Paul Knoepfler

@stemcells.bsky.social

Professor at UC Davis studying cancer & stem cell epigenomics. I also do outreach and blog The Niche http://ipscell.com Also stem cell YouTube channel http://cutt.ly/vcsev4J STAT column https://www.statnews.com/category/lab-dish-paul-knoepfler/

📢 We're hiring! We're inviting applications for a tenure-track Assistant Professor position. We seek outstanding scientists with the creativity and vision to build an innovative research program and contribute to our collaborative community. Learn more and apply: recruit.ucdavis.edu/JPF07708

Assistant/Associate Professor- Cell Biology & Human Anatomy

University of California, Davis is hiring. Apply now!

recruit.ucdavis.edu

Trump & Russ Vought proposed a rule to take every federal grant in America hostage. They don't care about making our tax dollars work better—they just want them to work for Trump. Well, Democrats BLOCKED their corrupt rule, and I'll be fighting to kill it permanently.

Mariners trade deadline trades are ho-hum. Probably no real solutions to issues that plague them. Owners don't really give a crud. Just keep doing the same mediocrity, get your profits, and that's it. Compare to the bougie Dodgers. Different universe.

There is little evidence that MAGA influencer Nick Adams’ nonprofit has provided the civics education it claims. A review of the organization's finances show that it has paid Adams and his mother more than half its recent annual revenue.

This MAGA Influencer Runs a Charity to Teach Kids Civics. Much of the Money Goes to Him Instead.

Nick Adams’ Foundation for Liberty and American Greatness has brought in millions in donations and helped him land a State Department appointment, but records show there is almost no indication FLAG w...

propublica.org

Big 2 weeks for FDA AdComs. ICYMI, my take on last week's PCAC mtg on unproven peptides like BPC-157. It was awful, COIs won the day ipscell.com/2026/07/more... You can agree or disagree w/ the AdComs this week but at least they are focused on data, statistics, & patients not profits

More farce or tragedy? What's ahead after RFK Jr.'s PCAC kangaroo meeting green lit risky peptides - The Niche

Biologist describes how RFK Jr.'s kangaroo meeting of PCAC green lights pop peptides no matter despite legit FDA staff concerns.

ipscell.com

GM CEO Mary Barra is introducing Trump at his rally. Something to keep in mind if you're in the market for a vehicle anytime soon.

Any objective views on the whole thing today with the FDA posting pre-mtg documents highly critical of Capricor's HOPE-3 trial and statistical analyses? I'm not sure what to think yet. Here's a STAT piece on this: www.statnews.com/2026/07/27/f...

Ahead of hearing, FDA questions the efficacy of Capricor's Duchenne drug

Ahead of a hearing, the FDA raised questions about the benefits of a Duchenne treatment from Capricor Therapeutics, another twist for the rare disease drug.

statnews.com

ICYMI: Weekly #regenerative reads: new insights into MYC phosphorylation, cool idea that proteins also age and maybe that can be reversed to help the aged, mitochondria don’t like space , &, of course, that conflicted peptide FDA advisory committee ipscell.com/2026/07/week...

Weekly reads: MYC phosphorylation, reverse protein aging, mitochondria don't like space, that peptide committee - The Niche

Professor discusses novel MYC phosphorylation, reverse protein aging, peptide committee mainly gives RFK Jr. what he wants

ipscell.com

Researchers are building computers that run on brain organoids — but have neglected a major ethical issue: People who give tissue samples for biomedical research might have no idea that their cells are being used for biocomputers. www.nature.com/articles/d41...

Researchers are building computers that run on brain organoids — but have neglected a major ethical issue

People who give tissue samples for biomedical research might have no idea that their cells are being used for biocomputers.

nature.com

"Hundreds of clinical trials now show that exercise can significantly reduce symptoms of depression." "Most mental health professionals receive no training in exercise and often default to vague suggestions." bigthink.com/mind-behavio... #Move #MentalHealth

Exercise works for depression. So why isn't it treated like real medicine?

Exercise should be recommended with the same structure and seriousness as medication, argues Nicholas Fabiano, M.D.

bigthink.com