André Schneider, University of Bern
@schneian.bsky.social
Biochemist interested in mitochondria, trypanosomes and science in general
Nosey Darner! I think this is a Southern Hawker which was flying in quite a dark background over some still water. Canon R5 and Sigma 500mm f4 sport (great lens) SS1/1600 F6.3 ISO2000 #dragonfly #insect #macro #entomology #bugs
Only ~238,000 base pairs (DNA sequence length). That's about 60K bytes worth of information. Biology is cool and sometimes even efficient 😉
A hidden archaeal lineage with an ultra-reduced genome retaining only its replicative core
Harada et al. describe an archaeon, recovered from a single marine plankton cell, whose 238-kb genome is the smallest known for the domain. It has lost nearly all metabolism but keeps the machinery to...
share.google
Also worth mentioning, the only DNA preparation good enough for this type of analyses at that time cam from the lab of Rudolf Signer of the University of Bern.
Exclusive: A new analysis refutes James Watson’s claim that he was the first to recognize the significance of the famed photograph 51. https://scim.ag/4rTKck8
Superidee gut umgesetzt
Wie gut kennt ihr euch mit Ländern und Flaggen aus? Das ist zwar völlig unnützes Wissen, aber ich habe am Wochenende ein völlig unnützes Spiel gebastelt, mit dem man das feiern kann. Wer schafft den Highscore? www.florianaigner.at/grenzgenial/
How are mitochondrial transcription and DNA replication coordinated in Trypanosoma brucei? Torsten Ochsenreiter &co identify mtTF1, the first mitochondrial #TranscriptionFactor in Kinetoplastea required for #GeneExpression and maxicircle replication.🧪 buff.ly/ZhYVzts
Timing can be important (I was surprised this worked so well, considering it's an iphone and no real camera)
Sometimes you need a helping hand
A medieval #ship was reused as basement ceiling in Konstanz (Southern Germany), it reveals rare clues medieval shipbuilding at Lake Constance. archaeologymag.com/2026/08/medi...
After a quite medical talk on human cell lines I was attending, somebody was asking the question: What is the relevance for C. elegans?
- All studies on fruit flies can be extrapolated to humans. But we don't give a damn ! - We become scientists to understand the world, not to cure a insignificant, conspecific, primate. - (The playful mindset of research). www.psypost.org/disrupting-s...
Good review by @philipcball.bsky.social of Farmelo’s new biography of Stephen Hawking. In talking to old Cambridge folk for my Crick biography, I was surprised at the animosity some expressed towards Hawking. This shows why.
Hawking by Graham Farmelo review – the dark side of genius
A biography of the physicist recognises his achievements, but also reveals the selfish narcissist underneath
theguardian.com
A single amino acid can determine the stability of an entire protein machinery - check out this new publication by SFB 1381 PIs Nora Vögtle and Pitter Huesgen, revealing how precise protein trimming by ICP55 safeguards mitochondrial protein complexes. doi.org/10.1038/s415...
A single-amino-acid cleavage controls global mitochondrial complex integrity - Nature Structural & Molecular Biology
Kücükköse, Luzarowski and colleagues show that removing a single N-terminal amino acid during the maturation of newly imported mitochondrial proteins globally stabilizes mitochondrial protein complexe...
doi.org
- Suppose that: Life started two times & Bacteria and archaea probably appeared independently of the, not yet alive, LUCA (organic matter plus rock) www.science.org/doi/10.1126/...
Intermediate stages in the origin of metabolism at a phosphorylating hydrothermal vent
Enzymatic metabolism emerged from metal-catalyzed, aqueous reactions of H2, CO2, NH3 and phosphite at a hydrothermal vent.
science.org
🧵🚨: Remember the recent #genAI cheating scandal at Brown? Everyone talks about the average score drop from take-home midterm to proctored final: 95.7 → 48.8. That number alone can't settle anything. But the released data can, and almost nobody has looked at it. So we did! Read on. #AcademicSky
What exam scores can and cannot prove about unauthorized AI assistance: Evidence from a highly public classroom episode
In spring 2026, an economics professor at Brown University gave a take-home midterm and, after unusually high scores, made the final exam proctored. Among the 59 students who completed the course, ave...
arxiv.org
T. brucei KMP11 is tiny, essential, and its function is unknown. Here we show that it localizes to the FAZ/TAC/PFR/MtQ but not to the BB, suggesting that KMP11 may X-link alpha-helical cytoskeletal proteins. Congrats to Salome, Torsten et al. journals.biologists.com/jcs/article-...
journals.biologists.com
Sure, let's engineer cockroaches to make them MORE indestructible
Remote-controlled cyborg cockroaches can now breathe underwater for up to 3 hours thanks to tiny SCUBA suits. Researchers hope one day they could even help us to explore space or planets like Mars. www.newscientist.com/article/2531...
Rosetta stone for “The extended central dogma of Mol Biol”. Bottom: b-globin 🧬. Middle: b-globin protein🩸. Top: cell types and organs 🫁 ❤️🧠. We understand the gene to protein transition, we are still working out how cell types are formed. Easteregg at the bottom for @matthewcobb.bsky.social #SciArt
Beautiful videos nicely explaining microtubules! Congratulations to Renaud Chabrier and Casten Janke 👍 www.youtube.com/watch?v=dVbv...
Microtubules | Scientific Animated Short Film 2026
YouTube video by Drawing Intelligence
youtube.com
A new retraction for an influential evolutionary biologist is raising the question of whether scientific misconduct more than 20 years ago was just a blip in his impressive publication record or further proof, as some claim, that much of his work rests on a shaky foundation.
A prolific evolutionary biologist caught faking data decades ago notches a new retraction
A study claiming a tenfold decrease in bugs splattered on evolutionary biologist Anders Møller’s windshield over two decades has been retracted. shanecotee / iStock Anders Møller, an influential ev…
retractionwatch.com
My nine year old asked for a Rosetta Stone cake for his birthday
Philipp Rieche, Marten Exterkate, Arnold Driessen et al show that the #lipid divide between #bacteria and #archaea is not as strict as previously thought as bacterial lipid synthesizing enzymes can use both stereo-forms of glycerol-phosphate. #MembraneBiology -> link.springer.com/article/10.1...
Bacterial lipid synthesizing enzymes PlsY and PlsC utilize both stereo-forms of glycerol-phosphate - EMBO Reports
The chemical composition of membrane lipids differs between eukarya, bacteria and archaea. The central dogma posits that the stereochemistry of phospholipids in bacteria is distinct from archaea. Bact...
link.springer.com
Today marks 30 years since we identified the apicoplast, a relict plastid in human and animal parasites (PMID 8632819). Apicoplasts are the target of the widely used antimalarial prophylactic doxycycline, which has saved many thousands of malaria infections.