Discover how laser capture microdissection is helping our researchers investigate cancer, autoimmune diseases, ageing and more. Check it out 👉https://sangerinstitute.blog/2026/09/22/what-is-laser-capture-microdissection/

What is laser capture microdissection? - Wellcome Sanger Institute Blog

We take an inside look into what laser capture microdissection is and how it is enabling scientists at the Wellcome Sanger Institute to precisely isolate cells and reveal detailed insights into biology and disease.

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Secure your in-person seat at #Epigenomics26 🧬🔬 🗓️ 4-6 November Join our open and friendly forum for global scientists sharing the latest insights on the genomics tools, technologies, and approaches driving studies into common human diseases. Register by 5 October ⏰ 👉 bit.ly/3ZTJI0a

📌 Don't miss our plenary #seminar tomorrow, with Dr. @mgarnett.bsky.social, from  @sangerinstitute.bsky.social.   🤝 Hosted by Dr. @batllelab.bsky.social  Register here ➡️ https://shorturl.at/erebY #CancerResearch

New species now out in @soilorganismsj.bsky.social! soil-organisms.org/SO/article/v... The latest addition to the UK's springtail fauna: Entomobrya terraeincognitae sp. nov. I found this species on fieldwork for my PhD @sangerinstitute.bsky.social at the Cambridge botanics. 🧵

James McCulloch@jamesimcc.bsky.social · 4w ago

The UK has a new species of springtail (to science)! I’m on my way to @nhm.org to drop off the type specimens. Name withheld so as not to violate the ICZN… but keep an eye out for the publication dropping shortly!

Eczema is a complex, chronic condition affecting millions worldwide. 🌏 For Eczema Awareness week, read our blog to explore what we know about eczema and what the future of research could look like. 👉 https://sangerinstitute.blog/2026/07/01/5-questions-on-eczema-with-anna-vathrakokoili-pournara/

5 questions on eczema with Anna Vathrakokoili Pournara - Wellcome Sanger Institute Blog

Red, itchy, unpredictable – eczema is more than just a skincare issue. It is a chronic inflammatory condition that affects people’s day-to-day lives. We explore what it is, what remains unclear and how researchers at the Wellcome Sanger Ins...

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Present your research on large-scale and AI-driven methods in genome biology at #GenomeInformatics26 🧬 Join us 2-4 December to connect with global field leaders and peers, and gain valuable feedback to support your future work. Submit an abstract by 5 October 👉 bit.ly/4bexmoH #Metagenomics

Senior bioinformatician and TED Fellow @marcelauliano.bsky.social is an expert in genomics and keeping science accessible. Read the blog to learn more ⤵️ sangerinstitute.blog/2026/09/15/s...

Sloths, sequencing and South America - Wellcome Sanger Institute Blog

From invasive mussels to sloths, Dr Marcela Uliano da Silva at the Wellcome Sanger Institute shares her varied career journey, with a consistent focus on inclusive research and effective scientific co...

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New research suggests that the risk of developing bacterial pneumonia, sepsis, and meningitis after air pollution exposure could depend on the subtype of bacteria a person has. Read the full story ⤵️

Bacteria in airway shape air pollution health risk

By studying over 59,000 cases of invasive disease caused by Streptococcus pneumoniae, experts have found that the subtype of bacteria influences the impact of environmental factors, such as air pollution, on disease risk.

sanger.ac.uk

Cancer treatments give a growth advantage to cells with particular genetic changes in healthy tissue. New research provides insights into chemotherapy side effects and drug resistance 💊 Read more ⤵️ https://www.sanger.ac.uk/news_item/chemotherapy-alters-darwinian-battleground-in-our-bodies/

Chemotherapy alters ‘Darwinian battleground’ in our bodies

Researchers uncover the genetic effects of cancer treatments in normal tissue, providing insights into side effects and drug resistance.

sanger.ac.uk

Researchers have found that some essential childhood chemotherapy drugs ‘age’ cells, possibly explaining why survivors can develop secondary cancers or liver disease later in life. 🧬

Vanessa Burns’s journey into genomics has taken some unexpected turns. Now a PhD student at the Sanger Institute, she is studying genetic variation and rare disease. 🧬 Read more on her story below 👇 https://sangerinstitute.blog/2026/09/08/dance-dna-and-trusting-lifes-detours/

Dance, DNA and trusting life’s detours - Wellcome Sanger Institute Blog

Navigating unexpected turns, discovering her passion and striving for work with real-world impact – reflections from Vanessa Burns, PhD student at the Wellcome Sanger Institute.

