Magda Kopczyńska
@mgkopczynska.bsky.social
PhD canditate in @stoplab.bsky.social team intertwined with chromatin & transcription termination 🌀
Studying gene ends is becoming even more fascinating! Curious why? Read our News & Views "Transcriptional readthrough progresses from incidental byproduct to therapeutic opportunity" inspired by the recent publication by Podszywałow-Bartnicka and @karlaneugebauer.bsky.social @natsmb.nature.com
Our paper (@stoplab.bsky.social), in collaboration with the Nojima lab (@pol2rna.bsky.social @chiheron.bsky.social), on the role of chromatin modifier SETD2 at both ends of the transcriptional cycle, is now published in @emboreports.org 🪅 (1/5) link.springer.com/article/10.1...
Interested in antisense oligonucleotides? Check our story about downstream-of-gene ASOs (DG-ASOs)! Together with the Roche Innovation Center we identified transcription termination windows of protein-coding genes as ASO target regions. link to BioRxiv: www.biorxiv.org/content/10.6...
Very excited about this one - it is definitely worth remembering that 3' end processing and transcription termination are distinct processes and play crucial roles in gene expression 🧬
Agata Stepien@agatakstepien.bsky.social · 8mo agoDid you know that changes in pre-mRNA 3' cleavage and RNAPII termination can go in different directions? Even more, the spacing between these two events is linked to the gene expression level❗️Check out our latest pre-print to learn more tiny.cc/330w001 1/6
HIRING! STOP lab is looking for a Research Assistant (Technician) with experience in protein expression and purification. Job & project description and how to apply here: euraxess.ec.europa.eu/jobs/367610
🚨 New preprint from our labs (STOP lab @stoplab.bsky.social & Nojima lab @pol2rna.bsky.social @pyrolyn.bsky.social)! We've been digging into how chromatin remodeler SETD2 controls the start and end of transcription 👇 www.biorxiv.org/cgi/content/... (1/5)
Honored to receive an award from @polskaakademianauk.bsky.social in Poznań for the best 2024 publication led by a PhD student. Our study published in @narjournal.bsky.social highlights a key marker defining gene ends — helping improve genome annotations. Read more 👉 academic.oup.com/nar/article/...
"I have been prepared for evil, for greed, for cruelty, for injustice – but I did not anticipate that the people in power would also be such huge losers." 🤷🏻♀️ www.theguardian.com/commentisfre...
I knew one day I’d have to watch powerful men burn the world down – I just didn’t expect them to be such losers | Rebecca Shaw
Elon Musk and Mark Zuckerberg’s desperation to be cool as they suck up to Donald Trump is so cringe it makes my skin crawl
theguardian.com
Do you know where transcription of a gene actually stops? Hint: it is not the annotated gene end. In our new paper in Nucleic Acids Research we argue that phosphorylation on threonine 4 of RNA Pol II CTD is a marker of transcription termination in animals... 🧵 academic.oup.com/nar/advance-...
Great news & strategic decision @donald-tusk.bsky.social @andrzej-domanski.bsky.social: 500 mln top-up for🇵🇱research @ncngovpl.bsky.social in 2025! Strength. basic research is the best way to drive INNOVATION and INVEST in the FUTURE of 🇵🇱&🇪🇺 A frontline country can do it - what's your gov's excuse?
Narodowe Centrum Nauki@ncn.gov.pl · 2y agoPremier @donald-tusk.bsky.social zapowiedział, że #NCN otrzyma 500 mln złotych w obligacjach! @kancelariapremiera.bsky.social @andrzej-domanski.bsky.social @ministerstwonauki.bsky.social ncn.gov.pl/aktualnosci/...
