Lucas Rebiffé

@lucasrebiffe.bsky.social

PhD Candidate at IGFL in Leulier Lab working on nutrition, intestine and microbiota | Lecturer at ENS of Lyon #GutPhysiology #Microbiota #| He/Him

Very happy to share this story, where we explored the interaction between GLP-1 signalling and growth! ⬇️ Besides being of scientific interest, it is my very first paper, stepping into the world of physiology ✨

Filipe De Vadder@filipedevadder.bsky.social · 10mo ago

Our new study, just accepted in the Journal of the Endocrine Society 👉 doi.org/10.1210/jend... We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.

1/ 🚨 Excited to share our new study, now published in The Journal of Nutrition! We developed a mouse model of juvenile protein-energy malnutrition (PEM) to assess growth recovery after refeeding with optimal or suboptimal diets. 🧵 www.sciencedirect.com/science/arti...

Suboptimal refeeding compensates stunting in a mouse model of juvenile malnutrition

Early postnatal life is a critical period of rapid growth in mammals, heavily reliant on adequate nutrition. Protein-energy malnutrition (PEM) during …

sciencedirect.com