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Apply to do a PhD at @sangerinstitute.bsky.social with me on global genomics of Mycobacterium abscessus bbsrcdtp.lifesci.cam.ac.uk/project-refe... About the scheme: bbsrcdtp.lifesci.cam.ac.uk/application-...

We’re excited to launch Wellcome Sanger Institute Scientific Training and Events 🧬 After 30+ years of bringing researchers together through courses and conferences, this programme starts a new chapter with us - closer to Sanger's science, people and expertise. Find out more 👉 bit.ly/4gS40PL

What exactly is CRISPR-Cas – and where is genome editing heading next? ✂️ Sandeep Rajan shares how CRISPR works, how researchers are using it and why AI could transform our understanding of genetic variation. https://sangerinstitute.blog/2026/09/01/5-questions-on-crispr-cas-with-sandeep-rajan/

5 questions on CRISPR-Cas with Sandeep Rajan - Wellcome Sanger Institute Blog

From bacterial defence to breakthrough therapies, we explore how CRISPR-Cas is transforming research and healthcare, and how experts at the Wellcome Sanger Institute are refining the technology to make genome editing more scalable and effec...

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What makes us all different? A hidden source of genetic diversity has been uncovered in human sperm. Scientists found that a type of genetic recombination happens earlier than previously thought 🧬 https://www.sanger.ac.uk/news_item/hidden-source-of-genetic-diversity-found-in-human-sperm/

Hidden source of genetic diversity found in human sperm

New research provides a detailed view of how genetic diversity is generated in sperm and opens new opportunities to investigate the biological mechanisms underlying fertility, genome evolution, and inherited disease.

sanger.ac.uk

Why does the same genetic starting point lead to different outcomes for different people? A new project will use genomics to understand why some people with changes to the PTEN gene have an increased risk of cancer, and how this can inform future screening ⤵️ sangerinstitute.blog/2026/08/25/o...

Ambitious science can start in the most unglamorous places. In 2015, gastroenterologist Tim Raine and geneticist Carl Anderson had a casual conversation in an underground carpark, which led to the largest single-cell dataset of Inflammatory Bowel Disease (IBD)-relevant tissues

You swat them away, but more come to replace them – flies are survival experts. Read our latest blog to hear from our experts on why these two-winged wonders are worth studying. 🪰 https://sangerinstitute.blog/2026/08/20/six-facts-about-midges-and-gnats/

Six facts about midges and gnats - Wellcome Sanger Institute Blog

Small flies, big mysteries. Genomics can help reveal the evolutionary picture of these two-winged wonders. Small flies, big mysteries. Genomics can help reveal the evolutionary picture of these two-winged wonders.

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New insights could help clinicians identify children with a type of muscle cancer who may develop aggressive disease, even without the usual marker. 🧬 Read about the hidden genetic drivers of this cancer 👇 https://www.sanger.ac.uk/news_item/hidden-drivers-of-aggressive-childhood-cancer-revealed/

Ashleigh Williams, Advanced Research Assistant, shares how she found her way into sequencing, what a typical day looks like at Sanger and the unexpected turns along the way. Read her story 👉 https://sangerinstitute.blog/2026/08/11/world-class-science-one-sample-at-a-time/

World-class science, one sample at a time - Wellcome Sanger Institute Blog

From aspiring dentist to sequencing specialist, Ashleigh Williams, Advanced Research Assistant at the Wellcome Sanger Institute shares how following her curiosity led to a career full of cutting-edge technologies and unexpected turns.

