As promised, we run the town and gown 10k! In the photos are group members @rogerrubiosanchez.bsky.social Juliette Bucci, Brian Ng, Cathrine Fan, Sebastian Krauss and Lorenzo (the old one). Thanks to all who supported us with donations to @mdukcharity.bsky.social

Hey! Some group members and I are running a 10k race in Cambridge this Sunday, and raining some funds for @mdukcharity.bsky.social Please donate and share! @ceb.cam.ac.uk @pembroke1347.bsky.social sportsgiving.co.uk/sponsorship/...

SportsGiving - Entry: Lorenzo Di Michele

Lorenzo Di Michele is fundraising for charity. Visit their fundraising page to sponsor them online now!

sportsgiving.co.uk

Check out this new @jacs.acspublications.org paper by @rogerrubiosanchez.bsky.social. Building cation responsive DNA receptors for synthetic cells!

Roger Rubio Sánchez@rogerrubiosanchez.bsky.social · 11mo ago

Really happy to see this published in its final form @jacs.acspublications.org! 🧬 In this paper, we introduce a new class of biomimetic receptors to host functionality in synthetic cell membranes Elita Peters @dianatanase.bsky.social @dimichelelab1.bsky.social pubs.acs.org/doi/10.1021/...

Happy to have developed the theory here, linking sequence-dependent charge patterns to favourable electrostatic interactions between homologous dsDNA🧬🧬 Matching theory & expt suggests a physical basis for sequence recognition that may underpin aspects of recombination, DNA repair, and replication.

Di Michele Lab@dimichelelab1.bsky.social · 11mo ago

It turns out sDNA 🧬 interacts selectively! Andy Stannard measured these interactions very (very) precisely, and Ehud Haimov, @drjonhedley.bsky.social‬, Alexei Kornyshev worked out how it all works. It has to do with charge correlation... Check it out here chemrxiv.org/engage/chemr...

Also - we still need to decide where to submit this. Let’s try an unofficial poll. Where do BlueSky DNA enthusiasts see manuscript?

Di Michele Lab@dimichelelab1.bsky.social · 11mo ago

It turns out sDNA 🧬 interacts selectively! Andy Stannard measured these interactions very (very) precisely, and Ehud Haimov, @drjonhedley.bsky.social‬, Alexei Kornyshev worked out how it all works. It has to do with charge correlation... Check it out here chemrxiv.org/engage/chemr...

It turns out sDNA 🧬 interacts selectively! Andy Stannard measured these interactions very (very) precisely, and Ehud Haimov, @drjonhedley.bsky.social‬, Alexei Kornyshev worked out how it all works. It has to do with charge correlation... Check it out here chemrxiv.org/engage/chemr...

Detection and quantification of counterion-mediated homologous recognition in double-stranded DNA

Stretches of double-stranded DNA sharing the same sequence can recognise each other in cells. This phenomenon, known as homologous recognition, is essential for DNA recombination and repair. Yet, its ...

chemrxiv.org

My work on DNA condensates @dimichelelab1.bsky.social is now out! 🧬🎉🍬 A huge thank you to @francolab.bsky.social lab for their invaluable expertise and to everyone in our lab for their insights, feedback, and countless discussions along the way. I’ve learned so much from working with you all!

Di Michele Lab@dimichelelab1.bsky.social · 12mo ago

Thrilled to share this new Adv. Sci. paper by @dianatanase.bsky.social with Dino Osmanovic @rogerrubiosanchez.bsky.social @laylamalouf.bsky.social @francolab.bsky.social. We demonstrate a modular approach to program internal phase separation in DNA condensates 1/n doi.org/10.1002/advs...

Thrilled to share this new Adv. Sci. paper by @dianatanase.bsky.social with Dino Osmanovic @rogerrubiosanchez.bsky.social @laylamalouf.bsky.social @francolab.bsky.social. We demonstrate a modular approach to program internal phase separation in DNA condensates 1/n doi.org/10.1002/advs...

Internal Phase Separation in Synthetic DNA Condensates

The modular, programmable system of DNA nanostructures developed provides programmatic control over multiphase condensate behavior, enabling mapping onto a predictive Flory-Huggins model. This combin...

doi.org

Thrilled to share our latest preprint on expressing synthetic organelles made from RNA nanostructures in bacteria! 1/n www.biorxiv.org/content/10.1...

Expression of nano-engineered RNA organelles in bacteria

Designing synthetic biomolecular condensates, or membrane-less organelles, offers insights on the functions of their natural counterparts, and is equally valuable for cellular and metabolic engineerin...

biorxiv.org

Origami Black Hole xkcd.com/3033

Happy new year everyone, and some great news! We have an opening for a PhD candidate to join our lab @cebcambridge.bsky.social in October 2025 as part of the new exciting MSCA Doctoral Network @comeincell.bsky.social jobs.cam.ac.uk/job/49240/

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Department of Chemical Engineering and Biotechnology, Cambridge@ceb.cam.ac.uk · 2y ago

News alert! Prof. Ljiljana Fruk and a team of researchers have developed a urine test that could detect early signs of lung cancer. Backed by Cancer Research UK, it’s a step forward in accessible healthcare. Read the full story: www.ceb.cam.ac.uk/news/urine-t... #DrivenbyCuriosity #DrivingChange

Great to see @pembroke1347.bsky.social here!

HI! 👋 We’re the Department of Chemical Engineering and Biotechnology at the University of Cambridge. We like: 🧪Science that pushes the envelope 🌏Working to solve the world’s biggest challenges 🧑‍🔬Collaborating with amazing scientists 🫖Tea! 🤖Robots! #DrivenByCuriosity #DrivingChange

Amazing to see our work on designer RNA condensates featured on the cover of @naturenano.bsky.social!!! #RNAnanotech #condensates #SynCells www.nature.com/articles/s41...

Co-transcriptional production of programmable RNA condensates and synthetic organelles - Nature Nanotechnology

Controlling RNA and protein condensation is helpful in synthetic biology. Here the authors show programmable assembly of synthetic RNA nanostructures into designer membrane-less organelles that select...

nature.com