Go Carleigh! www.bostonglobe.com/2026/08/30/m...

Can a progressive overtake two center-left Democrats in N.H.’s 1st Congressional District race? - The Boston Globe

While the establishment-backed top contenders, Stefany Shaheen and Maura Sullivan, are locked in a close contest, a progressive push by Carleigh Beriont may be gaining momentum.

bostonglobe.com

📰 Hot off the press from the Xue & Sontheimer labs 🧬: Prime assembly enables precise genomic insertions up to 11 kb in cells, providing a universal strategy to correct many pathogenic mutations within a gene. Read it @nature.com: buff.ly/dYn0NjS @UMassChan.bsky.social @eriksontheimer.bsky.social

Site-specific, multi-kilobase insertions and over-writes in mammalian cells, without DSBs, HDR, recombinases, integrases, transposases, or active cell cycling? Using fully or predominantly single-stranded DNA donors? 1/15

For the 2026 primary elections, NPR has collected deadlines and information on how to register to vote — online, in person or by mail — in every U.S. state and territory.

How to register to vote and check your registration status

For the 2026 primary elections, NPR has collected deadlines and information on how to register to vote — online, in person or by mail — in every U.S. state and territory.

n.pr

Registration for CRISPR 2026 is now open: web.cvent.com/event/ac20b6.... Early-bird price discounts are available until the end of February.

The CRISPR 2026 website is up! Links for abstract submission and registration will be available February 1st: web.cvent.com/event/ac20b6...

SCOTUS: considering race as one factor in a college applicant's file is blatantly unconstitutional ALSO SCOTUS: considering race as one factor in targeting whom to detain and deport is cool cool cool

Hot off the press from the RTI: Prime assembly with linear DNA donors enables large genomic insertions pubmed.ncbi.nlm.nih.gov/40667017/?ut... #RNA #RNATherapeutics

Prime assembly with linear DNA donors enables large genomic insertions - PubMed

Targeted insertion of large DNA fragments has promising applications for genome engineering and gene therapy^1,2. Twin prime editing (PE) guide RNAs (pegRNAs) have enabled relatively large insertions,...

pubmed.ncbi.nlm.nih.gov

Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription. www.cell.com/cell/fulltex... Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.

Kiwa is a membrane-embedded defense supercomplex activated at phage attachment sites

Zhang, Todeschini, and Wu et al. show that the bacterial defense system Kiwa senses phage attachment at the membrane and assembles a transmembrane complex that halts infection by blocking phage DNA re...

cell.com

Fun news: I'm starting my research group at @rti-umasschan.bsky.social as the inaugural Maraganore Fellow! Our lab will focus on the RNA sequence-structure-function relationship in the cellular environment. Visit our website to explore open positions: schaerfenlab.com #RNA #Hiring #PostbacJobs

On Thursday, Anastasia Khvorova, PhD, received the 2025 Else Kröner Fresenius Prize for Medical Research, a $2.7 million award, for her pioneering work in the field of RNA-based therapies. 📸: Else Kröner-Fresenius-Stiftung #EKFprize25 #EKFS #RNA @ekfstiftung.bsky.social @rti-umasschan.bsky.social

"The consolidation/RIF plan pulls power away from scientists and puts it in the hands of political employees. It sets up Trump and Musk to kill NIH as an evidence-based science funder. We must stop this plan." New contributed post on our blog: Please read. It describes Orban and authoritarianism. 🧪

The NIH firing plan is really a radical institute merger and an authoritarian takeover

this is an Orbanization of US science: a move to exert political control over discovery, which will kill the US medical research industry and end cancer cures. The plan must be stopped. We can act.

open.substack.com

Pressing question of the day: when will @epigenetichulk start smashing puny genomes on Bluesky?