Happy to share our new paper in Cell Reports! We show that ACSF3 links feeding rhythms to hepatic metabolism through rhythmic lysine malonylation, regulating glucose/lipid metabolism and autophagy. www.sciencedirect.com/science/arti...
Diurnal regulation of Acyl-CoA synthetase 3 (ACSF3) governs rhythmic mitochondrial lysine-malonylation and daily hepatic metabolism
Hepatic daily rhythms are coordinated by feeding and the molecular circadian clock, ensuring metabolic homeostasis. Disrupted feeding schedules promot…
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