Since I moved to @mrclmb.bsky.social I’ve been trying to answer this: Why are some mammals active at night and others in the day? Today our answer is out @science.org www.science.org/doi/10.1126/.... If you’re interested in circadian biology, evolution or how timing shapes physiology, take a look

A cellular basis for the mammalian nocturnal-diurnal switch

Early mammals were nocturnal while dinosaurs dominated the daytime. Mammalian transition to daytime activity accelerated after the Cretaceous-Paleogene extinction, but the underlying mechanisms remain...

science.org

A conference in Europe gives the opportunity to not travel by plane So, I'm travelling to GRC Chronobiology #circadian in Barcelona by train from Cambridge. Smooth ride so far but Eurostar is unexpectedly busy! Next connection - the overnight from Paris to Perpignan. Travelling backpacker style 😀

If anyone is interested, I've updated our take on a cellular basis of the mammalian nocturnal-diurnal switch @biorxivpreprint.bsky.social We've refined the paper (for the better, hopefully!) - my fave updates are the results from a collab with Zoonomia (Fig 3) www.biorxiv.org/content/10.1...

A cellular basis for the mammalian nocturnal-diurnal switch

Early mammals were nocturnal until the Cretaceous-Paleogene extinction enabled diurnal niche expansion. Diurnality evolved multiple times independently, but the mechanisms driving this shift remain un...

biorxiv.org

#EMBOClimateResilience “The way in which our universities have divided up the sciences does not reflect the ways in which nature has divided up its problems” @embo.org @monicabettencourt.bsky.social

I was today years old when I first heard this gorgeous quote at #EMBOclimateResilience: “The way in which our universities have divided up our sciences does not reflect the way in which nature has divided up its problems” (Kurt Salzinger) - thank you @luciastrader.bsky.social!

Is anyone (virtually) attending the @embo.org EMBO Workshop on Integrating cell and planetary scales to address climate resilience? Looks fascinating but I think I put my application in too late to get the stream link. So, if anyone wants to fill me in I would love to hear! #EMBOclimateresiliance

Biology-inspired design has always fascinated me. I am by no means an expert, but I was interested to see this paper in @naturecomms.bsky.social this month - using the autonomous Kai oscillator for time-dependent synthetic assembly: "circadian materials". www.nature.com/articles/s41... #1stpost

Programming scheduled self-assembly of circadian materials - Nature Communications

Harnessing biomolecular systems to endow synthetic materials with life-like properties is a significant challenge. Here, the authors use the biomolecular KaiABC circadian clock proteins to control aut...

nature.com