Robin Burns

@robinburns.bsky.social

Broodbank Fellow. PDRA Caius College. Evolution of hybrids, polyploids and centromeres

We (@rileyshultz.bsky.social) tracked a recessive mutation from birth to death in honey bees. It causes ivory eyes. We collaborated across the continent to identify the mutation and it's downstream effects. Ultimately it is purified through selection on drones. We think Hamilton would be pleased!

Molecular Biology and Evolution@molbioevol.bsky.social · 6d ago

Shultz @beeharpur.bsky.social et al. documented the trajectory of a spontaneous deleterious mutation from its origin in a single queen to its extinction, directly observing how haplodiploidy exposes recessive alleles to immediate purifying selection 🔗 doi.org/10.1093/molbev/msag156 #societyjournal

MBE | The life history of recessive deleterious alleles as seen through the eyes of a honey bee (Apis mellifera)
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The centromere performs an essential function during cell division, yet its DNA sequence can evolve remarkably rapidly—a puzzle known as the centromere paradox. How can function remain conserved when sequence does not? 🧵 1/4

Avocados come in 2 varieties - A-types start each day female and switch to male midday. B-types do the reverse. In work just published from the last chapter of my PhD, we show this system evolved 40+million yrs ago and is regulated by alleles of 1 transcription factor www.pnas.org/doi/10.1073/...

Balanced polymorphism in a floral transcription factor underlies the ancient rhythm of daily sex alternation in avocado | PNAS

In avocado and certain wild relatives in Lauraceae, a highly synchronized daily rhythm of floral sex timing promotes cross-pollination between two ...

pnas.org

Delighted to share our paper on neo-chromosomes! We induced centromere fission using CRISPR in Arabidopsis and increased the chromosome count from n=5 to n=6. The broken chromosomes ends quickly “healed” by adding telomeres de novo and the new karyotype is stable through mitosis and meiosis! 1/3

Ian Henderson@hendersi.bsky.social · 2w ago

CRISPR-mediated centromere fission generates neochromosomes with distorted meiotic inheritance in Arabidopsis biorxiv.org/content/10.6... new preprint from us - includes changing the Arabidopsis karyotype from 5 -> 6 chromosomes using Cas9 & outcomes of 5/6 chromosome hybrid meiosis

Excited to share the SNPstar! preprint! 🌿 SNPstar helps researchers explore how natural variation in Arabidopsis thaliana affects protein structure and function by integrating SNP data, AlphaFold3 models, stability predictions, population context, and more. www.biorxiv.org/content/10.6...

SNPstar: A Web Server Linking Allelic Variation to Protein Structure and Function in Arabidopsis thaliana

Understanding how natural genetic variants affect protein structure and function is central to plant biology. The 1001 Genomes Project has catalogued millions of single nucleotide polymorphisms (SNPs)...

biorxiv.org

How do transposons jump when they’re released from host control? I babysat two chromosomes for 2 years, making sure they are ok without most piRNAs. Here’s what we found & excited to share my 1st postdoc paper: “piRNA loss unleashes episodic transposition bursts” www.biorxiv.org/content/10.6...

piRNA loss unleashes episodic transposition bursts

In Metazoa, transposon expression is suppressed by the piRNA pathway, and disruption of this pathway leads to rampant transposon expression. However, it remains unclear whether increased transposon ex...

biorxiv.org

The Flame Robin Males perch in high, open spots to sing, showing off their vibrant orange chest. Despite its subtlety, the song effectively communicates with rivals and potential partners. 12-14cm found: Australia and Tasmania

A whale graveyard millions of years old and over a thousand kilometers long has been discovered. Not only could it tell us more about the evolution of a mysterious deep-sea denizen, but it’s a prime site for discovering brand new species, too.

Guten Morgen Bluesky 🌤 ☕️ 🍀 🕊 Hier ein paar Überlebende, die sich mit mir über die gestrige Rettungsaktion freuen. Das ist doch kein 'Unkraut' sondern das sind wunderschöne Wildblumen an denen sich hier jeder erfreut. Habt einen zauberhaften Tag.

Direkt am Bach stehen 3 verschiedene Arten der Akelei, blau, rose' und rot.

We have a new paper out on one of evolution’s “classic” systems: Galápagos Scalesia plants! 🌿 How do you generate huge differences in leaf shape across species in <1 million years? We combined genomics + morphology + transcriptomics across the full radiation 👇

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