch.bsky.social

Work on metformin continues to yield interesting results. Read about the study partially funded by #MedincebyDesign⬇️

Research at UHN@uhnresearch.ca · last yr.

One study from Dr. Steven Chan and his team at @pmresearch-uhn.bsky.social found that a #diabetes drug metformin can prevent expansion of mutant #StemCell clones in clonal hematopoiesis, a condition that can increase blood #cancer risk. Read more ➡️ www.uhnresearch.ca/news/reducin... (2/4)

Congrats to this month’s UHN Honour Roll winners!🎉 🎓 Dr. Gordon Keller – 2025 Achievement Award (ISSCR) 🎓 Princess Margaret Cancer Foundation – Named North American Organization of the Year 🎓 Dr. Eleanor Fish – Recognized by Canada’s Chief Science Advisor Read more: bit.ly/3DHDnxp

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