Can we override our programming? www.wiringthebrain.com/2026/10/can-... New blogpost (after a long hiatus!) - inspired by #Lanterns and #EastofEden
Ana Dorrego Rivas
@adorrego.bsky.social
Postdoc @GrubbLab- Centre for Developmental Neurobiology - King's College London | Unconventional neurons, axons, dendrites, and how they talk to each other! | Wellcome Trust ECA Research fellow | bioRxiv affiliate | 🇪🇸🇫🇷🇬🇧 Barcelona ➡️ Bordeaux ➡️ London
Also, 100% guaranteed that if you see me posting microscopy pictures, it's because I am knee-deep in data analysis #FluorescenceFriday
Indecisive mitral cells or weeping willows? 🧠🌳🔬🧪
Why optogenetics deserves the hype www.wiringthebrain.com/2013/09/why-... (a piece I wrote in 2013 explaining how it works and why modulating specific cell types is so key to understanding how neural circuits and systems work)
Why optogenetics deserves the hype
Optogenetics has come in for some stick lately, with a number of people criticising the hype that this technique generates in some quar...
wiringthebrain.com
Exclusive: A new analysis refutes James Watson’s claim that he was the first to recognize the significance of the famed photograph 51. https://scim.ag/4rTKck8
How did Rosalind Franklin miss the helix in her iconic DNA image? She didn’t
New analysis refutes James Watson’s claim he was first to recognize significance of famed photograph 51
scim.ag
Huge congratulations to all three Nobel Laureates, and especially Peter Hegemann! 👏 His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨ Proof that groundbreaking discoveries don't always come from animal models! 🔬
BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Too many neuro preprints to keep track of, so I made a monthly ranking of the most-read ones on bioRxiv. Not a measure of quality, just what people are reading. Here's the fresh ranking for September: robertodf.github.io/biorxiv-top/
This. Sign up, support and turn out now, as a glimmer appears for the road to #RejoinEU
I remember in 2015/2016 how SLOW pro-EU mobilisation was -it only really exploded AFTER the Brexit vote. Let's not make that mistake again. At European movement UK, we've been building the mobilisation structures needed. All you need to do is join us. --> www.europeanmovement.co.uk/signup-newsl...
Last year, Janos Fuzik and I organized a symposium on voltage imaging for the @fens.org regional meeting in Oslo. We then teamed up with our speakers to write a review on this. I am very happy to share that this review is now out in #EJN! #neuroscience 🧠 onlinelibrary.wiley.com/share/author...
Advances and Applications in Population Voltage Imaging
Reader environment loaded
onlinelibrary.wiley.com
"Comment une odeur devient-elle une madeleine de Proust ?" sur @france.theconversation.com
Comment une odeur devient-elle une madeleine de Proust ?
L’origine de l’effet « madeleine de Proust » ne peut pas être expliquée exclusivement par des arguments d’anatomie du système nerveux et du cerveau.
theconversation.com
Taking scientific production as an end-in-itself is disastrous in an env where AI can amplify prod. beyond all capacity for social cognitive digestion. If the end of science isn't the improvement of all individual human experience & if the enriching of cognition isn't part of that, what use is it?
As AI increases both productivity & ease of creating slop, there's a big challenge for those of us disseminating science. This from @pracheeac.bsky.social is an essential read. [disclaimer: she & I've spent 10+ years a̶r̶g̶u̶i̶n̶g̶ ̶a̶b̶o̶u̶t̶ discussing this stuff] 1/n pracheeac.substack.com/p/arxiv-is-k...
I was in Paris yesterday talking about mitral cell development to a very enthusiastic crew as part of the NeuroDev Paris seminars 🧠🇫🇷🧪 The most beautiful cells with the weirdest phenotypes.
Great reporting from @robinbisson.bsky.social on an absolutely dire funding situation…
MRC success rates drop sharply after grants overhaul. Warnings of “catastrophic” impact on medical researchers as some rates fall below 5 per cent. www.researchprofessionalnews.com/rr-news-uk-r...
I realise this is a long shot, but do I know anyone in Europe working with inducible mouse models of Parkinson (e.g. 6OHDA lesions)? Who, crucially, is willing to host and train a PhD student, sometime next year? 🧠 #neuroscience
I just published: How do we recognize world-class science? Not by the journal it appeared in What I told early-career researchers about prediction, rigour, failure, priors — and the tyranny of bar graphs. kamounlab.medium.com/how-do-we-re...
