My kingdom for a reference manager that maintains proper italicization of gene and species names.

New paper that includes work from one of my first grad students (Aaron) and one of my most recent (Chris). Experimental evolution really is the gift that keeps on giving. Mutational bias and local genome context constrain adaptive paths in experimental evolution academic.oup.com/genetics/adv...

Great fun as always at the @uwgenome.bsky.social retreat, this year on Bainbridge Island (photos from the ferry this morning). Very stimulating talk on the history of the concept of inheritance by @matthewcobb.bsky.social And i feel compelled to share my favorite poster judging method for retreats:

Exciting news: @uwgenome.bsky.social will be hiring for two tenure-track faculty positions this year, one open rank and one assistant professor. Both are “Genome Sciences” interpreted broadly so we welcome applicants working in a variety of fields and methods. Ad will be out shortly.

Seattle locals request: does anyone have a set of "port tongs" that I could borrow for what I promise is a very highly scientific cause?

Lab outing to a Mariners game

The @c4lifesciences.bsky.social is seeking an Executive Director. CLS is a terrific group of engaged scientific & scholarly society leaders. Check out the position (ideal for a person experienced in policy & advocacy + Capitol Hill) & share w/interested, qualified folks.

Executive Director, Coalition for the Life Sciences - American Society for Cell Biology (ASCB) - Career Page

Apply to Executive Director, Coalition for the Life Sciences at American Society for Cell Biology (ASCB) in Bethesda, MD.

ascb.applytojob.com

Is there anything better than hanging out with a room full of people who geek out about yeast as much as a yeast geneticist? Got invited to be the guest of the Rat City Homebrew Club, who is planning some experiments with S. eubayanus. Ran out of yeast stab vial party favors.

One fun thing at the Botstein symposium was being reminded of this great article about the novelist Jeffrey Eugenides visiting the lab to get some "spice" for The Marriage Plot. I can literally hear David say "I have here a novelist” when he brings him into the lab. www.nytimes.com/2012/02/14/s...

The Scientist Was a Figment, but His Work Was Real (Gift Article)

Jeffrey Eugenides’s new novel, “The Marriage Plot,” has scenes describing yeast genetic studies that ring so true, many assume that researchers had to have given him some in-depth help.

nytimes.com

Welcome to our new graduate student, Joey! He is a student in the School of Environmental and Forest Sciences co-mentored with @clairewilling.bsky.social. I'm excited and a bit intimidated to move On Beyond Ascomycetes. Auditing Claire's Fungal Ecology & Biology class this quarter to get up to speed

Emotional and meaningful day celebrating and remembering the legacy of David Botstein. pph.princeton.edu/david-botste...

David Botstein Memorial Symposium

pph.princeton.edu

If you are thinking of applying to the @uwgenome.bsky.social PhD program this fall, we have a couple of zoom info sessions set up for Oct 6 and Oct 22. Please register at the link. Our website also has a ton of useful information about crafting your application. www.gs.washington.edu/news/graduat...

Latest w/ Bonny Brewer and Raghu. We evolved different DNA repair mutants to investigate the mechanism of a gene amplification we've been working on for many years. We got all sorts of interesting alternate outcomes, including these cool subtelomeric repeats in Ku mutants dx.plos.org/10.1371/jour...

Telomeric amplicons of SUL1 and Y’ in yeast are generated by microhomology-mediated break induced replication occurring in cis

Author summary The human genome is peppered with repeated segments that are located at sites both nearby and distant from the original, ancestral segments. These Copy Number Variants, or CNVs, appear ...

dx.plos.org

Updated version of our preprint about mutations in URA6 causing 5-FOA resistance in S. cerevisiae, now including new metabolite profiling data! www.biorxiv.org/content/10.1...

URA6 mutations provide an alternative mechanism for 5-FOA resistance in Saccharomyces cerevisiae

The URA3 gene is frequently used in the budding yeast community as the mutation target for 5-fluoroorotic acid (5-FOA) resistance. We identified a class of ura6 mutants that can grow in the presence o...

biorxiv.org

About to attempt a live demo on yeast strain development at @brewingchemists.bsky.social 2026 meeting. Wish us luck!

