🧵 New preprint out! We asked: what happens to gut bacteria when the intestine is under chronic inflammation (IBD)? Turns out, the host's inflammatory state reshapes how they evolve, and the results are pretty striking. A thread 👇
biorxiv.org
Hugo C. Barreto
@hugocbarreto.bsky.social
Marie Skłodowska-Curie Postdoc Fellow Institut Cochin Tenaillon-Matic Lab. PhD alumni Instituto Gulbenkian de Ciência. Interested in host-microbe interactions and evolution.
🧵 New preprint out! We asked: what happens to gut bacteria when the intestine is under chronic inflammation (IBD)? Turns out, the host's inflammatory state reshapes how they evolve, and the results are pretty striking. A thread 👇
biorxiv.org
Great way to finish the year! Here showing that the amazing gut Microbiota Isolate - ARO112 can accelerate microbiota recovery after perturbations and protect against gut Inflammation. This work was possible given the hard and brilliant work of @vhrcabral.bsky.social and @aritaoliveira.bsky.social
Thrilled to share that our new paper is out now in @natcomms.nature.com 🎉 Huge congrats to @vhrcabral.bsky.social and @karinaxavierlab.bsky.social on this major work. We found that our Klebsiella ARO112 can break the antibiotic/inflammation cycle in an IBD model
We are so pleased to welcome Emma Agnew from @pasteur.fr at @institutcochin.bsky.social for her seminar on the Candida Corkscrew: a morphological strategy of epithelial invasion. Another great talk from the @parispostdocs.bsky.social seminar series! @albiglero.bsky.social @hugocbarreto.bsky.social
#microsky journals.plos.org/plosgenetics...
Clonal interference and genomic repair during strain coexistence in the gut
Author summary Escherichia coli is a common species colonizing the intestine of many mammals including humans. Typically, more than one strain of this species colonizes the gut at a given time. While ...
journals.plos.org
What a great talk Barbara Da Fonseca from @pasteur.fr gave at @institutcochin.bsky.social today! She talked about her project on "Lung organoid-on-chip models to study respiratory infections". The talk was follow by a lively discussion. Another great talk of the @parispostdocs.bsky.social #PostDoc
Paris Post-doc Seminar: Barbara de Faria Da Fonseca (Biomaterials & Microfluidics core facility @pasteur.fr) will give a seminar @institutcochin.bsky.social on April 10 at noon: Lung #organoid-on-chip models to study respiratory infections institutcochin.fr/en/agenda/lu... @parispostdocs.bsky.social
Lung organoid-on-chip models to study respiratory infections
The development of complex in vitro models, such as organoids, gastruloids and organ-on-chips systems, will allow the better understanding of human biological processes that are otherwise difficult to...
institutcochin.fr
Last week, we had the pleasure to welcome Marion Guerin from @pasteur.fr for a @parispostdocs.bsky.social seminar at @institutcochin.bsky.social. A great presentation, lots of questions and a lively discussion. That's what we like to see! #postdoc @albiglero.bsky.social @hugocbarreto.bsky.social
Save the date 📅: The PhD Summer School on Host-microbe Symbioses is taking place from 6-19 of July in Oeiras, Portugal. Registration is opening soon! Learn more 👉 gimm.idloom.events/phd-summer-s... @gimmfoundation.bsky.social @moorefound.bsky.social @crc1182.bsky.social #CIFAR #CBR
We are looking for a #Postdoc to join our team to work on a funded project by La Ligue investigating the role of #gut permeability as a cause of #cancer with #age. 🐟🐟🐟 #zebrafish #telomerase #microbiome DEADLINE: 29/Jan/2025 Please help us spread the word! 🙏
Happy to welcome François-Xavier Mauvais at @institutcochin.bsky.social for a Paris Postdocs seminar. It was an enlightening talk. Protocols are being exchanged and collaborations are emerging. This is what these seminars are all about. @hugocbarreto.bsky.social @albiglero.bsky.social
Publication online in Nucleic Acids research by Ivan Matic's team: Genome-wide mapping of spontaneous DNA replication error-hotspots using mismatch repair proteins in rapidly proliferating Escherichia coli institutcochin.fr/en/actualite... @cnrsbiologie.bsky.social
Genome-wide map of DNA replication error hotspots in the Escherichia coli genome
This study conducted by Ivan Matic’s team presents a comprehensive genome-wide map of DNA replication error hotspots in the Escherichia coli genome, shedding light on the mechanisms that undermine the...
institutcochin.fr