Ten years ago, our director, Stefan Jentsch, passed away. A memorial symposium will be held in his honour on October 23. Many of his former colleagues and friends will be in attendance. Would you like to join? Please register until October 1: ❕https://eveeno.com/256035281 #Ubiquitin #Symposium
Structure
@cp-structure.bsky.social
Structure is a @cellpress.bsky.social journal publishing cutting-edge research across the full spectrum of structural biology.
Every electron counts⚛️! Researchers have determined the structure of the protein rubredoxin at an unprecedented 0.43 Ångström resolution. The method could now allow routine quantum crystallography of biological macromolecules. 👇More about this major advancement: www.mpinat.mpg.de/5314392/rn_2...
A sad day. Ada's pioneering work on the ribosome changed how we understand one of the central machines of life. She is a remarkable example of curiosity and boldness in pursuing questions that seemed impossible. Her scientific courage and persistence has been an inspiration.
Prof. Ada Yonath, Nobel Laureate and a Model of Scientific Perseverance, Has Passed Away - Weizmann Wonder Wander - News, Features and Discoveries
From pursuing an impossible dream to uncovering one of the cell’s best-kept secrets and advancing the design of improved antibiotics
wis-wander.weizmann.ac.il
How do African trypanosomes regulate the complement system? Check out our new study from @BiochemCook, in which he identified a new trypanosome receptor which binds to the core C3bBb convertase of the complement system and blocks its activity. Real all about it! doi.org/10.64898/202...
We posted a new preprint, Prot-LAMBDA. Unlike most protein language models, it is a pLM with an explicit encoding of protein structures. Strong performance in structure-related tasks including structure prediction. www.biorxiv.org/content/10.6...
It's out in @cp-structure.bsky.social! A fun process sorting out this puzzle with everyone in the @danengw.bsky.social group at NYUSoM! www.cell.com/structure/ab...
Structures of the human sodium-citrate cotransporter NaCT with and without substrates
Uptake of citrate by human NaCT is driven by a sodium gradient. Its sodium-substrate coupling mechanism is unclear. Sauer et al. determined cryo-EM structures of the protein in apo, in sodium, and in ...
cell.com
Incredibly proud of Messi Haile @mehsehret.bsky.social, a founding member of the Ho Lab, for her beautiful work uncovering the inner workings of a central piece of the malaria parasite invasion machinery: the malarial moving junction, out today in @cellpress.bsky.social! tinyurl.com/4p3md2eb 🦠❄️🔬
The abstract deadline for #CS3Dbiologicalfunction26 has been extended to July 27, 2026. Join leading researchers for cutting-edge science and networking with keynote speakers Suliana Manley, Stefan Raunser, and Feng Shao. http://dlvr.it/TTRB1C
I’ve been really excited by conferences that aim to combine techniques across scales, as I think it’s what’s current and future for #structbio. If you get excited by the same, here is an upcoming structural biology/computation/imaging conference at Keystone 👇🏾
Check out our latest work! AlphaFold 3 revealed a transient immune receptor complex that eluded biochemical studies for almost a decade 🤯 We describe a conserved structural logic underlying sensor–helper communication in an NLR immune receptor network 🧵👇
A conserved structural logic underlies sensor-helper NLR communication in the NRC immune receptor network https://www.biorxiv.org/content/10.64898/2026.05.18.725810v1
1/6 🧪 Big news for structural biology and AI: PDBe is now AI-native. We’ve built MCP Servers that connect the Protein Data Bank in Europe and the Alphafold Protein Structure Database directly to Claude and other MCP-compatible AI systems. Here’s what that unlocks 👇
The genome of ebola virus contains instructions for building seven proteins, which assemble with the genomic RNA to form one of the deadliest viruses. More at PDB-101:
PDB101: Molecule of the Month: Ebola Virus Proteins
Structures of ebola virus proteins are giving new hope for fighting this deadly virus
pdb101.rcsb.org
May is National Pet Month. Cats Iris (tortoise) and Ares (grey) help RCSB PDB's Ezra Peisach manage the PDBx/mmCIF Dictionary and preparations for the upcoming transition to extended PDB IDs and the new Beta Archive www.rcsb.org/news/fe...
We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better. Preprint: www.biorxiv.org/content/10.6... Code: github.com/warpem/miss-... 🧶 Thread:
Out today - structure of the human HIRA histone chaperone complex bound to nucleosomes. Ever wondered how nucleosomes are assembled in the wake of transcription? It takes a 'hulk of a protein complex'. Work by the amazing Wei Tian weetian558.bsky.social. www.biorxiv.org/content/10.6... 🧵
Join us in China for the Cell Press Symposia: Biological function in 3D: Structure, dynamics, and AI in partnership w/ SUSTech. Explore how emerging tech & AI reveal biology from molecules to organisms. #CS3Dbiologicalfunction26 http://dlvr.it/TS2xnP
Join us in China for the Cell Press Symposia: Biological function in 3D: Structure, dynamics, and AI in partnership w/ SUSTech. Explore how emerging tech & AI reveal biology from molecules to organisms. #CS3Dbiologicalfunction26 http://dlvr.it/TS2xnw
Cell Press: Championing real-world impact. www.cell.com/about?utm_so...