Very happy to see the June cover of natBME featuring our paper on branched #organoids to capture pancreatic cancer heterogeneity! Thanks to @maxreichertmd.bsky.social @tum.de and our amazing team!! Thanks to @ella-maru.bsky.social for the cover design! www.nature.com/articles/s41...

🚨 Our new #preprint is out! doi.org/10.1101/2025... We used #PerturbMap spatial functional genomics in pancreatic cancer to track tumor clone dynamics and uncover how extracellular factors like Serpine1 and Serpinb2 drive immune evasion. 🧵 (1/8)

Want to 👀 real phenotypic differences in #PDAC epithelial and mesenchymal #organoids ? @maxreichertmd.bsky.social Check these cool videos we made for our new paper 🤩✌️ @natureportfolio.bsky.social 👉 www.nature.com/articles/s41... 👉 rdcu.be/d3qyD

I am so excited to share the biggest (and best) part of my #PhD in @maxreichertmd.bsky.social lab We show how inter/intra-tumoral #heterogeneity impacts plasticity and treatment resistance by using #PDAC #organoids @natureportfolio.bsky.social www.nature.com/articles/s41...

Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma - Nature Biomedical Engineering

Branched organoids embedded in collagen gels can recapitulate the phenotypic landscape and pronounced molecular and morphological heterogeneity of pancreatic ductal adenocarcinoma.

nature.com

I think it’s about time to add another one (better this time 🤣) on my collection!! Stay tuned for nexts weeks announcement from the final chapter of my #PhD work at Max Reichert’s lab and the TU Munich!! #organoids #morphogenesis #plasticity #treatmentresistance #pancreatic #cancer