Tamara Tilburgs
@ttilburgs.bsky.social
The Tilburgs lab at Cincinnati Children’s investigates the fascinating mechanisms of maternal-fetal tolerance and placental immunity in humans. All views are my own.
Do you need primary HLA-G/C+ EVT or primary EVT-like cell lines from preterm, preeclampsia or healthy term pregnancies for immune cell - EVT cultures and mechanistic studies? Check out our new video protocol just published in JoVE. Made possible by Angel, Shweta, & Sayaka❤️. hubs.ly/Q04ptKq50
If you love High Dimensional Flow Cytometry, check out our new paper and R based tool: CytoBatchFlagR, to help QC your data and improve your downstream clustering and detailed analysis! doi.org/10.1002/cyto...
Purification of HLA-G+ Extravillous Trophoblasts from Human Term Placental Tissues for Phenotyping and Functional Analysis @ttilburgs.bsky.social @cincyresearch.bsky.social app.jove.com/t/69545/puri...
Thank you to the Editors and Trends in Immunology for putting together this wonderful special issue on maternal–fetal & early-life immunity! ❤️
Trends in Immunology@cp-trendsimmuno.bsky.social · 7mo agoThe profound connection between mother & child reflects a dynamic immunological transformation that extends beyond gestation and early life. Explore how maternal–fetal immunity & early-life exposures shape long-term health outcomes in our new special issue. www.cell.com/immunology/c...
Review @cp-trendsimmuno.bsky.social @ttilburgs.bsky.social @cincyresearch.bsky.social Decidual immune activation by extravillous trophoblasts drives maternal-fetal tolerance and immunity www.sciencedirect.com/science/arti...
Great start of the week! Here I discuss my favorite topic on how the activation of decidual natural killer and T cells, through recognition of key extravillous trophoblast ligands, promotes placentation, tolerance, and immunity. Let me know what YOU think! authors.elsevier.com/sd/article/S...
Its published!!! Congratulations Zach, Shruti & Team!🥂 A story about how maternal decidual CD4 T cells are not all Treg, and that these effector memory and tissue resident memory cells recognize and respond to foreign fetal allo-antigens. doi-org.uc.idm.oclc.org/10.1111/aji....
Check out this new podcast! and the many other ones before this one on "making sense of pregnancy" podcasts.apple.com/us/podcast/w...
When's the best time to intervene in the health of a pregnancy? Before it starts: Conversation with Dr. Tamara Tilburgs, Part I
Podcast Episode · Making Sense of Pregnancy: What Experts Want you To Know About Your Body · 11/19/2025 · 29m
podcasts.apple.com
🚨 We're hiring a Postdoc to investigate the fascinating mechanisms of maternal-fetal tolerance & immunity! If you're passionate about immunology, and ready to make discoveries, apply here: //https://lnkd.in/g2HyCd-W #PostdocOpportunity #Immunology #Hiring #AcademicJobs #MaternalFetalImmunology
Delighted to change Assistant to Associate today!! Can't believe how lucky I am to work at an amazing place, with incredible mentors, super talented trainees, & tons of friends and collaborators on my favorite placenta projects!! I may need to take an extra long Labor Day weekend to celebrate 🥂
I am honored to be on this week's Immunology Podcast to discuss placental tolerance & immunity in pregnancy!
Immunology Podcast@immunologypodcast.com · last yr.Check out our latest episode! Dr. Tamara Tilburgs (@ttilburgs.bsky.social) from @cincychildrens.bsky.social talks about the mechanisms of immune tolerance during pregnancy! Listen now: bit.ly/3H7ZM8H
Delighted with our new publication showing how natural microbial exposure of pregnant mice enhances T cell diversity and residency at the maternal-fetal interface and resembles human decidual immune populations with increased fidelity. www.frontiersin.org/journals/imm...
Delighted with my labs new publication on how decidual NK cells utilize the anti-microbial peptide granulysin for immune defense of placental tissues! ❤️
Granulysin-high decidual NK cells in macaques and humans share signatures of immune defense: Cell Reports www.cell.com/cell-reports...
Granulysin-high decidual NK cells in macaques and humans share signatures of immune defense
Prasanphanich et al. demonstrate that granulysin-high decidual natural killer cells (dNKs) of rhesus macaques and humans share conserved signatures of antimicrobial defense and immunoregulation. Moreo...
cell.com
Congratulations Nathan and Team!! Very cool paper!!
Nathan Salomonis@nathansalomonis.bsky.social · last yr.New in STM, check out our integrative bulk & single-cell long-read analysis to discover and test new therapies in leukemia. We developed OncoSplice, to define new splicing defined subtypes and predict regulators. PRMT5 inhibition partially rescued mis-splicing & inhibited leukemic growth. More soon!
Can't wait to read this one! Congratulations Krish & Team!!
Waggoner Lab@labwaggoner.bsky.social · 2y agoB cell repertoire of children with atopic dermatitis exhibit altered IgE maturation associated with allergic food sensitization www.biorxiv.org/content/10.1... @cincyresearch.bsky.social @krishnaroskin.bsky.social
To keep me sane & centered, I made and fussed over this big clay pot last night! This morning, I feel refreshed and ready to focus on science! I think I may need more of this for a while...
Thank you Dave and Sebastiaan, for writing this nice piece about Frans! “Carpe Diem" and "Daar zit wel muziek in" will be my favorite words remembering Frans! doi.org/10.3389/ti.2...
Frontiers Publishing Partnerships | In Memoriam Frans H. J. Claas
was the first to show that an increased level of HLA triplet mismatches was associated with an increased chance of de novo donor-specific antibody (dnDSA) fo...
doi.org
@labwaggoner.bsky.social @cincyresearch.bsky.social are the first to describe how liver protein prothrombin prevents fatal immunopathology during chronic virus infection in mice. buff.ly/A6szRmm
Thanks for sharing this data, Jeremy! Looks absolutely terrifying to me...
Jeremy Berg@jeremymberg.bsky.social · 2y agoExtending my grant update this morning. Here are data limited to new and competitive renewal applications. The Pause is dead, Long live the Pause...
The positive economic benefit of Cincinnati Children's on Ohio is at risk cincinnatichildrenshospitalmc.us.newsweaver.com/1m1vhmv4sc/m...
Can anyone please sue them for this and open the federal register? Our R01 scored a 10th percentile and should have gone through council in January... It is insanely stressful to run a lab these days...
Jeremy Berg@jeremymberg.bsky.social · 2y agoGuardian story about Federal Register issue is up. www.theguardian.com/us-news/2025...
