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@cedric-blanpain.bsky.social

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@cedric-blanpain.bsky.social · 10mo ago

So happy to see that Nature Cancer had chosen our picture as the cover of their September issue together with the publication of our paper on stem cell plasticity during prostate tumor initiation. Congratulations to @ChenJiang919 and @yura__song

Nature Cancer@natcancer.nature.com · 10mo ago

🍂Our September issue is OUT NOW! Featuring, among others: - A Perspective on #drugconjugates - #immunotherapy studies - research on GBM invasion - method for #singlecell analyses of #CTCs 🔗 www.nature.com/natcancer/vo...

@cedric-blanpain.bsky.social · last yr.

I am delighted to share our new study uncovering the role of innate immunity in regulating cell plasticity and reprograming of prostate tumor initiating cells published in @NatureCancer . Congrats @ChenJiang919 and @yura__song , the first authors, www.nature.com/articles/s43...

Innate immunity and the NF-κB pathway control prostate stem cell plasticity, reprogramming and tumor initiation - Nature Cancer

Blanpain and colleagues delineate lineage reprogramming following PTEN deletion in different prostate cancer-originating cells, demonstrating that in basal cells the NF-κB pathway and innate immunity ...

nature.com

Lars Velten@larsplus.bsky.social · last yr.

Out @nature.com: Clonal tracing with somatic epimutations 🧬 Single cell methylome encodes cell state & clonal identity 🔨 EPI-Clone reads out both (+mutations, +RNA) at scale 🩸 Clonal expansions of HSCs are universal from age 50, not driven by CH mutations doi.org/10.1038/s415... 🧵

Clonal tracing with somatic epimutations reveals dynamics of blood ageing - Nature

The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing th...

doi.org