Linda Kvastad
@kvastad.bsky.social
PostDoc at Karolinska Institutet, Department of Cell and Molecular Biology. Spatial transcriptomics science adventures! "Well-being and mental health skills are human rights & of monumental importance to scientific excellence" @csi-initiative.bsky.social
We’re excited to share our new preprint: Spatial mapping of pediatric brain tumors across diagnoses and relapses A spatial transcriptomic atlas of 59 tumor sections from 19 patients, spanning nine major and rare diagnoses, including seven relapses, 🧵 Highlights:
Recently presented our work on how spatial transcriptomics + genetics can reveal putative causal tissue structures for complex traits. 📄 Preprint: doi.org/10.1101/2025... #spatialbiology #genomics #genetics @lifesciences-ge.bsky.social
New preprint! My (now former) postdoc @kvastad.bsky.social led this integration of GWAS and spatial transcriptomics (ST) data to identify tissue structures with enrichment of disease-implicated genes = likely causal drivers of disease biology. www.biorxiv.org/content/10.1...
Spatial transcriptomics and genetically implicated genes identify putative causal tissue structures for complex traits
Spatially resolved transcriptomics is transforming our understanding of cellular and molecular diversity of tissues. Here, to identify tissue structures that are enriched for putatively causal disease...
biorxiv.org