Renae Ryan
@renaeryan.bsky.social
Professor @ University of Sydney; interested in membrane transport proteins, biophysics, pharmacology and diversity and inclusion in STEMM. Views expressed here are my own. She/her.
Seminar alert! We are excited to announce our next CCeMMP Seminar will be with Dr. Rosemary Cater from the Institute for Molecular Bioscience, UQ. Title: Structural and Mechanistic Insights into Nutrient Transport at the Blood Brain Barrier. More info & register: ccemmp.org/events/ccemm...
What an amazing group of people at the 2026 Lorne Protein Meeting. Hope we see many of you there again in 2027!
Yan Jiang is the next Anders session speaker presenting her work on the SLC1A transporter. @lorneproteins.bsky.social
Lorne Proteins 2026 🏖️ Leach Lecturer Carol Robinson, Oxford, on establishing mass spec as a viable technique for structure/function studies; and John Kuriyan, Vanderbilt University, on the structural plasticity and evolutionary potential of DNA clamp loaders. 🔗 Register now: www.lorneproteins.org
Our paper on the human carnitine transporter OCTN2 (SLC22A5) is out in @natcomms.nature.com! We solved structures of OCTN2 in multiple states and explored how carnitine transport is Na⁺-dependent, providing a framework for understanding SPCD disease causing variants and drug interactions.
Structural basis of sodium ion-dependent carnitine transport by OCTN2
Nature Communications - Carnitine uptake by OCTN2 supports fatty acid metabolism. Here, authors report cryo-EM structures of human OCTN2, revealing the mechanism of sodium ion-dependent carnitine...
rdcu.be
Congratulations Parteek Rosie!!!
Dr Rosemary Cater@rosemaryjcater.bsky.social · 8mo agoCongratulations to the Cater Lab's first ever graduate Parteek! Bachelor of Advanced Scince with First Class Honours - we are SO proud of you! Looking forward to another year of fun in the lab together in 2026! 🎓🔬🧪✨
🏖️ 🌊 🤩 Christopher Barnes on molecular characterisation of vulnerable conserved coronavirus antigen:antibody complexes; and Rina Rosenzweig on chaperones recognition and prevention of protein misfolding in neurodegenerative conditions—at Lorne Proteins 2026! 🔗 Register now: www.lorneproteins.org
I am pleased to announce the release of ProteinDJ v2! This is a major update that integrates BindCraft into the pipeline as an alternative to RFdiffusion for binder generation. You can try it out here: github.com/PapenfussLab/proteindj #ProteinDJ #BindCraft #ProteinDesign @wehi-research.bsky.social
🚨 Final Week to Submit Abstracts! This is your last week to be part of Australia’s most iconic protein science meeting. Don’t miss your chance to share your research on the global stage. 👉 Submit now: www.lorneproteins.org #LorneProteins #AbstractsClosing #ProteinScience
🌟 Indigenous Researcher Award Support for indigenous scientists to attend Lorne Proteins through travel and registration bursaries. Learn more and make a difference here 👉 www.lorneproteins.org/conferencesu... #LorneProteins #FutureScientists #ScienceSupport
Are you within 5 years of your PhD? Apply now for the Anders Early Career Award, honouring Professor Robin Anders and recognising excellence in emerging protein scientists. 🎤 Speaking slot + 💰 $500 prize 📅 Apply by Friday 24 October 2025 👉 www.lorneproteins.org #LorneProteins #AndersAward
I am thrilled to release ProteinDJ: a high-performance and modular protein design pipeline. Our open-source workflow incorporates #RFdiffusion, #ProteinMPNN, #FAMPNN, #AlphaFold2 and #Boltz-2. It is a fast, free, and fun way to design proteins (1/5) doi.org/10.1101/2025.09.24.678028 #proteindesign
𝐓𝐡𝐞 𝐀𝐧𝐝𝐞𝐫𝐬 𝐀𝐰𝐚𝐫𝐝 recognises up to 5️⃣ scientists who are within 5 years of their PhD, with a talk secured in a dedicated session! It’s always a highlight of the meeting & a fantastic opportunity to showcase exciting new science 🤩 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐜𝐥𝐨𝐬𝐞 𝟐𝟒 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 𝟐𝟎𝟐𝟓: www.lorneproteins.org/submissions
The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.
