Smart microscope platform PyCLM controls stimulation & imaging – showcased with optogenetic controlled EGFR to direct tissue movement 📹 Harrison R. Oatman et al @toettch.bsky.social lab @princeton.edu in @cp-cellsystems.bsky.social ➡️ bpod.org.uk/archive/2026... with @antdlewis.bsky.social
Biomedical Picture of the Day BPoD
@bpodaily.bsky.social
Biomedical Picture of the Day: daily intriguing images from global research. IMAGE/RESEARCH EXPLANATIONS AND LINKS TO THE PAPER on bpod.org.uk Supported by @leicamicrosystems.bsky.social & @oxfordbiochemistry.bsky.social, @ox.ac.uk
Age Related: Secretory proteins modulate over C.elegans life - ACP7 (we have similar) increases with age & boosting it extended worm lifespan 📸 Jason W. Miklas et al @brunetlab.bsky.social @stanford.edu in @cp-cellreports.bsky.social ➡️ bpod.org.uk/archive/2026...
Neuron detail over a wide field using @leicamicrosystems.bsky.social's Viventis Scape microscope 📹 by Dr Nick Gatford @kavlioxford.bsky.social made in the Micron Imaging Facility @oxfordbiochemistry.bsky.social ➡️ Read more on bpod.org.uk/archive/2026... with John Ankers
Bidirectional organisation of actomyosin network drives invagination & shaping study in sea squirt Ciona shows – insights for tube & lumen development 📸 Jinghan Qiao & Pengyu Yu et al, Ocean University of China & @tsinghuauniversity.bsky.social in @elife.bsky.social ➡️ bpod.org.uk/archive/2026/10/9
BPoD | Tube Organiser
Tube Organiser - Biomedical pictures for October 2026.
bpod.org.uk
Windows on Windows: Super-Resolution Optical Sectioning Microscopy allows blood vessel pores to be examined in situ 📸 Jasmin C. Schürstedt-Seher et al Biomolecular Photonics, Bielefeld University in @biorxivpreprint.bsky.social ➡️ bpod.org.uk/archive/2026... + @antdlewis.bsky.social
Computer modelling in pancreatic organoids reveals the pressures & processes leading to lumen development 📹 Byung Ho Lee et al @anne-grapin.bsky.social lab Max Planck Institute of @mpi-cbg.de in @natcellbio.nature.com ➡️ bpod.org.uk/archive/2026...
Differential incidence of microproteins in normal & Alzheimer's patient cortex reveals roles in neurodegeneration 📷 Brendan Miller et al @alansaghatelian.bsky.social lab @salkinstitute.bsky.social in @natureportfolio.nature.com Nature Aging ➡️ bpod.org.uk/archive/2026... with @rooph.bsky.social
KRAS gene variant KRASG12D drives distinct pathways causing abnormal lymphatic vessel enlargement or disruption of lymphatic valve formation 📷 Lorenzo M. Fernandes & Jeffrey Tresemer et al UT Southwestern Medical Center in & on cover of @dmmjournal.bsky.social ➡️ bpod.org.uk/archive/2026...
Laser-free super-resolution microscopy with inside live cell chemical reaction electrochemiluminescence 📸 Wenxin Zhu , Chi Zhang & Jiahui Gui et al, Zhejiang University in @nature.com ➡️ bpod.org.uk/archive/2026... with @antdlewis.bsky.social
Bugs Against Toothache: Gum disease-causing bacteria Porphyromonas gingivalis in contact with sensory neurons suppress pain perception 📷 Sena Chung & Doyun Kim et al Seoul National University in @science.org Advances ➡️ bpod.org.uk/archive/2026...
Eating the Dead: E-cadherin keeps epithelial cells together and equips them for devouring cellular debris 📷 Hanna-Maria Häkkinen, Marta Batet & @laurafbianchi.bsky.social et al @crg.eu in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026... with @rooph.bsky.social
Banking the Deposits: Atherosclerotic plaques characterised in patients undergoing surgery for atherosclerotic disease launches the AtherOMICS biobank study 📷 Luka Živković et al @mariosgeorgakis.bsky.social lab @lmu.de in @science.org Advances ➡️ bpod.org.uk/archive/2026...
Current Affairs: Tissue flow creates mechanical cues to coordinate immune-cell migration during development 📹 Hoang Anh Le et al @mayorlab.bsky.social @ucl.ac.uk @natcellbio.nature.com ➡️ bpod.org.uk/archive/2026... with @antdlewis.bsky.social
Raised Tep3 – orthologue of human CD109 – in fly cancers reduces the macrophage-dependent anti-tumour immune response 📷 Yoshiki Sakai & Kavya Adiga et al @bilderlab.bsky.social @ucberkeleyofficial.bsky.social in @science.org Advances ➡️ bpod.org.uk/archive/2026...
