Really excited to finally show off our work on the specification of neuroblasts. While it has been a long-standing model for lateral inhibition, we show that Notch does not select the NB, but instead reinforces fate decisions. www.cell.com/current-biol... @currentbiology.bsky.social

Positional cues, not Notch, direct neuroblast selection during early neurogenesis in the Drosophila embryo

Using quantitative live imaging, Green et al. show that proneural gene expression is biased by positional cues and that Notch is activated only after neuroblast selection in the Drosophila embryo. Thi...

cell.com

Very cool new paper from the Tepass lab. they use optigenetics to enhance clustering of E-cadherin in vivo during embryo morphogenesis. This slows cell intercalation and axis extension, slows neural stem cell invagination but does not slow mesoderm invagination by apical constriction. WOW! 🧪

Girish Kale@girishkalephd.bsky.social · 2mo ago

Definitely check out the Preprint by Lerchbaumer et al. Lerchbaumer, G., Simoes, S., Etemadi, E., Zidan, F., Erdemci-Tandogan, G. and Tepass, U. (2026). E-cadherin clustering as a regulator of morphogenesis. bioRxiv. doi.org/10.64898/202...

Thank you for this very nice perspective on our preprint @girishkalephd.bsky.social !

Girish Kale@girishkalephd.bsky.social · 2mo ago

Had a lot of fun revisiting my old love for E-cadherin, writing this In Preprints article. Thanks Daniel @yosoyden.bsky.social for commissioning the article :) Also also, this is my second such article so far! (more yey's for me)

Definitely check out the Preprint by Lerchbaumer et al. Lerchbaumer, G., Simoes, S., Etemadi, E., Zidan, F., Erdemci-Tandogan, G. and Tepass, U. (2026). E-cadherin clustering as a regulator of morphogenesis. bioRxiv. doi.org/10.64898/202...

E-cadherin clustering as a regulator of morphogenesis

Cell adhesion enables animal multicellular development. E-cadherin and the cadherin-catenin adhesion complex at adherens junctions are engaged in dynamic interactions with actomyosin generated contrac...

doi.org

Our International Developmental Mechanics Zoom Seminar Series returns this fall! Interested in sharing your research with an international community? Sign up to speak at an upcoming session: sites.google.com/view/devmech... #DevBio #Mechanobiology #Morphogenesis

Nominations are open for 3 Biophysical Society of Canada awards: 🏅 BSC Fellow 🔬 Early Career Investigator Award 🤝 Michèle Auger Service Award The nomination deadline for all three awards is August 1 Award details and nomination requirements: biophysicalsociety.ca/awards/

Dear Dev Mech Enthusiasts! The Developmental Mechanics Seminar Series returns on 24 September. We have an exciting lineup of speakers. If interested in presenting your work/ attending it. Register here:https://tinyurl.com/2munv5bv @goncaerdemci.bsky.social @tarafinegan.bsky.social

International Developmental Mechanics Seminar Series

Please fill out the following survey if you are interested in the 2025-2026 International Zoom Seminars on Developmental Mechanics. Our website: https://sites.google.com/view/devmechseminars

tinyurl.com

And check out our tree!!! Such an awesome initiative ... thanks @dev-journal.bsky.social and @biologists.bsky.social !! forest.biologists.com/landscape/?i...

To learn more about the people behind the paper, we talked to the first author, Veronica Castle, and the co-corresponding authors @rodrigofg.bsky.social, Professor at the @utoronto.ca, and @goncaerdemci.bsky.social, Assistant Professor, University of Western Ontario, Canada: doi.org/10.1242/dev....

Read the Research Article ‘Cell divisions both challenge and refine tissue boundaries in the Drosophila embryo’ here: doi.org/10.1242/dev....

Cell divisions test and shape boundaries in Drosophila embryos This Research Highlight showcases work from Veronica Castle, @rodrigofg.bsky.social and @goncaerdemci.bsky.social: journals.biologists.com/dev/article/...

And if you are interested in the back story ...

The people behind the papers – Veronica Castle, Rodrigo Fernandez-Gonzalez and Gonca Erdemci-Tandogan

Boundaries between tissues are important for establishing correct patterning during development and must be able to resist forces generated in the tissue from processes such as cell division. In a new...

journals.biologists.com

Also so excited for this highlight from @dev-journal.bsky.social!

Rodrigo Fernandez-Gonzalez@rodrigofg.bsky.social · 7mo ago

Read the really nice highlight that @dev-journal.bsky.social wrote summarizing our study:

Really fun study led by Veronica Castle and @goncaerdemci.bsky.social, with key contributions by @merdekam.bsky.social and Rafael Perez-Vicente. With generous funding from #NSERC, #CIHR and @trogersresearch.bsky.social. @uoftcellsysbiol.bsky.social @bme-uoft.bsky.social @utoronto.ca @westernu.ca.

So excited our paper is out now!! It was a very fun project where we combined vertex models and in vivo experiments, and we showed cell divisions play a dual role for the Drosophila ME boundary by increasing tissue fluidity!

Rodrigo Fernandez-Gonzalez@rodrigofg.bsky.social · 7mo ago

Check out our new publication @dev-journal.bsky.social! If you thought that cell divisions challenge tissue boundaries ... you got half of the story! Using in vivo quantitative microscopy and math. modelling we show that divisions fluidize tissues and facilitate boundary refinement. 🧪 #drosophila

Tons of sadness in the news, but we should still celebrate important things. Happy International Day of Women and Girls in Science!!! @negberry.bsky.social, @willowp.bsky.social, @qeenyra.bsky.social, @anamcarmo.bsky.social, @krothphd.bsky.social, @goncaerdemci.bsky.social, @utoronto.ca

International Day of Women and Girls in Science

11 February

unesco.org

🚨 The International Developmental Mechanics Zoom Seminar Series is back on Sept 25! 🎤 We have an exciting line-up of speakers this fall. See the image below for details 🌐 Website: sites.google.com/view/devmech... 📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv

Congratulations to all the trainee award winners at #BSC2025! 🎉 Especially proud of our stellar undergrad Merdeka Miles for receiving a poster award - so well deserved!

Biophysical Society of Canada@biophyscanada.bsky.social · last yr.

Congratulations to all the trainee award winners at the BSC 2025!

It was such a pleasure to present at #CDBC2025! Truly appreciate the opportunity!

Andrew Simmonds 🇨🇦@simmondlab.bsky.social · last yr.

One thing I enjoy about the Canadian Developmental Biology Conference is diversity! - here is Gonca Erdemci-Tandogan, Dept Physics and Astronomy, Western University showing how “Cell divisions challenge tissue boundaries and sharpen them through tissue fluidity” #CDBC2025 @socdevbio.bsky.social

I'm excited to join @pritiagarwal.bsky.social and @tarafinegan.bsky.social as a co-organizer for the International Developmental Mechanics Seminar Series. The series will resume in September 2025, and call for speakers is now open! More info is on our new website: sites.google.com/view/devmech...

Celebrate #BiophysicsWeek w/ 3 trainee-organized virtual events to connect, learn, and have fun: 🧠Trivia Night – Mar 24, 6PM ET 🎤Career + Research talk @isaacli.bsky.social – Mar 27, 1:30PM ET 🥖Biophysical Gastronomy – Mar 29, 2PM ET 📍Register here: events.teams.microsoft.com/event/dd0a33...

📢Deadlines for the BSC 2025 Annual Meeting in Hamilton are coming up! April 1: Early registration & abstract submission deadline April 15: Trainee travel award application deadline Please visit biophysicalsociety.ca for more details.