I'm happy to share that I’ll be presenting our work on exploiting tissue regeneration for durable mucosal healing at the 12th Takeda Science Foundation Symposium on PharmaSciences – ORGANOID 4D: Development, Disease, Diversity and Discovery, taking place in Osaka, Japan on 23–24 January 2026 🇯🇵
Srustidhar Das
@srudas.bsky.social
Stem cell biologist | Organoid aficionado | History enthusiast | Exploring tissue homeostasis at the intersection of regeneration & cancer
🎧 Excited to share my Henry Stewart Talks (#HSTalks) interview on our recent @natureportfolio.nature.com paper — showing how liver X receptor (LXR) acts as a molecular “rheostat,” boosting intestinal repair while restraining tumor growth. 👉 Take a listen here: doi.org/10.69645/QUT...
How liver X receptor regulates intestinal regeneration and tumor growth
Click to launch & play an online audio visual presentation by Dr. Srustidhar Das on How liver X receptor regulates intestinal regeneration and tumor growth, part of a collection of multimedia lectures...
doi.org
Finally thrilled to share this - my first real attempt at #SciComm! 🎉 Grateful to the amazing @investnscience.bsky.social team for organizing a fantastic workshop, providing the platform, editing support, and most importantly, encouraging critical thinking to simplify the message. Thank you!!!
Could there be a better treatment for IBD? @srudas.bsky.social studies treatments for Inflammatory Bowel Disease using therapies to regrow gut lining - addressing the root cause of the disease and using the body to heal itself. #academicsky #researchsky #IBD #IBDtreatments #investnscience
Fascinating new @natureportfolio.bsky.social study from @thevinodlab.bsky.social @mskcancercenter.bsky.social:IL33, an alarmin from inflamed tissues, drives ILC2 migration from the gut to the pancreas, forming TLS with anti-tumor effects in PDAC. www.nature.com/articles/s41...
IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer - Nature
IL-33 induces tertiary lymphoid structures.
nature.com
We just can't stop recruiting! Associate professor in cell and molecular biology @dunnschool, with a preference for immunology, inflammation and/or infection - all defined broadly Come and be our colleague Deadline 28 Feb, please spread the word www.path.ox.ac.uk/vacancy/asso...
Big thanks to Amy E. Baek for spotlighting our recently published work in Nature @nature.com in the Editor's Choice section of @ScienceSignaling @science.org! www.science.org/doi/10.1126/...
Healing limited
Activation of liver X receptor promotes tissue regeneration over neoplastic transformation.
science.org
Thanks Cancer Discovery Journal, @AACR for highlighting our recently published work @natureportfolio.bsky.social!!! The Liver X Receptor Axis Balances Intestinal Regeneration and Tumorigenesis doi.org/10.1158/2159....
The Liver X Receptor Axis Balances Intestinal Regeneration and Tumorigenesis
Major Finding: The liver X receptor (LXR) pathway drives intestinal regeneration and limits tumorigenesis.Concept: Transcriptomic and pharmacologic studies define a CYP27A1–LXR–TLS signaling axis in i...
doi.org
An epithelial adaptation mechanism to damage, whereby LXR functions as a rheostat, promoting tissue repair while limiting tumorigenesis @ejvillablanca.bsky.social @srudas.bsky.social nature.com/articles/s41...
Do you wonder if #regeneration and #tumorigenesis are always linked, or can they be unlinked to maintain tissue homeostasis? 🤔 Excited to share our latest work published in @Nature, where we explore this fundamental question in the #gut! Link: www.nature.com/articles/s41... 🧵👇