#ASHG2025 is underway and it's broken the record for the world's largest #genetics conference! As a member of the program committee (@sgrayg.bsky.social), we'd like to thank everyone at @geneticssociety.bsky.social for making this possible. We can't wait to see what the next few days hold... 🧬🤝

Yale has established a new PhD program in Human Genome Sciences and will be accepting applications this fall. We are also searching for an Associate Director of Student Services (a PhD-level position). Learn more here: medicine.yale.edu/bbs/tracks/h... careers.yale.edu/us/en/job/YU...

Human Genome Sciences

The overall goal of the Human Genome Sciences (HGS) track is to train the next generation of scientists in the areas of human genomics, genetics, and

medicine.yale.edu

After spending tons of time rebutting our trainee's grant termination.. this response doesn't suggest a 'careful assessment' There aren't mechanisms that support mid-PhD trainees, so theres nothing to apply to, even though it scored in the top % of all apps. Not to mention the demotivation. Ugh.

🧠 MPRA + AI to decipher rules of enhancer grammar. I wrote some thoughts about the fantastic and inspiring work by Robert Frömel & colleagues from @larsplus.bsky.social lab at @crg.eu @upf.edu 👏👏👏 sciencemediacentre.es/en/design-dn...

As a follow-up to the Kaiser interview, here is my exchange with Dr. Bhattacharya starting Sunday evening... 1/n

Proud to share our lab’s first student preprint!🚀@j-c-butts.bsky.social, @alwaysrong.bsky.social, @sagergosai.bsky.social leveraged our MPRA models to predict variant effects, providing scores for the complete catalog of human variation. Grateful for another fun collab with @stevereilly.bsky.social.

John Butts@j-c-butts.bsky.social · last yr.

Excited to share our MPAC preprint, a scalable ensemble of ML models for genome-wide non-coding variant effect prediction and our findings from 575M predictions across databases including @ukbiobank.bsky.social, GTEx, ClinVar, COSMIC, and @gnomad-project.bsky.social www.biorxiv.org/content/10.1...

Incredibly frustrated today that we had a PhD trainee's NIH grant TERMINATED. He EARNED it by scoring in the top %. Would love to hear from #murkowski @sendansullivan.bsky.social @nickbegich.bsky.social think about a bright AK native son's prospects getting cut short due to DOGE lunacy.

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media.tenor.com

Thanks #MITS2025 for inviting me to speak about our deep learning-based search for variants under positive selection in the human genome; more to come! @pardissabeti.bsky.social @stevereilly.bsky.social

Craig Anderson@craigandersn.bsky.social · last yr.

Arya Rao in the search for adaptive traits #MITS25

ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n

the word alert is in a purple circle

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media.tenor.com

Read through to see our new collaborative work predicting the effects of regulatory variation, for complex traits, rare disease, cancer, and evolution by making ML models of MPRA and scaling to the entire genome.

John Butts@j-c-butts.bsky.social · last yr.

Excited to share our MPAC preprint, a scalable ensemble of ML models for genome-wide non-coding variant effect prediction and our findings from 575M predictions across databases including @ukbiobank.bsky.social, GTEx, ClinVar, COSMIC, and @gnomad-project.bsky.social www.biorxiv.org/content/10.1...

Hello Bluesky. The Reilly lab fully made the jump from twitter. Thought it was time to say hello, so: hello! Excited to join a great community of scientists here!