The Power of Expectations
@sfb-trr-289.bsky.social
SFB/TRR 289, a transregional collaborative research center on the role of patients’ treatment expectations Joint work of @unidue.bsky.social, @uni-hamburg.de & @unimarburg.bsky.social Speaker @ulrikebingel.bsky.social https://treatment-expectation.de
Shout-out to @torwager.bsky.social and the CAN Lab, who created this amazing resource for all #placebo researchers! 💊 Check it out: scienceofplacebo.org
tor@torwager.bsky.social · 3w agoLaunching scienceofplacebo.org: a living bibliography of placebo and nocebo research. New papers screened & tagged daily by design, population, outcome and findings, with a searchable database (currently about 5,000 papers), an interactive researcher map, events, news and discussion.
⏰ New preprint ⏰ Our PhD student Jialin Li (@jialinli02.bsky.social) developed the PAin and RElief Signature (PARES), a multivariate brain signature trained to predict bidirectional changes in pain perception! ⬆️⬇️ Read the work here: www.biorxiv.org/content/bior...
We’re looking for a PhD researcher in high-resolution laminar fMRI! 🔬 Laminar fMRI of Hippocampus 🌍 International, interdisciplinary team 📍 Essen, Germany | 4-year PhD position | 75% part-time ℹ️ Subject to the approval of the funder 👉 Apply by 30 September 2026: www.uni-due.de/karriere/ste...
Penguin's Job Application
Alt: Penguin repeatedly hits a sign labelled “Job Application”.
static.klipy.com
A new (German) podcast episode has been added to ut podcast playlist, this time by @helenahartmann.com who was a guest in "Stille Regie" and talks about placebos, pain, and the subconscious 🤩 open.spotify.com/episode/3G19...
#25 Placebo, Schmerz und das Unterbewusstsein - Interview mit Dr. Helena Hartmann
Stille Regie - der Podcast über das Unterbewusstsein · Episode
open.spotify.com
The Power of Expectations@sfb-trr-289.bsky.social · 7mo agoInterested in finding out more about the topics of #treatmentexpectation and #placebo/#nocebo effects? 🤔 🔊 We collected all podcasts episodes featuring members of our CRC! 🎤 Browse all episodes here ➡️ open.spotify.com/playlist/2no...
Great work on the influence of warmth and competence of doctors on patient understanding and the patient-doctor-relationship! 😍
Tobias Kube@tobikube.bsky.social · 2w agoNew article with @a-seewald.bsky.social: We show that patients' responses to normal diagnostic test results critically depend on the doctor's behaviour. If they are warm and competent, patients can take in such information much better and have less desire to consult other doctors or have more tests.
In case you missed it, we have a bilingual video series called 🥜 "In a nutshell" 🥜 In this series, our scientists explain what their work has to do with expectations, what new research found, & what patients can do to feel better. Here they are all in a thread for you to browse & watch! ⤵️
Jason Bateman: In A Nutshell
ALT: Jason Bateman: In A Nutshell
static.klipy.com
How can we leverage expectation effects to improve outcomes in the context of digital mental health interventions? Read about it here: doi.org/10.1016/j.in...
😖 Chronische Schmerzen? 😖 Dann suchen wir dich für unsere neue #Onlinestudie (Dauer: 30 min, Aufwandsentschädigung 15 Euro)! 🤩 Hilf uns herauszufinden, wie chronische Schmerzen das Denken, Fühlen und Handeln beeinflussen. 🤔 ▶️ Zum Fragebogen: tinyurl.com/Online-Schme...
Great work from our affiliated project AF05 led by @tobikube.bsky.social! 🌟 Positive framing (the likelihood of NOT HAVING a disease) reduces perceived risk & emotional concern to normal diagnostic test results. It also reduces intentions for follow-up consultations & further tests.
Are you from the Essen area and interested in writing your medical dissertation in the field of pain research? Then we're looking for you! 😀 "Layers of Pain" is a super cool project based at the @elh-institute.bsky.social using 7T neuroimaging techniqes! 🧲🧠
Great and important paper ( @sfb-trr-289.bsky.social )! On one hand surprising on the other hand, I guess the meta-meta nature of the analysis really hides the specific differences between settings (as the authors acknowledge) www.jclinepi.com/article/S089...
Impact of active placebo controls on estimated drug effects in randomized trials: a meta-epidemiological study
Our objectives were, first, to assess the impact of active placebo vs standard placebo control interventions on estimated benefits of experimental interventions in pharmacological randomized clinical ...
jclinepi.com
Here are some impressions from the Essen #GlobalWalkAgainstPain, held in the remarkable surroundings of the UNESCO World Heritage Site Zeche Zollverein. Together, we raised awareness of what it means to live with pain — and of the challenges we still face in understanding and treating it.
😍 New work from A18 😍 We found that optimizing expectations leads to enhanced efficacy of a mindfulness‐based intervention in individuals with low‐baseline expectations! Read the publication in the Journal of Clinical Psychology here: doi.org/10.1002/jclp...
Optimizing Expectations Leads to Enhanced Efficacy of a Mindfulness‐Based Intervention in Individuals With Low‐Baseline Expectations: A Randomized Controlled Trial
Introduction Treatment expectations for medical and psychological treatments and positive patient-provider interactions are critical mechanisms driving the placebo effect and may augment an interven...
doi.org
New opinion paper in @cp-trendsneuro.bsky.social led by Katja Wiech and @ulrikebingel.bsky.social! ▶️ Beyond Bayesian integration: how meaning shapes placebo effects Read the paper: www.sciencedirect.com/science/arti...
