🚨review paper alert: non-invasive prenatal screening (NIPS) traditionally predicts common trisomies. NIPS data however also contains genetic signal to predict additional complications: malignancies, rare autosomal trisomies confined to the placenta, monogenic disorders and common genetic risks.

Expanding the scope of non-invasive prenatal screening

Nature Genetics - Cell-free DNA from non-invasive prenatal screening reflects the maternal and fetal genome and epigenome. This Review discusses its analysis for actionable pregnancy complication...

rdcu.be

Methods and applications for single-cell and spatial multi-omics go.nature.com/3GkzmzZ #Review by Katy Vandereyken, Alejandro Sifrim, @bernthie.bsky.social & Thierry Voet Free to read here: rdcu.be/c6JjL

Methods and applications for single-cell and spatial multi-omics

Nature Reviews Genetics - In this Review, the authors discuss the latest advances in profiling multiple molecular modalities from single cells, including genomic, transcriptomic, epigenomic and...

rdcu.be

Honoured to see an article about my research on extra-pair paternity in @science.org. Many thanks to journalist @spoke32.bsky.social for the story and to all colleagues for their quotes! Hopefully, future visitors to my office will be less surprised by a (reproduction) 17th-century painting...

How often are children genetically unrelated to their presumed fathers?

Tackling a touchy subject, genetic detective finds only 1% of European children have unexpected paternity

science.org

🚨The final deadline to register for #RNGS25 is this Wednesday, March 5th!🚨 Make sure to register - You don’t want to miss Prof. Bernard Thienpont (@bernthie.bsky.social)'s fascinating talk on improving patient care by using cell-free DNA methylome analysis.🧬 www.vibconferences.be/events/revol...

Review alert - "Modelling and design of transcriptional enhancers" by Seppe and Vasilis 👇

Seppe De Winter@seppedewinter.bsky.social · 2y ago

We wrote a review article on modelling and design of transcriptional enhancers using sequence-to-function models. From conventional machine learning methods to CNNs and using models as oracles/generative AI for synthetic enhancer design! @natrevbioeng.bsky.social www.nature.com/articles/s44...

📢 #JobAlert We are looking for a lab technician. You can contribute to various interesting research projects. Apply before 11/03: kuleuven.be/personeel/jo...

Laboratoriumtechnoloog (Lab technician)

Een gevarieerde functie in een boeiende onderzoeksomgeving!

kuleuven.be

In the most recent episode we talked with @vonmeyennlab.bsky.social from ETH Zürich about his work on the interplay of nutrition, metabolic pathways, and epigenetic regulation. #podcast #epigenetics #chromatin Listen here: https://buff.ly/4jmwK3j

Delighted to share our 'Androgen clock' paper in #PNAS ow.ly/Guts50ULghF - the first way to predict long-term androgen exposure using DNA alone. We so much more than the sequence we are born with! Stellar work (and animation - SOUND ON) by Dr Victoria Sugrue youtu.be/GL55yjMalII

Predicting ‘male-time’ with the Androgen Clock

YouTube video by Epigenetics Otago

youtu.be

Finding new folks to follow: try out this tool. bsky-follow-finder.theo.io

🧬Today is your last chance to submit your research for #RNGS25, the leading European #sequencing conference. Present your work on stage or during the poster sessions. Submit it before midnight (CET) tonight here: vibbio.tech/40g5N8P #NGS #multiomics #genomics #epigenomics

very elegant approach to in vivo CRISPR screens!

Ulrich Elling@ulielling.bsky.social · 2y ago

Today we published a new paradigm to do CRISPR screens in complex model systems such as in vivo but also e.g. in organoids. The publication came out in Nature Biotechnology. 1/ www.nature.com/articles/s41...

Looking forward to meeting you all in Antwerp!

VIB Training & Conferences@vibtrainconf.bsky.social · 2y ago

Are you active in #sequencing and want to show your research to leading researchers? Submit an abstract for #RNGS25: vibbio.tech/4iJMnS0 Present on stage with a poster pitch or during the poster sessions. The abstract deadline is 15 January 2025. #ngs #genomics #multiomics #epigenomics #AI #ML

Are you active in #sequencing and want to show your research to leading researchers? Submit an abstract for #RNGS25: vibbio.tech/4iJMnS0 Present on stage with a poster pitch or during the poster sessions. The abstract deadline is 15 January 2025. #ngs #genomics #multiomics #epigenomics #AI #ML