here's a mirror of what i could find of the tenderbutton blog on archive.org now made fast and searchable in one place including comments (some missing images in newer posts) molecular.beauty/tenderbutton... enjoy! #chemsky #chemchat
Tenderbutton — a reading archive
A readable preservation of the Tenderbutton chemistry blog and its comments.
molecular.beauty
If you're also going to the ACS, say hi. I'll be mostly at CINF.
We're still looking for candidates who are interested in working on an industry-relevant project in close collab with a major pharmaceutical company. It's a really nice opportunity for someone looking to transition to an industry position. #chemjobs #phdjobs #cheminformatics #bioinformatics
Chemical Biology Resources@chembl.bsky.social · 3w agoInterested in a 3-year Postdoctoral Fellowship developing our services, and working in collaboration with a major pharmaceutical company? Then checkout this blogpost, and get in touch asap: chembl.blogspot.com/2026/06/invi...
1/ Uber burned its entire 2026 AI budget by April. ServiceNow did the same. KPMG says U.S. orgs project $207M average AI spend over the next 12 months — nearly 2x last year. The all-you-can-eat era of AI coding tools is over. The deadline matters.
Visualize molecular orbitals and electron density easily with Avogadro 2.0. Volumetric rendering of orbitals, plus van der Waals, solvent-accessible and solvent-excluded surfaces for biomolecular work. See the chemistry, not just the atoms. #compchem #openscience #opensource
My column in Chemistry World reads a little differently this month:
‘The truth is supremely valuable and we cannot lie our way to it’
As a scientist with family in Iran, Derek Lowe finds his own government's approach to truth alarming
chemistryworld.com
The deadline for in-person registration for the upcoming ChEMBL UGM is 18th March so please register soon. It would be great to see you there. #chembl #cheminformatics #chemsky chembl.blogspot.com/2026/03/seco...
Second announcement of 2nd ChEMBL User Group Meeting
This is a reminder that the 2nd ChEMBL User Group Meeting will take place on June 10-11 on the Wellcome Genome Campus, Hinxton, near Cambri...
chembl.blogspot.com
Obviously a lot is going on (gestures widely) Amid chaos, I cope by doing *something* -- anything. Lately, it's been coding for @avogadro.cc because it feels like some small change I can do myself For *years* I've wanted to show electron density volumes .. little clouds ☁️☁️ #compchem
I'm publicising the ChEMBL UGM. There are various community members or organisations that maintain newsletters in the field of cheminformatics, but I'm not aware of them all. Andreas Bender has one, CICAG and CINF have more formal ones; are there others? #cheminformatics #CINF
Blogpost that looks at how LLMs have improved at 'reasoning' over time. This is a key capability that enables many scientific workflows. baoilleach.blogspot.com/2026/01/impr...
Improvement in reasoning performance of LLMs over time
If you tried using ChatGPT when it first came out and concluded it wasn't much use for a scientific reasoning task, it might be time to try ...
baoilleach.blogspot.com
A blogpost on changes to ChEMBL data deposition: chembl.blogspot.com/2026/01/chan... ...and not unrelated, a recent talk I gave on why data curation is needed and what it involves: github.com/chembl/prese...
Changes to ChEMBL Data Deposition
Over the years, ChEMBL has accepted 336 datasets deposited by the community. In fact, these data now comprise around 50% of the bioactivity ...
chembl.blogspot.com
Join the team!
Chemical Biology Resources@chembl.bsky.social · 8mo agoLast chance (closing dates Jan 11) to apply for open positions in the team: www.ebi.ac.uk/about/teams/... 1. Technical Lead for the team - could be someone with either a scientific or computing background. 2. NLP Data Scientist/Scientific Data Engineer, to develop a drug side effect resource
A blog post on "Classifying PubMed Abstracts with LLMs". baoilleach.blogspot.com/2026/01/clas...
Classifying PubMed Abstracts with LLMs
I've just spent the Christmas playing with the OpenAI API, and I am impressed at what is now possible. There are 38M PubMed Abstracts (*); t...
baoilleach.blogspot.com
The date for the ChEMBL UGM has been fixed for June 10-11 2026. The website is up at www.ebi.ac.uk/about/events... and registration opens in January. See you next year!
