Great news to share for #MicroscopyMonday! Huge thanks to everyone in the @ebrahim-lab.bsky.social crew and collaborators - feels amazing to have my first journal cover image on JCI Insight! 🔬

Ebrahim Lab@ebrahim-lab.bsky.social · 10mo ago

Very excited to share the latest work from our lab in @insight.jci.org, highlighting a role for the #septin #cytoskeleton in protecting against "leaky gut", by recruiting non-muscle myosin II and stabilizing the tight junction. Credit to @dominikrobak.bsky.social for the stunning cover image!

Happy #MicroscopyMonday! Bees didn’t invent the honeycomb—biology’s been doing it at the single-cell level all along. 🟢 GFP-tagged junctions 🔵 Hoechst-stained nuclei A living mouse intestinal villus. No blueprint. Just (bio)physics. #intravitalimaging #biophysics #OME #microscopyenvironment

#MicroscopyMonday | Colon-scoping turned coral reef Was imaging the colon when I accidentally stumbled into this glowing patch of vascularized white adipose tissue. 🔵 mT/mG mouse (mT-only) → red membranes shown in cyan Accidental imaging hits different. #IntravitalImaging #LiveImaging

#3DThursday | Intestinal villi in all their folded glory These self-renewing, nutrient-absorbing structures are beautiful and functional. 🔴 Phalloidin 🔵 DAPI 🟢 Clvd cas-3 (extrusion in action!) Fixed tissue 3D imaging = big insight, tiny resolution. #Microscopy #3DImaging #biophysics #intestine

Hey #BPS2025! Wanna look at cool pictures and see what happens in mice’s intestine throughout live imaging? Come by my poster at LB69 on Monday to learn more! Got some cool stuff to experience imaging data like never before! #Biophysics #Science #Microscopy #VR