This was a deeply collaborative effort. Barbara Rentroia-Pacheco with @sharmaharsh.bsky.social, Lara Pozza, Joleen Traets, @bishaltandukar.bsky.social , Olivia Steijlen, Romy Ruiter, Noel Cruz-Pacheco, Daphne Huigh, Arne Van Hoeck, Yan-Ting Chen, Beatriz Infante, Defne Baskurt, Vignesh Arunachalam,

☕ @shainlab.bsky.social , @bishaltandukar.bsky.social & co dissect the mutational, gene expression and morphological features of adult human skin melanocytes at single-cell resolution. bit.ly/4wzMyX0

Somatic mutations distinguish melanocyte subpopulations in human skin - Nature Cell Biology

Tandukar et al. dissect the mutational, gene expression and morphological features of adult human skin melanocytes at single-cell resolution.

bit.ly

Excited to share our latest work from @shainlab.bsky.social lab, now out in Nature Cell Biology: “Somatic mutations distinguish melanocyte subpopulations in human skin.” We find evidence that melanocyte stem cell dynamics shape human skin homeostasis and UV response. www.nature.com/articles/s41...

Great to see research on tanning bed and cancer risk from @bishaltandukar.bsky.social @shainlab.bsky.social on today’s @ucsanfrancisco.bsky.social Town Hall www.ucsf.edu/news/2025/12... #UCSFCancerProud

“We found that tanning bed users in their 30s and 40s had even more mutations than people in the general population who were in their 70s and 80s” @bishaltandukar.bsky.social @shainlab.bsky.social on latest study from @ucsanfrancisco.bsky.social & Northwestern Univ cancer.ucsf.edu/news/2025/12...

Thank you to @bishaltandukar.bsky.social and Pedram Gerami (co-first authors) and the many others who contributed. @delahnydeivendran.bsky.social @sharmaharsh.bsky.social among many others not on Blue Sky

I am thrilled to share the latest manuscript from the Shain lab, describing the genetic changes that transform a keratinocyte into cutaneous squamous cell carcinoma (and everything in between). www.nature.com/articles/s41...

Special thanks to @bishaltandukar.bsky.social for leading this work and to fantastic collaborators, Robert Judson-Torres and Iwei Yeh

Thanks to funders. NCIHTAN , NIH_NCI, cdMRP, NIH_NIAMS @melanomaresearch.bsky.social, LEOFondet, @utah.edu, @ucsfcancer.bsky.social

Also thanks to other authors… Delahny Deivendran, Aravind K Bandari, Rojina Nekoonam, Limin Chen, Neda Bahrani, @harshsharma-cb.bsky.social, Beatrice Weier, Noel Cruz Pacheco, Min Hu, Kayla Marks, Rebecca Zitnay