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André Schneider, University of Bern

@schneian.bsky.social

Biochemist interested in mitochondria, trypanosomes and science in general

45 Posts234 Follower178 Folgt
Chad Topaz Queer DEI Race Traitor@chadtopaz.bsky.social · 6d ago

🧵🚨: Remember the recent #genAI cheating scandal at Brown? Everyone talks about the average score drop from take-home midterm to proctored final: 95.7 → 48.8. That number alone can't settle anything. But the released data can, and almost nobody has looked at it. So we did! Read on. #AcademicSky

What exam scores can and cannot prove about unauthorized AI assistance: Evidence from a highly public classroom episode

In spring 2026, an economics professor at Brown University gave a take-home midterm and, after unusually high scores, made the final exam proctored. Among the 59 students who completed the course, ave...

arxiv.org

Retraction Watch@retractionwatch.com · last mo.

A new retraction for an influential evolutionary biologist is raising the question of whether scientific misconduct more than 20 years ago was just a blip in his impressive publication record or further proof, as some claim, that much of his work rests on a shaky foundation.

A prolific evolutionary biologist caught faking data decades ago notches a new retraction

A study claiming a tenfold decrease in bugs splattered on evolutionary biologist Anders Møller’s windshield over two decades has been retracted. shanecotee / iStock Anders Møller, an influential ev…

retractionwatch.com

EMBO Reports@emboreports.org · 2mo ago

Philipp Rieche, Marten Exterkate, Arnold Driessen et al show that the #lipid divide between #bacteria and #archaea is not as strict as previously thought as bacterial lipid synthesizing enzymes can use both stereo-forms of glycerol-phosphate. #MembraneBiology -> link.springer.com/article/10.1...

Bacterial lipid synthesizing enzymes PlsY and PlsC utilize both stereo-forms of glycerol-phosphate - EMBO Reports

The chemical composition of membrane lipids differs between eukarya, bacteria and archaea. The central dogma posits that the stereochemistry of phospholipids in bacteria is distinct from archaea. Bact...

link.springer.com

Geoff McFadden@fad1.bsky.social · 2mo ago

Today marks 30 years since we identified the apicoplast, a relict plastid in human and animal parasites (PMID 8632819). Apicoplasts are the target of the widely used antimalarial prophylactic doxycycline, which has saved many thousands of malaria infections.

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Dirk-Jan Scheffers 🟥@dirkscheffers.bsky.social · 2mo ago

Briefly, we used two fluorescent dyes that were supposed to label newly synthesized cell wall material in bacteria, but found that when we blocked synthesis, one of the two dyes still bound - indicative of a different type of cell wall. 2/ onlinelibrary.wiley.com/doi/10.1111/...

Pentapeptide‐rich peptidoglycan at the Bacillus subtilis cell‐division site

The large macromolecule peptidoglycan, that forms the bacterial cell wall, contains local differences in architecture and chemistry that encode the shape of the wall. We used different probes to labe...

onlinelibrary.wiley.com

Dirk-Jan Scheffers 🟥@dirkscheffers.bsky.social · 2mo ago

We would have never published a paper (see thread) if not for a control that delivered a surprise - that I didn’t believe at first and asked Danae to repeat multiple times before realizing she was on to something. 1/

Thiago Carvalho@cyrilpedia.bsky.social · 2mo ago

'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...

Max Heiman@heiman.bsky.social · 2mo ago

Fun read! Another classic example is Cynthia Kenyon's discovery that loss of the insulin receptor DAF-2 extends lifespan in C. elegans, which came out of the control for a clever mutant screen in which progeny of single F2s are sent into dauer with daf-2(ts) to track lifespan of the parent.

Thiago Carvalho@cyrilpedia.bsky.social · 2mo ago

'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...

Needhi Bhalla 💅🏽@needhibhalla.bsky.social · 2mo ago

“There are known knowns. These are things we know that we know. There are known unknowns. That is to say, there are things that we know we don't know. But there are also unknown unknowns. There are things we don't know we don't know.” The unknown unknowns are why I LOVE science 🧪

Thiago Carvalho@cyrilpedia.bsky.social · 2mo ago

'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...

Grant Jacobs BioinfoTools/NotJustDNA 🔬🧬🖥️✍️📚🇳🇿@notjustdna.bsky.social · 2mo ago

A nice reminder to think through _why_ controls failed

Thiago Carvalho@cyrilpedia.bsky.social · 2mo ago

'If a control experiment fails, does that mean that the entire experiment is poorly designed and you must restart from scratch? Often, yes— but not always. I present five examples where failed control experiments triggered entirely new fields of research.' link.springer.com/article/10.1...

The Fromm Lab@frommlab.bsky.social · 2mo ago

0/ 💡💡💡Had one of those slightly weird moments reading something today. Two seemingly very different research traditions—starting from opposite directions—appear to be converging on almost the same conclusion about one of biology’s biggest questions: How do genomes generate phenotypes? 👇🧵

André Schneider, University of Bern@schneian.bsky.social · 2mo ago

1000x linear expansion. Who would have thought this would be possible - From the inventor of the original expansion microscopy - This is absolutely fantastic! - Expansion microscopy is one of the most creative methods I have ever heard of in my 40 years of being a scientist - CONGRATS!

Ali Shaib@alishaib.bsky.social · 2mo ago

Hello #world, meet 1,000× Expansion Microscopy. A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy. Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us. Story: www.biorxiv.org/content/10.6...