How do we recognize world-class science? Not by the journal it appeared in
What I told early-career researchers about prediction, rigour, failure, priors — and the tyranny of bar graphs.
kamounlab.medium.com
Good fucking God, don't give any of these things unpublished data. Its data security 101.
Four days ago, a scientist was surprised by the news that Anthropic discovered new virus genes for making DNA. He says he’s been studying them for years—and feeding his data to Anthropic’s AI as part of his own research. Coincidence? Here’s my story. nyti.ms/3VSWayc
Four days ago, a scientist was surprised by the news that Anthropic discovered new virus genes for making DNA. He says he’s been studying them for years—and feeding his data to Anthropic’s AI as part of his own research. Coincidence? Here’s my story. nyti.ms/3VSWayc
Did Anthropic’s A.I. Really Make a Scientific Discovery on Its Own? (Gift Article)
An expert at the University of Copenhagen said his team had been sharing its research with the company’s A.I. model, Claude, and that its new finding matched their work.
nyti.ms
Science may humble me daily but Wordle will absolutely not. Wordle 1,926 3/6 🟨🟩⬜⬜⬜ 🟩🟩🟩🟨⬜ 🟩🟩🟩🟩🟩
New lab preprint: @grace-padilla.bsky.social studied how zebrafish respond to chemical cues of death and decay. Brief exposure initiated a persistent state, but not through olfaction. Instead, these cues' basic pH was detected by trigeminal neurons and TrpA1 channels www.biorxiv.org/content/10.6...
Decay chemicals activate a pH-sensing pathway to initiate a persistent state
Animals use multiple sensory systems to identify signs of danger, including dead conspecifics. Fish can identify decaying conspecifics from chemosensory cues, which prompt a long-lasting avoidance; th...
biorxiv.org
My least effort feminist action of recent years has been to completely train myself out of the common Irish and British habit of using the word c**t to refer to men who are quite plainly horrible cocks. Follow me for more woke ideology.
Interesting to see (possible) ER tubules running through these dendritic constrictions. Might also influence computation.
Dendritic shaft constrictions shape synaptic integration in neurons www.science.org/doi/10.1126/...
LMAO gotta love peer review: ”But outside experts said that the Anthropic researchers have yet to do the research required to confirm that they’ve found something new.” 🧪 www.nytimes.com/2026/09/24/s...
Anthropic’s A.I. Is Teaching Itself Biology. Now It’s Made Its First Discovery. (Gift Article)
Scientists at the company announced their first finding: a group of enzymes whose function is unknown.
nytimes.com
Dendritic shaft constrictions shape synaptic integration in neurons www.science.org/doi/10.1126/...
Dendritic shaft constrictions shape synaptic integration in neurons
For nearly 150 years, textbooks have described dendritic morphology as optimized for efficient synaptic voltage transfer from spines to the soma, implemented as a tubular design respecting Rall’s 3/2 ...
science.org
2 tweeprints to go. Good morning! If you've moved already today, you probably asked yourself: how? How did I even get up? Not the hangover. How does your nervous system orchestrate your muscles so well? We've been asking ourselves, too: How can fixed networks produce so many firing patterns?
Playing Pong with spikes, dancing rate networks, composite engrams & #ihngrams4engrams. The labs most recent work-in-progress, now on biorxiv.com. Stay tuned for more Pong doi.org/10.64898/202... Dale doi.org/10.64898/202... Composite engrams doi.org/10.64898/202... Ihngrams doi.org/10.64898/202...
This is it. This is what everyone is enabling by humoring genAI: you spend months writing something that took you years to get at, for an opaque algorithm that a few control to spit a number and cut you off right there and then. This is what we're up against 🧪
Had a UKRI funded grant proposal rejected at the "AI triage stage". "This AI-based triage was used only to identify approximately 50% of the strongest proposals to take forward to full human review." 🧪 #academicsky
Too early to know implications of Anthropic and Claude's discovery on enzymes, says the CRG's Bernardo Rodriguez in @elmundoes.bsky.social. The researchers also says peer review remains fundamental to ensuring the study meets minimum quality standards. www.elmundo.es/salud/2026/0...
Anthropic anuncia que la IA ha descubierto un nuevo sistema de enzimas hasta ahora desconocido y similar al 'corta-pega' genético
La compañía estadounidense Anthropic ha anunciado que su modelo de inteligencia artificial Claude ha descubierto un nuevo sistema enzimático cuyas propiedades recuerdan a las de...
elmundo.es
Registration now open for our AIS meeting, organised with @royalsociety.org in Edinburgh, 7th-8th December 2026! royalsociety.org/science-even...