Join @FredHutch.org's Basic Sciences Division as an Assistant or Associate Professor and help shape the future of fundamental biology. We welcome applicants whose work will complement, extend, or bring new directions to the division.

Join us for Jodiene Johnson's defense! Title: Determining a mechanism for the synthetic lethal interaction between the DNA repair proteins BRCA2 and SCAI Lab: Adeyemi Lab, FH When: Friday, August 14, 11:00 a.m. PDT Where: FH O'Mack Suite (Steam Plant Building) & Zoom (email mcb@uw.edu for link)

Gabriel Spitzer (@kuow.org) visited our lab to learn about our work to use evolutionary principles to supercharge innate immunity to (hopefully) deploy it in the face of viral infections. Gabriel is a masterful storyteller and would recommend listening to his ‘Pocket Science’ series (each ~12 min)

Fred Hutch@fredhutch.org · 2w ago

Our immune systems have evolved to overcome all kinds of flus, plagues and poxes, but the process of adaptation is slow. @basicsci.fredhutch.orgs' @harmitmalik.bsky.social looks to find ways to put evolution into overdrive to fight future diseases. 🎧 Listen to @kuow.org's Pocket Science for more.

Last Wednesday I had the immense privilege of defending my PhD dissertation @fredhutch.org @basicsci.fredhutch.org. The last 6 years in Seattle have been the most joyous of my life, and I am so grateful to have been surrounded by amazing people that made this not only possible, but wonderful! 1/

Dr. @harmitmalik.bsky.social chats with Gabriel Spitzer on Pocket Science from @kuow.org where he discusses his lab's work in Basic Sciences @FredHutch.org using the genetic echoes of long-dead viruses to help pinpoint defenses against whatever virus comes next.

Pocket Science

Discovery is happening all around Seattle… if you know where to look.

kuow.org

Join us for Emily Teets’s (@eteets.bsky.social ) dissertation defense! Title: Investigating the role of glial pruning in Parkinson's Disease Lab: Singhvi Lab, FH When: Monday, August 3, 1:00 p.m. PDT Where: FH Pelton Auditorium (Weintraub Building) & Zoom (email mcb@uw.edu for link)

Our immune systems have evolved to overcome all kinds of flus, plagues and poxes, but the process of adaptation is slow. @basicsci.fredhutch.orgs' @harmitmalik.bsky.social looks to find ways to put evolution into overdrive to fight future diseases. 🎧 Listen to @kuow.org's Pocket Science for more.

An evolutionary arms race - Pocket Science

Gabriel Spitzer talks to Harmit Malik about using the remains of dead viruses that have built up in our bodies to create new variants to target future viruses.

omny.fm

Congratulations to Dr. Steve Hahn on being elected to the Washington State Academy of Sciences! A well-deserved recognition of his scientific leadership, mentorship, and contributions to advancing science in Washington.

New Members Elected to Washington State Academy of Sciences - Washington State Academy of Sciences

SEATTLE, WA – The Washington State Academy of Sciences (WSAS) announced today the election of 30 new members in recognition of their outstanding record of scientific and technical achievement and…

washacad.org

The remarkable @jeremyahollis.bsky.social defended his PhD thesis on the evolutionary innovations and landscapes of integrin proteins from Melody Campbell & Malik labs today to a packed house @fredhutch.org @basicsci.fredhutch.org Jeremy is a force of nature & one of the kindest people I’ve ever met

“Scents and Sense-ability” We’re excited to have Dr. Denise Ferkey speaking at a special scientific seminar today at noon. For all our @FredHutch.org colleagues, don’t miss a great talk in the Sze East room of the Thomas Building!

Open science before it had a name: An interview with molecular biologist Steven Henikoff (who is not on social media) @fredhutch.org @basicsci.fredhutch.org @hhmi-science.bsky.social @natprot.nature.com www.springernature.com/gp/researche...

This was nothing short of a delight to work on with an amazing set of collaborators. Forever grateful to @basicsci.fredhutch.org at @fredhutch.org for making science so accessible and joyous to do!

Harmit Singh Malik@harmitmalik.bsky.social · last mo.

Jeremy Hollis’ detective story on centromeric histone chaperones (HJURP/Cal1) is now published after peer review with a few extra goodies. @jeremyahollis.bsky.social @nlehrbach.bsky.social @cbmoens.bsky.social @irinakitop.bsky.social @basicsci.fredhutch.org www.science.org/doi/10.1126/...

Jeremy Hollis’ detective story on centromeric histone chaperones (HJURP/Cal1) is now published after peer review with a few extra goodies. @jeremyahollis.bsky.social @nlehrbach.bsky.social @cbmoens.bsky.social @irinakitop.bsky.social @basicsci.fredhutch.org www.science.org/doi/10.1126/...

Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

Animals encode a rapidly evolving, essential cell cycle gene previously thought to be absent.

science.org

Jeremy Hollis@jeremyahollis.bsky.social · 5mo ago

We have some genetic sleuth work to share with you! What started as a rotation project turned into nothing short of an amazing collaboration between 4 labs in the zoo that is @basicsci.fredhutch.org. We found an essential histone chaperone long thought to be missing in most animals 🕵️‍♂️ bit.ly/4uf8sxz

High schoolers doing chromatin profiling? @FredHutch.org's Dr. Steve Henikoff explains how open science tools are being used to teach the next generation of scientists. Interview with @springernature.com:

Open science before it had a name: An interview with molecular biologist Steven Henikoff | For Researchers | Springer Nature

Dr. Steven Henikoff shares his experiences of how sharing protocols enables other people to use a method you develop, and how this moves the

springernature.com

Training the next generation of scientists is critical for future scientific and medical breakthroughs. The Basic Sciences Postdoctoral Fellowship Award was established by Dr. Steve Hahn to support outstanding postdocs at Fred Hutch Basic Sciences. Apply now:

Basic Sciences Postdoctoral Fellowship Award

The Basic Sciences Postdoctoral Fellowship Award was established in 2026 to honor and support outstanding postdoctoral trainees, based primarily on their initial postdoctoral work at Fred Hutch.

fredhutch.org

When Neuroligin2 sticks around, #astrocytes take shape. Sneha Ray and Aakanksha Singhvi @singhvilabglia.bsky.social @basicsci.fredhutch.org discuss work from Sakers, @caglaeroglu.bsky.social et al. (rupress.org/jcb/article/...), in Spotlight: rupress.org/jcb/article/... #Neuroscience

"When you work on methods, they're only really successful if someone else uses them." @FredHutch.org's Dr. Steve Henikoff on why open science has always been the best way to do research. A must-read interview with @SpringerNature.com:

Open science before it had a name: An interview with molecular biologist Steven Henikoff | For Researchers | Springer Nature

Dr. Steven Henikoff shares his experiences of how sharing protocols enables other people to use a method you develop, and how this moves the

springernature.com

Dr. @irinakitop.bsky.social, a senior staff scientist in the Basic Sciences Division at Fred Hutch, is the first winner of the Genetics Society of America Mentorship Award who isn’t a principal investigator or faculty member. Read more: https://bit.ly/4epmdnD

www.fredhutch.org/content/www/... Ladies and gentlemen... the amazing @irinakitop.bsky.social !

Fred Hutch senior staff scientist honored by Genetics Society of America

Dr. Irini Topalidou, a senior staff scientist at Fred Hutch Cancer Center, is the first winner of the Genetics Society of America Mentorship Award who isn’t a principal investigator or faculty member....

fredhutch.org

"Open science before it had a name." @FredHutch.org's Dr. Steve Henikoff has been doing it for 50+ years! Read @springernature.com how he helped shape modern genomics and pushed for more open scientific practices:

Open science before it had a name: An interview with molecular biologist Steven Henikoff | For Researchers | Springer Nature

Dr. Steven Henikoff shares his experiences of how sharing protocols enables other people to use a method you develop, and how this moves the

springernature.com

Lee Hartwell, director/president emeritus @fredhutch who's @uwmedicine.bsky.social & Fred Hutch work on cell cycle regulators earned him a 2001 #NobelPrize, talks about the rise of yeast as a model organism in biology with The Scientist's Laura Tran

The Rise of Yeast as a Model Organism in Biology | The Scientist

Yeast’s emergence as a model organism reshaped scientific discovery in cell biology, genetics, and more.

tinyurl.com

Congrats to Adam Nguyen and Jeremy Hollis @jeremyahollis.bsky.social !!

Today we're celebrating the achievements of three Basic Sciences Faculty! Dr. Jesse Bloom (@jbloomlab.bsky.social) for being elected to the @nasonline.org, Dr. Susan Parkhurst for being named a Fellow of @aaas.org, and Dr. Toshio Tsukiyama for being appointed to the Lycette Endowed Chair.

We have two great talks lined up for the final Friday Afternoon Seminars of the season! For everyone @FredHutch.org, join us at 4:00 in Pelton to hear about the latest discoveries from Yulong Su in the Eisenman Lab and Joy Chen in Human Biology’s @behnamnabet.bsky.social Lab.

Last week's fantastic seminar by Prof. Harmit Malik, "Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins", can now be viewed on CPGE's YouTube channel! youtu.be/VxSppXrqGfI #chromatin #genomics #evolution #northwestern #genomics #proteins #dna #fredhutch

Harmit Malik- Genetic Conflicts Drive The Unexpected Rapid Evolution Of Essential Chromatin Proteins

YouTube video by Center for Physical Genomics and Engineering

youtu.be

This year we presented a special introduction to the Weintraub Award Symposium featuring colleagues of Dr. Hal Weintraub telling stories about what made Hal such an exceptional scientist, mentor, collaborator, and friend. You can watch it here:

Harold M. Weintraub Graduate Student Award Symposium Introduction

This is "Harold M. Weintraub Graduate Student Award Symposium Introduction" by Fred Hutch Cancer Center on Vimeo, the home for high quality videos and the people who love them.

vimeo.com

We are so incredibly excited to kick off the 2026 Weintraub Graduate Student Award Symposium today at 9 AM! It’s going to be a phenomenal day of talks and celebration of the outstanding achievements of the awardees.

Excited for an extra special Friday Afternoon Seminars on a THURSDAY! For everyone @FredHutch.org, don’t miss two fantastic talks today at 4:00 from Saket Mishra in the Hahn Lab and Rasika Venkataraman in Human Biology’s S. Lee Lab.

“Preprints: communicating at the speed of science” We’re thrilled to have @richardsever.bsky.social joining us from @openrxiv.bsky.social to speak at today’s Basic Sciences Division Guest Seminar. For all our @FredHutch.org colleagues, don’t miss a great talk at 11:30 in the B-suites.

Congrats to @basicsci.fredhutch.org's Dr. Jesse Bloom @jbloomlab.bsky.social on being elected to the National Academy of Sciences! He joins 120 newly elected members recognized for their distinguished and continuing achievements in original research. www.nasonline.org/news/2026-na...