Fly model shows impact of human RYR1 gene variant on fly muscle development – establishing screen to glean consequences of other human variants @leicamicrosystems.bsky.social 📷 Monika Zmojdzian & Teresa Jagla et al Université Clermont Ferrand in @elife.bsky.social ➡️ bpod.org.uk/archive/2026...
The ovary actively 'counts' its eggs, preparing the same proportion for ovulation, at different stages of life 📹 Arturo D’Angelo et al @bokelab.bsky.social @crg.eu in @nataging.nature.com ➡️ bpod.org.uk/archive/2026... with John Ankers
Model of neuro-cardiac junctions by fusing a neuronal organoid with heart muscle cells reveals details underlying irregular heartbeats 📹 Lennart Valentin Schneider & Michael Gani Setya et al University Medical Center Göttingen in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026...
Schwann Song: Distinguishing terminal Schwann cells (tSC) from the myelinating kind reveals tSC don't affect neuromuscular junctions 📷 Hyun Kim, Seon-Yong Kim, Kyusang Yoo et al Seoul University in @elife.bsky.social ➡️ bpod.org.uk/archive/2026... with John Ankers
Long Distance Information: cis-regulatory elements identified genome-wide using combo of bulk with single-nucleus sequencing 📷 @gillian-forbes.bsky.social, Emilia Skafida & Irene Karapidaki et al @ensdelyon.bsky.social in @elife.bsky.social ➡️ bpod.org.uk/archive/2026...
Revelations from HiP-CT scanning on the nerve connections of the clitoris and surroundings 📸 Ju Young Lee et al, de Bakker lab @amsterdamumc.bsky.social in @biorxivpreprint.bsky.social ➡️ bpod.org.uk/archive/2026... with John Ankers
Atherosclerosis-affected arteries have abnormal immune tissue that produces autoantibodies promoting the atheromatous plaques 📸 C Zhang, Xi Zhang, Yi Ran, Z Wang, A J. R. Habenicht & Changjun Yin et al, Sun Yat-sen University in @natcardiovascres.nature.com ➡️ bpod.org.uk/archive/2026...
Upholding the Jaw: Role of the lymphatic system in arthritic and painful joints revealed – presenting a therapeutic avenue 📹 Yang Shu et al @usc.edu in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026... with John Ankers
A combo of X-ray μCT & photoluminescence spectroscopy with a 3D surface mesh for spatial registration to measure micro-cracks in teeth 📷 Irma Dumbryte et al Institute of Dentistry, Faculty of Medicine, Vilnius University in @elsevierconnect.bsky.social Measurement ➡️ bpod.org.uk/archive/2026...
Hold Your Nerve: Spectrin protein helps stabilise the nervous system in nematodes – hints at role for human spectrin impairment in neurological disorders 📷 @seancoakley.bsky.social et al The University of Queensland in @science.org Advances ➡️ bpod.org.uk/archive/2026... with John Ankers
Two-way mitochondrial transfer between GBM tumour cells & astrocytes via nanotubes – a tumour adaptation that could be targeted 📹 Ines Saenz-de-Santa-Maria et al, @pasteur.fr @upcite.bsky.social in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026...
Buried Treasure: Nanoscale organelle architecture & molecular distribution revealed in thick brain tissue sections - eg. here, morphology of individual dendritic spines 📸 Hao-Cheng Gao & Fan Xu et al Purdue University in @natcomms.nature.com ➡️ bpod.org.uk/archive/2026... with John Ankers
Streamlining large cryo-electron tomography montages using a workflow called MOSAIC in conjunction with MontageMaker merging software 📹 @rkhylton.bsky.social et al @raunser-lab.bsky.social, Max Planck Institute of Molecular Physiology in @cp-structure.bsky.social ➡️ bpod.org.uk/archive/2026...
Manipulating Maturity: Protein PRDM16 regulates human iPSC-derived cardiomyocyte maturation – potential target in heart damage repair & heart tissue engineering 📷 Kanae Tani et al Kyoto University in @stemcellreports.bsky.social ➡️ bpod.org.uk/archive/2026... with @rooph.bsky.social
Laminin LAMB4 is vital for sensory neuron development & survival – insight for treatment of peripheral neuropathies 📷 @kenyisama.bsky.social & Tripti Saini et al Zeltner lab @universityofga.bsky.social @dev-journal.bsky.social ➡️ bpod.org.uk/archive/2026...
Using click chemistry to snap the class of combo therapy called antibody-drug conjugates together makes them more effective 📷 Shayla Shmuel. Article: Cristina Simó et al @washumedicine.bsky.social in @nature.com ➡️ bpod.org.uk/archive/2026... with @rooph.bsky.social