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Oscar Kelly

@oscarkelly.bsky.social

PhD Student in Inorganic Chemistry @ Trinity College Dublin

1 Posts56 Follower128 Folgt
Anthony Moser@anthonymoser.com · 3w ago

as a hater let me acknowledge something ai is good at: producing irritating discourse at scale this is usually because, like "ai" itself, people are talking about different things like they are one thing so let me disentangle, with statements numbered for easy disagreement

Benjamin Tausig@burrata.bsky.social · 4w ago

Hi! I'm a university president, seeking advice about AI. On one hand, AI actively guts education and might kill everyone. But on the other hand, taking money from AI companies means becoming dependent on an industry that could crash at any moment. So should we go all in?

Eoghan Sweeney@eoghan.eurosky.social · 2mo ago

Superb piece on the death of Dublin, killed by greed. It's not immigrants who wielded the blade; it's our own, developers and property owners obsessed with squeezing every penny of profit out of the city, on the backs of stressed, overworked people they've priced out of living in it #spéirġorm

Dublin is now a shell of its once former self - opinion - Western People

Dublin is now a shell of its once former self - opinion - Western People

westernpeople.ie

Andrew Robinson (no, not Garak)@andrewr.bsky.social · 10mo ago

See also teaching. It's important that the student does the work. Outsourcing to an LLM does nothing for learning necessary skills. And universities having policies to "Ensure students are trained on AI" is complete nonsense. Any graduate can easily use AI.

Faine Greenwood@faineg.com · 10mo ago

suspect a big reason why many academics and others who work in areas where getting facts RIGHT is key are disinterested in using LLMs for research: they’ve tried it, they keep noticing major errors in output, and they conclude that having to verify all that doesn’t actually save them time.

Philip Ball@philipcball.bsky.social · 11mo ago

It seems this can't be emphasized enough. Chatbots and LLMs do not make mistakes (excepting any bugs in the code). They do not lie. They do not blackmail or cheat. They follow statistics. When the people who build these systems don't tell you this, they are either deluded or trying to mislead.

Katie Mack@astrokatie.com · last yr.

When a chatbot gets something wrong, it’s not because it made an error. It’s because on that roll of the dice, it happened to string together a group of words that, when read by a human, represents something false. But it was working entirely as designed. It was supposed to make a sentence & it did.

Oscar Kelly@oscarkelly.bsky.social · last yr.

Delighted to finally share this work in @jacs.acspublications.org . Big thanks to @fenicu.bsky.social , @marcelswart.bsky.social and Brendan Twamley. Check it out! 👇🏻🧪 #chemsky

Bioinspired Inorganic Chemistry, Dublin@fenicu.bsky.social · last yr.

We are delighted to share @oscarkelly.bsky.social's brilliant development of synthetic chlorophyll mimics that provide insight into photosynthesis (with contributions from the excellent @marcelswart.bsky.social): pubs.acs.org/doi/full/10.... @researchireland.ie @tcddublin.bsky.social

Marcel Swart@marcelswart.bsky.social · last yr.

Check out our latest contribution in @jacs.acspublications.org, moved forward by Oscar Kelly doi.org/10.1021/jacs... With Brendan Twamley and @fenicu.bsky.social Cc @iqccudg.bsky.social

Electrostatic Fields Induce Accelerated Proton Coupled Electron Transfer Rates in Chlorophyll Model Compounds

Chlorophyll-based pigments are crucial mediators of redox processes in photosynthesis, serving as the primary electron donors in photosystems I and II. Despite their structural similarities, these pigments exhibit a wide range of redox potentials (0.5–1.3 V vs SHE), and little experimental insight into the origins of this variation is available. To address this deficit, we have synthesized two crown ether-appended Mg-porphyrin complexes as chlorophyll model compounds and demonstrated their ability to bind redox-inactive metal cations. Cation binding to the Mg-porphyrin complexes was found to increase their redox potentials in a manner that depends linearly on the total cationic charge felt by the complex, implicating a through-space electrostatic field effect. The corresponding 1-electron oxidized π-cation radical complexes were then prepared and characterized by UV–vis, FT-IR, and EPR spectroscopies and ESI-MS. The π-cation radical species were found to be competent for the PCET oxidation of a phenolic substrate, mimicking the reaction between photo-oxidized chlorophyll and tyrosine in photosystem II. Cation binding to the π-cation radical complexes was found to increase the rates of their PCET and ET reactions in a charge-dependent manner which could be rationalized using Marcus theory. This work provides direct experimental evidence that electrostatic fields can tune the redox potentials of chlorophyll model compounds, leading to an increase in their oxidative reactivity.

doi.org

Dan Sheehan@dansheehan.bsky.social · last yr.

Okay so imagine this, you have no opinions, you have no skills, you have no wants or desires, you are a smooth orb of nothing and our subscription service helps make sure you still cast a shadow that resembles a human being. Sounds sick right?

Bioinspired Inorganic Chemistry, Dublin@fenicu.bsky.social · 2y ago

@agnideep.bsky.social's mega-project on our efforts to develop catalytic fluorination of hydrocarbons is now published. Congrats Agni on an excellent effort!! #chemsky onlinelibrary.wiley.com/doi/10.1002/...

High‐Valent Cobalt‐Difluoride in Oxidative Fluorination of Saturated Hydrocarbons

Polyamine-supported CoII complexes catalyzed the oxidative fluorination of saturated hydrocarbons, in some instances selectively, when combined with Selectfluor and CsF, producing fluorinated product...

onlinelibrary.wiley.com