Soroush Mirjalili

@soroushmirjalili.bsky.social

Postdoc in the Kuhl Lab at the University of Oregon, PhD from UT Austin. Episodic Memory | Cognitive Neuroscience | Computational Neuroscience | Cognitive Aging. 🌿 -> 🐝 -> 🐂 -> 🦆, he/him soroushmirjalili.com

Imagine two people standing in the same spot, looking at the same Goya. They inspect exactly the same parts of the painting, but in a different order. Later, they talk about what they saw. Ignoring all other differences: are the memories they formed identical?

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Hi all, I'm happy to announce that I have started at the University of Oregon as an assistant professor! My group will use computational methods to study learning and synaptic plasticity. I will be hiring grad students this year--please reach out if you're interested! colinbre@uoregon.edu

Excited to see this work published! We find that the brain codes semantic relationships similar to contextual LLMs (like GPT2) but unlike LLMs, uses contrastive coding to prevent confusion of highly similar words. Many thanks to the reviewers and BCM neurosurgery team! www.nature.com/articles/s41...

A population code for semantics in human hippocampus - Nature Neuroscience

Franch et al. show that human hippocampal neurons encode the meanings of the words we hear through distributed, context-sensitive population activity that mirrors some features of large language model...

nature.com

How do we prevent memories from competing to guide attention? More distinct hippocampal representations for competing memories are linked to precise preparatory coding in visual cortex & more accurate eye movements to target locations. Thrilled to share this work by the incomparable Serra Favila!

Hippocampal mechanisms underlying the resolution of competition in memory and perception - Nature Communications

Memory and perception both require selecting behaviorally relevant information. Here, the authors show that more distinct hippocampal memories are linked to precise anticipatory signals in visual cort...

nature.com

If an action results in error, each neuron requires an individualized teaching signal that guides change in its output. This is the credit assignment problem of learning. Are there neurons in the brain that can compute such a sophisticated teaching signal? Yes. www.biorxiv.org/content/10.6...

Climbing fibers encode the gradient of a loss function for the cerebellum

Neurons in the brain are often many synapses away from motoneurons, yet if a movement results in error, each distant neuron needs a teacher that considers its specific contribution to production of th...

biorxiv.org

Excited to share that my first-ever first-author paper (w/ @atabk.bsky.social @AngeliqueDelarazan @zreagh.bsky.social) is now out in PNAS! Building a story to link two objects boosts associative memory and inference, but not memory for the objects themselves. www.pnas.org/doi/10.1073/... 🧵

Active linking through narratives facilitates associative inference | PNAS

In daily life, we often draw inferences about novel associations from prior experiences. This ability, associative inference, is thought to be a ke...

pnas.org

Very excited to share our new review on C-HORSE, our model of the hippocampus! We think there is very encouraging alignment between C-HORSE proposals and the extant empirical literature, though we also note plenty of areas for further model development. royalsocietypublishing.org/rstb/article...

Evidence for complementary learning systems within the hippocampus

Abstract. Decades of research have established the hippocampus as central to episodic memory, but growing evidence suggests that it also contributes to str

royalsocietypublishing.org

New preprint! We show low arousal states promote hippocampal ripple genesis in sleep and wake. This bridges rodent work, where ripples predominate during sleep, with human studies reporting ripples during active behavior, identifying low arousal as a common mechanism www.biorxiv.org/content/10.6...

Arousal state modulates human hippocampal ripples

Hippocampal ripples are transient, high-frequency oscillations linked to memory replay and consolidation. Ripples are well-characterized in rodents to occur during periods of behavioral inactivity (i....

biorxiv.org