In #GENETICS, @jsrinivasanwpi.bsky.social and the team present a rescue-by-feeding approach, showing that feeding engineered E. coli containing neuropeptides to #Celegans mutants can successfully rescue behavior defects in worms. buff.ly/Qdw9Nsq
Prof. Jagan Srinivasan
@jsrinivasanwpi.bsky.social
An immigrant neuroscientist who endeavors to understand the brain. Systems Neuroscience Laboratory, Worcester Polytechnic Institute in Massachusetts, USA. A son, husband, father, and an immigrant !
A new story out of our lab from the talented grad student Elizabeth Diloreto in collaboration with the Javier Irazoqui lab at UMASSCHAN. www.biorxiv.org/content/10.1...
Staphylococcus aureus-Induced Degeneration of Nociceptive Neurons in Caenorhabditis elegans
Background In all animals, the nervous system senses microbial signals to influence host defense. Despite emerging as important sensors of infection to regulate immunity and inflammation, the mechanis...
biorxiv.org
Two papers in two weeksAnother paper from our lab is out for review! This paper unravels how serotonin signaling via specific neurons is involved in deciphering conflicting olfactory stimuli. Great work from my grad student Caroline Muirhead, the lead author. www.biorxiv.org/content/10.1...
Serotonergic signaling governs C. elegans sensory response to conflicting olfactory stimuli
Neural circuits that consolidate sensory cues are essential for neurological functioning. Neural circuits that perform sensory integration can vary greatly because the sensory processing regions of th...
biorxiv.org
Holy microscopes Batman. This is shockingly good and unexpected news. Let me know if you'd like an update to your @the.3i.social microscope or a replacement to some obsolete microscopy equipment in your lab. 3i makes modular tools that can fit quite cleanly into the supplement program. #specificaims
a man in a robin costume is holding a sword and says holy smoke
ALT: a man in a robin costume is holding a sword and says holy smoke
media.tenor.com
Tim Stearns@stearnslab.bsky.social · last yr.NIGMS administrative supplements are back! These are given at the discretion of program officers and are not reviewed by study sections. Renewing obsolete equipment is a priority. loop.nigms.nih.gov/2025/03/nigm...
Exciting new work from our lab in collaboration with the @rnareylab.bsky.social labs. www.biorxiv.org/content/10.1...
Harnessing Microbial Tools: Escherichia coli as a Vehicle for Neuropeptide Functional Analysis in Caenorhabditis elegans
Animals respond to changes in their environment and internal states via neuromodulation. Neuropeptides modulate neural circuits with flexibility because one gene can produce either multiple copies of ...
biorxiv.org
Hello Blue sky universe! Navigating this social space for colleagues and friends!