2nd ChEMBL User Group Meeting – EMBL-EBI Events
ebi.ac.uk
👉 Just 2 weeks left to apply to these positions in our team (AI Lab for Molecular Engineering) in Sweden. Come design polymers with us! To learn more about our team, please visit our group website: ailab.bio
Rocío Mercado Oropeza@rociomer.bsky.social · 9mo agoWe are currently recruiting 2 PhD students to work on AI-driven polymer design and engineering in my team at Chalmers as part of our @erc.europa.eu project POLYGEN. 💻🧪🇸🇪 Please spread the word and share to potentially interested candidates! Apply by: Dec 28, 2025 www.chalmers.se/en/about-cha...
My team has roles available for scientific developers either as Technical Lead (more senior) or as part of the development of a Side Effect Resource. baoilleach.blogspot.com/2025/12/open... #chemsky #chemjobs #bionformatics #cheminformatics #datascience #techlead
Openings for Scientific Developers in the Chemical Biology Services team
As part of a collaboration with Open Targets on the development of a Side Effect Resource to guide target selection, we have two positions a...
baoilleach.blogspot.com
Apply now! Or DM me if you have questions. This is a hands-on role managing the dev team responsible for #chembl, #chebi, etc. Looking forward to seeing who applies!
Chemical Biology Resources@chembl.bsky.social · 9mo agoWe are looking for a new Technical Lead for our group. This is an exciting opportunity for someone either from a scientific or informatics background to play a key role in our team which has a huge impact on the scientific communities that we serve: chembl.blogspot.com/2025/12/open...
Our new paper now 🎉 Published: Cheminformatics Microservice V3! Paper: doi.org/10.1186/s133... 🛠️ Web app + API: RDKit, CDK, Open Babel — NO install, 100% open-source. Try now: app.naturalproducts.net #Cheminformatics #OpenScience #Innovation #CompChem #Opensource
Cheminformatics Microservices UI
Cheminformatics Microservices UI - A modern interface for chemical data analysis
app.naturalproducts.net
We've just released a webinar that provides background on the #chembl database alongside worked examples highlighting some common scenarios in drug discovery initiatives. chembl.blogspot.com/2025/09/make...
Make the most of the ChEMBL interface with our newest webinar!
Before starting a new drug discovery project, it’s useful to compile existing data on compounds and targets of interest. Open access bioacti...
chembl.blogspot.com
I've gone from a review a year to being asked 6 times in as many weeks. The honeymoon period of returning to academia is well and truly over... :-)
We have gone back in time and generated SQLite files for all releases of #ChEMBL from version 1 onwards making it easier to carry out analyses across ChEMBL versions. chembl.blogspot.com/2025/09/sqli...
chembl.blogspot.com
Where's the best place to advertise a (computational) postdoc position? (asking for a friend...) #chemjobs #chempostdocs
Check out this opportunity to join my lab as a postdoc! www.ebi.ac.uk/research/pos... Every year, faculty from EMBL-EBI and the Wellcome Sanger Institute co-develop projects that allow fellows to be part of ✨both✨ of these amazing research institutes.
EMBL-EBI-Sanger postdoctoral fellowships (ESPOD)
The ESPOD fellowship builds on the collaborative relationship between EMBL-EBI and the Wellcome Sanger Institute, offering projects that combine experimental (wet-lab) and computational (dry-lab) appr...
ebi.ac.uk
Blog post on "A new job, a postdoc opportunity, an open biological curator role, and a user group meeting" baoilleach.blogspot.com/2025/07/a-ne...
A new job, a postdoc opportunity, an open biological curator role, and a user group meeting
Almost exactly 6 months ago, I took over the leadership of the Chemical Biology Services team at EMBL-EBI, Hinxton, UK. This is the team th...
baoilleach.blogspot.com
Selfie with @baoilleach.bsky.social in severe violation of CADD GRC policy 😀 Cool things are coming to ChEMBL, stay tuned 🤖
