@kirstin-rollins.bsky.social, @mmorrissey.bsky.social et al show that #macrophages attack adherent cells using #trogocytosis instead of #phagocytosis. Reducing adhesion increased phagocytosis. Mitotic cells, which disassemble adhesions, are more vulnerable to phagocytosis rupress.org/jcb/article/...
@kirstin-rollins.bsky.social
Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis https://www.biorxiv.org/content/10.1101/2025.02.06.636906v1