Polina Novikova

@pnovik.bsky.social

Biologist, adventurer novikovalab.org novikovalab.be arabidopsislyrata.org

New preprint with grad student @linhngk.bsky.social. Big mystery in plants is why do their telomere length vary? We answered by analyzing 10Tb or 1.4 billion reads from 257 species of algae to land plants. We propose ecological adaptation shapes telomere length in plants. shorturl.at/0ox4x

Biogeographic cline is associated with the global plant telomere length variation

Telomeres have the crucial role of protecting chromosome ends and its length varies significantly between organisms. What evolutionary factor shapes this natural variation has been a long standing que...

biorxiv.org

Delighted to share our paper on neo-chromosomes! We induced centromere fission using CRISPR in Arabidopsis and increased the chromosome count from n=5 to n=6. The broken chromosomes ends quickly “healed” by adding telomeres de novo and the new karyotype is stable through mitosis and meiosis! 1/3

Ian Henderson@hendersi.bsky.social · 2mo ago

CRISPR-mediated centromere fission generates neochromosomes with distorted meiotic inheritance in Arabidopsis biorxiv.org/content/10.6... new preprint from us - includes changing the Arabidopsis karyotype from 5 -> 6 chromosomes using Cas9 & outcomes of 5/6 chromosome hybrid meiosis