A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry
Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...
biorxiv.org
👕✨ Design the next Lorne Protein Conference T-shirt! Entries close 17 Oct – don’t miss your chance to show off your creativity and cement your place in the history of Lorne Proteins 🤓 👉 Submit your design-see the link below... 📢 And don’t forget to submit your abstract by 24 Oct! #LorneProteins
Momentum is building! Join us for the 51st Lorne Proteins Conference Feb 8–12, 2026, Mantra Lorne on the Great Ocean Road, for fun networking activities 🏐 🎾 🥗 🪩 and breathtaking surf-coast accessibility 🏖️ 🏊 🏄 in the generous breaks between sessions! 🔗 Register here: www.lorneproteins.org/register
🥁🥁🥁 The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞 February 8–12, 2026 Register here: www.lorneproteins.org
Microdosing delight to combat stress; interesting concept, backed by neuroscience. Was a pleasure to comment on the very excellent work of @drrachelbarr.bsky.social on how the experience of delight can tune down our stress response. @brainandmindcentre.bsky.social www.smh.com.au/lifestyle/he...
As we stress more than ever, is it time to ‘microdose delight’?
Our brains are not built to handle the daily threats modern humans face. But there’s a trick that may help them.
smh.com.au
Congratulations to the nine researchers and teams placed among the finalists in the 2025 @eurekaprizes.bsky.social 👏 The Prize is among the top science awards in Australia, honouring the calibre of research and innovation, celebrating leaders in their field. Read more: go.sydney.edu.au/2l5jnZ
Beautiful and important work. Congratulations @thamlab.bsky.social and team!
Wai-Hong Tham@thamlab.bsky.social · last yr.Cryo-EM of fertilisation complex Pfs230-Pfs48/45 from malaria parasites! 💕💗 🦟 Transgenic parasites without Pfs230 D13D14 do not transmit 🦙 💉Nanobodies + mRNA induced antibodies reduce transmission New in @Science.org www.science.org/doi/10.1126/... #ScienceResearch #Malaria #WEHI
Happy to report our enzyme found a home! rdcu.be/eaGXG New kid on the block P450 O-demethylase SyoA-the specificity of a monooxygenase with the simplicity of catalysis driven by peroxide. Retrofit your P450 with this active site chemistry today! #lignin #syringol Out today in Nature Communications.
‘We want women to have role models’: how Sydney University is enticing more female academics to engineering
‘We want women to have role models’: how Sydney University is enticing more female academics to engineering
A mass recruitment campaign with roles reserved solely for women has been launched at a faculty where fewer than one in five academics are female * Get our breaking news email, free app or daily news podcast When Dr Jacqueline Thomas started her academic career in civil engineering a decade ago, she was one of just two full-time women in the school. Thomas had returned to Australia after a stint in Africa to teach a new humanitarian engineering major at the University of Sydney, the first of its kind in the country. “It was crazy, it really took me by surprise,” she said. “When I started, I just thought, ‘great, I got the job, perfect’. And then I realised.” Continue reading...
theguardian.com
Our article showing energy production from air alone is in PNAS today. This paper provides an ultimate biochemical proof that microbes can survive simply by 'making' energy from air (making two ATP per molecule atmospheric H2 consumed) and has biotech applications. www.pnas.org/doi/10.1073/...
ATP synthesis driven by atmospheric hydrogen concentrations | PNAS
All cells require a continuous supply of the universal energy currency, adenosine triphosphate (ATP), to drive countless cellular reactions. The un...
pnas.org
We are excited to share our EVENTS for #BlackInBiophysicsWeek 2025!!! We will be host #BIBPSWeek from Monday, 5/26 to Friday 5/30. RT and help us spread the word! A thread of Events below #BIBPS25 #BlackInBiophysics @biophysicalsoc.bsky.social @blackinx.bsky.social
CCeMMP Seminar alert⏰ We welcome Professor Juan Du, Department of Molecular Biosciences, Northwestern University, Illinois, USA! “The importance of Physiological Temperature in Biomedical & Biophysical Research” More details and register: ccemmp.org/events/ccemm...
World-first: researchers have discovered what protein #PINK1 looks like in humans and how it is activated, solving a decades-long mystery in the fight against #Parkinsonsdisease. The team hope to use the knowledge to find a drug to stop #Parkinsons. www.wehi.edu.au/news/scienti...
Scientists solve decades-long Parkinson’s mystery
WEHI researchers have made a huge leap forward in the fight against Parkinson’s disease, solving a decades-long mystery that paves the way for development of new drugs to treat the condition.
wehi.edu.au
More than 2 decades ago the PINK1 protein was found to be linked to Parkinson's disease, but its structure and how it was activated was not known. Until @science.org today. A triumph for cryo-EM and structural biology, introducing new targets for drug intervention. www.science.org/doi/10.1126/...
Celebrating Women in Science! 👏 As we prepare for #IWD2025, we're excited to spotlight the brilliant women in our centre!🥳Stay tuned for heartfelt nominations from their colleagues, celebrating their achievements and impact. We’re proud to feature them in this special series! #AccelerateAction
In this time of chaos - something good! We are excited to share our final (or near final) speaker list for the 3rd UCSF Full Circle Symposium 4/3-4/4 to highlight Native biologists! Please share the word and register to attend the webinar in person! More info: qbi.ucsf.edu/full-circle-...
