A scientific community without (some critical mass of) virtuous scientists doesn't have the means to maintain this normative alignment. This idea is neither naive nor conservative. It has just been sidelined for being a fantasy (Probably due to the widespread allure of neoliberal fantasies).

Tempted to use AI to write your cover letter or email to a potential employer? RESIST! It is simultaneously obvious, insulting, and renders you totally undifferentiated from the other 80 people being considered t the same time. There has never been a better time to write concisely in your own voice!

Publicity photos in front of a blackboard of mathematics iare rarely a good look. Particularly rich individuals with political connections.

The dumbest preventable thing I do on a regular basis is that I tell people I'm almost done when I'm not almost done and/or not sure when I'll actually be almost done. I AM GOING TO STOP DOING THIS, STARTING TODAY. Thank you all for your support.

Why validate hundreds of R functions your project never uses? Litmus helps regulated teams focus validation on the functions their code actually depends on, with risk scoring, audit reporting and ongoing monitoring. www.jumpingrivers.com/litmus/ #RStats #Pharma #GxP

"Can we do this with AI?" is something I've heard a few times, without the person understanding either "this" or "AI".

Me: trying to get my ducks in a row My ducks:

🚀 A major milestone for @manifest-cirrp.bsky.social. Launching our prospective recruitment represents a significant milestone since we launched in Q4 2024. In doing so, we'll have the opportunity to learn from every patient. @ukri.org @crick.ac.uk 📖 Read more in The Christie press release: 1/4

Sandbach man is the first in the UK to join landmark immunotherapy study

Mark England was diagnosed with bladder cancer in early December last year. He is the first patient to join the MANIFEST study, one of the largest immunotherapy studies in the country.

christie.nhs.uk

Getting ahead of myself, but if England win in the final against France, do we get to keep the Bayeux tapestry?

Our ambition to combine artificial intelligence with fundamental biology and medicine continues to evolve as we welcome Mihaela van der Schaar as our Chief AI Scientist. Read more: www.crick.ac.uk/news/2026-06...

Mihaela van der Schaar appointed Crick Chief AI Scientist

The Francis Crick Institute has appointed Professor Mihaela van der Schaar as its Chief AI Scientist, advancing its ambition to combine artificial intelligence with fundamental biology and medicine, c...

crick.ac.uk

An international team of scientists, led by @charlesswanton.bsky.social lab at the Crick and @ucl.ac.uk and funded by @cancerresearchuk.org, have identified a signature of 14 proteins in the blood that can predict lung cancer risk over five years before diagnosis. www.crick.ac.uk/news/2026-06...

Maybe I’m biased, but I’m starting to think R is the best language for agentic engineering. #rstats cornball.ai/posts/cortez...

Middlemarch rightly in first place for “written in English”, but given this is for novels available in English, maybe it should come second to In Search of Lost Time. www.theguardian.com/books/ng-int...

The 100 best novels of all time

The top 100 novels of all time published in English, as voted for by authors, critics and academics worldwide. How many have you read?

theguardian.com

The people who think they are good at everything because they are good at coding are also bad at coding.

Don't you f**king dare.

“Learning without thought is labor lost; thought without learning is perilous.” — Confucius, Analects

🥁🎉The Psychosis Collective proudly presents our first preprint 𝐂𝐥𝐨𝐳𝐚𝐩𝐢𝐧𝐞 𝐬𝐮𝐩𝐩𝐫𝐞𝐬𝐬𝐞𝐬 𝐚𝐮𝐭𝐨𝐢𝐦𝐦𝐮𝐧𝐢𝐭𝐲 𝐝𝐫𝐢𝐯𝐢𝐧𝐠 𝐩𝐬𝐲𝐜𝐡𝐨𝐬𝐢𝐬-𝐥𝐢𝐤𝐞 𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐮𝐫 𝐢𝐧 𝐦𝐢𝐜𝐞 𝘈 𝘥𝘪𝘴𝘤𝘰𝘷𝘦𝘳𝘺 𝘫𝘰𝘶𝘳𝘯𝘦𝘺 𝘪𝘯 𝘵𝘩𝘳𝘦𝘦 𝘢𝘤𝘵𝘴 starring Le He & Harriet Feldman www.biorxiv.org/content/10.6... We wanted to understand how antipsychotics work. Thread🧵

Fascinating that Galileo's reputation as a "big ideas" scientist (and they don't get much bigger than Galilean relativity, principle of equivalence, and light having a speed) can be broadened by the finding he was also on top of the details/maths. www.science.org/content/arti...

Galileo’s handwritten notes found in ancient astronomy text

Discovery sheds new light on how famed astronomer came to lead a scientific revolution

science.org

Except literally every data analysis or model I've ever asked AI to build has contained at least one error: www.nature.com/articles/d41... Common response: "But someone just needs to give AI detailed instructions..." But who is the "someone" in that sentence? And how did they get their expertise?

I'm so excited to announce the first release of my newest #Rstats package, {adrftools}! This package facilitates estimation, visualization, and testing for the causal effect of a continuous (i.e., non-discrete) treatment. 🧵 1/10 #statssky #episky #causalinference

adrftools: Estimating, Visualizing, and Testing Average Dose-Response Functions

Facilitates estimating, visualizing, and testing average dose-response functions (ADRFs) for characterizing the causal effect of a continuous (i.e., non-discrete) treatment or exposure. Includes suppo...

cran.r-project.org

Job offer: PhD-level biostatistician with ML&omics experience to work on prediction models for CAR T cell therapy, in an exciting clinical trial - spatial omics - data science consortium (LOOP/INTeRCePT3.0 centered in Zurich; this position in Heidelberg) embl.wd103.myworkdayjobs.com/en-GB/EMBL/j...

“It is a fault to wish to be understood before we have made ourselves clear to ourselves.” — Simone Weil, Gravity and Grace

Hannah Arendt did not mince words, did she? 'Totalitarianism replaces all first-rate talents with crackpots and fools whose lack of intelligence and creativity is still the best guarantee of their loyalty.' From "The Origins of Totalitarianism" (1951)

“Selfish — a judgment readily passed by those who have never tested their own power of sacrifice.” — George Eliot, Silas Marner

Would love to see more people on LinkedIn with 'non-strategic leader and non-systems thinker' in their bio. Like, just really focused on tactical execution and solving specific things reliably.

Last Christmas I gave you my heart. The very next day You gave it a weigh.

Craig M. Ranapia@craigmranapia.bsky.social · 9mo ago

Last Christmas I gave you my heart. The very next day You tore it apart.

Cool. Classical billiards can compute - but only "for some value of billiard table" I think. arxiv.org/abs/2512.19156

Classical billiards can compute

We show that two-dimensional billiard systems are Turing complete by encoding their dynamics within the framework of Topological Kleene Field Theory. Billiards serve as idealized models of particle mo...

arxiv.org

I cannot be trusted to attend a meeting without a calendar invite

MIT's famous 'Missing Semester' course (for the Independent Activities Period in January is back. missing.csail.mit.edu/2026/