Our deep mutational scan of G6PD is out in final form! @reneegeck.bsky.social did an incredible job on the project, & @dougfowler.bsky.social has been fantastic to collaborate with, as usual. Really gratifying to contribute functional evidence on VUS classification for G6PD deficiency. rdcu.be/fyTlf

Favorite hilarious thing I learned today: we borrowed a plate reader from a lab downstairs and they have two, named Jacob and Edward. They’re both apparently temperamental and people have superstitious favorites. Edward gave us an error so I guess we’re Team Jacob. So funny.

Join @FredHutch.org's Basic Sciences Division as an Assistant or Associate Professor and help shape the future of fundamental biology. We welcome applicants whose work will complement, extend, or bring new directions to the division.

If anyone would like to join me in a last-gasp-of-summer attempt to catch up on things before the new school year hits, I'm calling August #FrogMonth during which I'm going to try to polish off as many proverbial Twainian frogs as possible. Moldering papers, overdue administrative tasks, & more 🐸🐸🐸

Looking forward to our annual Wednesday Evening at the Genome Public Lecture tonight, this year in partnership with @burkemuseum.bsky.social: Samuel Wasser on using genetics to combat the illegal ivory trade. For future events, sign up for our mailing list mailman11.u.washington.edu/mailman/list...

At the Hutch today for a teacher training workshop with @sciedhutch.bsky.social New group of teachers trying out our yeast evolution and genomics high school activities as part of our @yevolab.bsky.social project. You can download materials from yevo.org (and we can send you strains too!)

Congratulations to undergraduate researchers Katya and Nya on winning Herschel & Caryl Roman Scholarships! www.gs.washington.edu/academics/aw...

Got myself some new business cards from the wonderful Letterpress pdx!

Join the Pacific Northwest Yeast Club for the 2026 PNWYC annual meeting! July 31st, 2026 at Western Washington University, Bellingham, WA. Registration's FREE. Anyone working in any type of fungal system is welcome! www.pnwyc.net/home

Registration is open for the 2026 PNW Yeast Club meeting, July 31 at WWU in Bellingham. Researchers in any yeast/fungal systems welcome. Register by July 10 for talks, or July 24 for posters & other attendees. Thanks @dan-pollard.bsky.social and @kinasequeen.bsky.social for hosting! www.pnwyc.net

PNWYC

PNWYC 2026 Meeting A day for yeast labs in the Pacific Northwest to get together and share research, outreach, teaching, and more! July 31, 2026, in Bellingham, WA, USA Western Washington University ...

pnwyc.net

Weekday Jokes@weekdayjokes.bsky.social · 10mo ago

The Yeast Club meeting is called to order. All rise

End of spring quarter we said goodbye to newly graduated PhD student Gabby, and now beginning of summer we say hello to summer REU student Diana!

The @genetics-gsa.bsky.social Yeast Meeting will always be my favorite. Highlights: grad student Leah winning best poster (!), postdoc Sarah's poster on a new @yevolab.bsky.social evolution scheme, Barbara's talk on beer yeast evolution, Leah's real time data analysis on the mentoring panel #Yeast26

Building on a series of successful virtual meetings, members of GSA's Department Chairs Forum gathered at Asilomar for their first in-person meeting which provided a space for peer-level exchange on navigating a rapidly-shifting landscape and addressing challenges. ⬇️🧵

Dunham lab past and present at #Yeast26 ! @maitreya.bsky.social

Graduate awardees of #Yeast26 YGM Student Poster Awards announced by #InesPinto @uarkansas.bsky.social: #LeahAnderson @maitreya.bsky.social lab @uwgenome.bsky.social, #NasimaAkhter @justinfay.bsky.social lab @urochester.bsky.social , & #OnyinyechiOnuoha #BruceKnutson lab @biochemdept-bmb.bsky.social