Today is the last Meet the Scientist event aboard the #MSWissenschaft and one of our emerging PIs, Marcel Wilhelm from @unimarburg.bsky.social, is there to answer all of your questions! ✨ 10:00-15:00 in Mainz! ms-wissenschaft.de/de/veranstal... @w-i-d.de
German publication from A13 PI Regine Klinger on treatment expectations in the perioperative setting! www.thieme-connect.com/products/ejo...
👥 Today is meeting day 👥 The overarching projects explained new developments over the 2nd funding period, especially regarding data sharing, psychometrics, and involvement of our patient advisory board! Z02: treatment-expectation.de/projekte-peo... Z03: treatment-expectation.de/projekte-peo...
🫵⏳⚡Haben Sie chronische Schmerzen? 💻❓Im Rahmen eines Forschungsprojekts am Universitätsklinikum Essen suchen wir Personen mit chronischen Schmerzen jeder Art für die Teilnahme an einer kurzen Online-Fragebogenstudie. 1/3
Is 10% the same as 1 in 10? It is not, our results suggest, at least not in terms of how people respond to such likelihoods when it comes to medical diagnostic information. Results speak to the importance of thoughtful likelihood framing in clinical practice. www.sciencedirect.com/science/arti....
When ‘unlikely’ is not the same as ‘likely not’: Effects of likelihood framing and numerical format on patients’ responses to normal diagnostic test results
Communicating the results of diagnostic testing is a central task in clinical practice. Even when results are normal, patients may remain concerned, p…
sciencedirect.com
In a rare occasion, nearly all of our science comunication team members came together in one virtual room to discuss next steps! 😍 #scicomm rocks! ⭐ @ulrikebingel.bsky.social @helenahartmann.com
As #pain researchers, we are happy to participate in the Global Walk Against Pain on August 29th to raise awareness of chronic pain! 💪 More info about the walk: walkagainstpain.org @ulrikebingel.bsky.social @neurologieessen.bsky.social @unidue.bsky.social @elh-institute.bsky.social
amazing, international team effort led by ECRs from our CRC and worldwide!!
The Power of Expectations@sfb-trr-289.bsky.social · last mo.This paper was led by CRC members @helenahartmann.com, Diana Müßgens & @aulenkamp.bsky.social, who were joined by many other members of @sipsplacebo.bsky.social! 😍 @julkleibo.bsky.social @katschmidt25.bsky.social @liviaasan.bsky.social @sheddenmora.bsky.social @ulrikebingel.bsky.social & more!
⭐ New work from our early career researchers!⭐ In this review, we outline methodological considerations for designing and conducting #openlabelplacebo studies in #pain research and beyond - with direct experience in conducting such studies from each author. Read the paper: doi.org/10.1097/j.pa...
😖 Chronische Schmerzen? 😖 Dann suchen wir dich für unsere neue #Onlinestudie (Dauer: 30 min, Aufwandsentschädigung 15 Euro)! 🤩 Hilf uns herauszufinden, wie chronische Schmerzen das Denken, Fühlen und Handeln beeinflussen. 🤔 ▶️ Zum Fragebogen: tinyurl.com/Online-Schme...
While I'm not a big imaging guy I think this is a really useful and interesting analysis. Might be a bit biased as this work is led by fellow @sfb-trr-289.bsky.social members. Congrats to the team! www.nature.com/articles/s41...
Meta-analytic evidence for distinct neural correlates of conditioned versus verbally induced placebo analgesia - Nature Communications
Placebo analgesia shows that expectations induced by suggestions or conditioning can reduce pain without active treatment. Here, the authors conduct an individual-level meta-analysis of 16 studies and...
nature.com
Important work led by one of our PIs, @sheddenmora.bsky.social! 🤩 This study investigated psychological determinants of pregnancy-related symptom burden in 347 women. Read it here: doi.org/10.1038/s415...
Expectations predict early pregnancy-related symptom burden - Scientific Reports
Scientific Reports - Expectations predict early pregnancy-related symptom burden
doi.org
⏰ New preprint ⏰ "Layer-specific cortical processing dissociates sensory and cognitive influences on pain" www.biorxiv.org/content/10.6... Collab w. @elh-institute.bsky.social, @tspisak.bsky.social, @ulrikebingel.bsky.social and some people not on here 😍
All the details are in the thread, just wanted to say this is really cool work. @sirileknes.bsky.social discussed some her work for a @sfb-trr-289.bsky.social webinar which was fantastic as well ( youtu.be/rRQb2NhDs60?...) bsky.app/profile/siri...
Webinar: Siri Leknes - When and how opioids fail to meet expectations
YouTube video by Die Macht der Erwartungen
youtu.be
Siri Leknes@sirileknes.bsky.social · 2mo agoMajor paper out: A heroic* demonstration that even acute stress increases drug intake in healthy people *4-session 2x2 RCT with ~4 oxycodone injections in 66 volunteers - with repeated blinded 2-panel stress/control inductions (ReSST) 1/🧵 www.nature.com/articles/s44...