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Scientists have uncovered new weak spots in cancer that could support the development of more effective therapies. 🧬 By using organoids created from patient cells, this work could help researchers develop better, less toxic treatments for patients⤵️ bit.ly/3Sh5t9M

Applications for the EMBL-EBI–Sanger Postdoc Programme are now open! Here, current fellows Leticia & Ouli talk about how working across the Institute and @ebi.embl.org enables interdisciplinary research tackling important questions in human health. Apply by 27 Sept: www.ebi.ac.uk/research/pos...

6 years 646 patients 1193 samples 100 endoscopists 9 lab scientists 3 postdocs 2 PhD students 502 courier runs from Addenbrooke’s Hospital to @sangerinstitute.bsky.social IBDverse is the largest single-cell dataset of Inflammatory Bowel Disease (IBD)—and generating the data for it was no mean feat

Professor Mark Blaxter shares the story behind a career shaped by curiosity – from childhood encyclopaedias and nematodes to leading Sanger’s Tree of Life programme. A fascinating read on science, collaboration and biodiversity. Read more 👉 https://bit.ly/4pFJoOs

“I stand on the shoulders of giants”: Mark Blaxter on being a bookworm, building a programme from scratch and his love of small wiggly creatures - Wellcome Sanger Institute Blog

Professor Mark Blaxter, Head of the Tree of Life programme at the Wellcome Sanger Institute, traces a path from books to nematodes, community gardens to new technologies – guided by a lifelong interest in the world around him.

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The #BigButterflyCount is back! 🦋 Sanger scientist Charlotte Wright studies these insects by peering into their evolutionary history ⤵️ https://sangerinstitute.blog/2025/12/11/five-questions-on-butterfly-and-moth-genomics-with-charlotte-wright/

Five questions on butterfly and moth genomics with Charlotte Wright - Wellcome Sanger Institute Blog

Drawn to genomics like a moth to a flame, Wellcome Sanger Institute Postdoctoral Fellow, Dr Charlotte Wright, shares with us how she uses genomics to shed light on the evolutionary history of butterflies and moths, and how they might change...

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Bad hair day? Blame biology. 💇 Six surprising hair facts you did not ask for – but will definitely share. Plus, how our researchers are uncovering the science behind every strand. Read more 👉 sangerinstitute.blog/2026/07/21/s....

Six things you may not know about hair - Wellcome Sanger Institute Blog

There may be a series of products for it and even a musical named after it – but what do we actually know about hair? And how are researchers at the Wellcome Sanger Institute working to uncover what i...

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Early warning signs of drug resistance in parasitic worms have been revealed 📢 Scientists have identified genetic changes in the parasite that causes schistosomiasis that may reduce its response to praziquantel, the only widely available treatment. Read more here 👇 bit.ly/4yuCEXP

Parasitic worms are a big deal, but their genomes have been tricky to study 🪱. New technologies now let us generate high-quality genomes from individual worms, opening the door to a new era of parasite genomics. Steve Doyle (@stephenrdoyle.bsky.social) and I discuss what this means for the field 👇

Trends in Parasitology@cp-trendsparasitol.bsky.social · 3mo ago

Sequencing parasite genomes, one worm at a time

❄️🧬 Can we generate high-quality reference genomes without the cold chain? A new study suggests the answer is yes. DNA preserved at room temperature for up to one week produced chromosome-scale reference genomes. 📖 tinyurl.com/3zwtj9ka #Genomes @gigascience.bsky.social @sangerinstitute.bsky.social

Cholera is an ancient disease that still impacts millions of people today. Here, Lia Bote answers our questions about the past, present, and future of cholera research. ⤵️ https://sangerinstitute.blog/2026/07/14/5-questions-on-cholera-with-lia-bote/

5 questions on Cholera with Lia Bote - Wellcome Sanger Institute Blog

We are in the seventh global cholera pandemic, which has been going on since the early 1960s. But what is cholera, and why is it still a global issue? Lia Bote, PhD student at the Wellcome Sanger Institute, answers our questions about the p...

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