Register now for our welfare webinar exploring the role of anaesthesia and analgesia as key refinements for fish used in research. 📅 22 October, 12.30 – 13.30.  🙋🏻‍ For researchers, animal technicians and veterinarians 📜 Certificates of attendance available 👉 nc3rs.org.uk/events/welfa...

Would you like a little extra help designing in vivo experiments? Join me on 29 September as I demonstrate how to use the @nc3rs.bsky.social's Experimental Design Assistant (EDA). nc3rs.org.uk/events/exper...

Looking forward to joining the panel for the ‘Rigorous by design: Strengthening research that involves animals’ webinar from the @nationalacademies.org. Register to hear about improving the reliability of results by carefully planning and reporting your experiments. 👇

NC3Rs@nc3rs.bsky.social · 4w ago

At this @nationalacademies.org webinar @drejpearl.bsky.social will share NC3Rs experimental design and reporting resources to support rigorous and reproducible experiments, reducing the wastage of animals in poor quality studies. 📅 7 October, 18.00 (BST)/13.00 (ET) 👉 nc3rs.org.uk/events/rigor...

Join us at next week’s welfare webinar to hear about the latest evidence and practical advice on skin swabbing as a refined alternative to fin clipping for fish DNA sample collection. 📅 Thursday 24 September, 12.00 – 13.00 ⏰ Registration closes: Wednesday 23 September 👉 nc3rs.org.uk/events/welfa...

NC3Rs@nc3rs.bsky.social · 2mo ago

Register now for our upcoming welfare webinar on fish skin swabbing for refined DNA sampling. 📅 24 September, 12.00 – 13.00 🧑‍🔬 For researchers, animal technicians and veterinarians 📜 Certificates of attendance available 👉 nc3rs.org.uk/events/welfa...

I attended my first @royalstatsoc.bsky.social conference last week. An amazing conference! Everyone was so welcoming. Many talks mentioned the need for well designed experiments and emphasised that statisticians should get talking to researchers early on and plan projects together. 100% agree.

Do you work with Xenopus? Want to know the latest best practices in housing and husbandry? Want tips for implementing reduction and refinement? Check out the new Xenopus protocols book 👇

NC3Rs@nc3rs.bsky.social · last mo.

In the latest edition of 'Xenopus protocols' Esther Pearl (NC3Rs Experimental Design Programme Manager) has contributed to two chapters alongside experts from the European Xenopus Resource Centre, covering key refinements alongside breeding and colony management to reduce the number of frogs used.

I’ve ARRIVEd (!) at the 2026 @royalstatsoc.bsky.social conference. Looking forward to a great meeting! Are you at the conference and wondering what sessions to attend? Tomorrow, Penny Reynolds, William Browne and I are talking about biomedical research study design. Join us!

I am excited to be attending my first ever @royalstatsoc.bsky.social conference this year! Drs Penny Reynolds, William Browne and I will be presenting 'Biomedical research study design: Back to basics in the age of AI'. 🗓️ Tuesday 8 Sept 15.40 - 17.00 I hope to see you there!

NC3Rs@nc3rs.bsky.social · last mo.

Our session at next week’s Royal Statistical Society conference will highlight the important role of statisticians alongside NC3Rs resources to ensure rigour in biomedical research and reduce animals wasted in experiments that produce unreliable results. Find out more: nc3rs.org.uk/events/royal...

Register now for our upcoming welfare webinar on fish skin swabbing for refined DNA sampling. 📅 24 September, 12.00 – 13.00 🧑‍🔬 For researchers, animal technicians and veterinarians 📜 Certificates of attendance available 👉 nc3rs.org.uk/events/welfa...

In our latest blog Fiona Sewell, NC3Rs Head of Toxicology, discusses collaborating with the global community on one of the most challenging questions in regulatory science – how to balance assuring human reproductive health with avoiding unnecessary animal suffering: nc3rs.org.uk/news/finding...

📄Transparently and comprehensively reporting animal research is important for both research quality and the 3Rs. ✍️Penny Reynolds and I have recently written an article looking at the progress we have made in reporting research involving animals, what we still need to tackle and future directions. 👇

NC3Rs@nc3rs.bsky.social · 2mo ago

Biostatistician Penny Reynolds and NC3Rs Programme Manager @drejpearl.bsky.social discuss transparent reporting of animal research in the 60th anniversary edition of the Laboratory Animals Journal, exploring the link between the 3Rs, scientific quality and animal welfare: doi.org/10.1177/0023...

Do you serve on, support, or advise an Animal Research Governance Committee (e.g., AWERB, IACUC, or Animal Welfare Committee) that reviews in vivo research applications? Would you like support to help you check if research protocols are sex-inclusive?

NC3Rs@nc3rs.bsky.social · 3mo ago

Three months on from launching SIRF-UP, an @eu-sabv.bsky.social initiative to support ethical review bodies assess sex inclusivity in animal research, a new publication renews our call to get involved, share your experiences and use the Sex Inclusive Research Framework. 👉 doi.org/10.1177/0023...

The fifth annual Galleria mellonella workshop returns with a two-day programme including a research seminar and hands-on laboratory sessions. Organised by @gmrc.bsky.social to support the use of Galleria as a partial replacement model. 📅 8 – 9 September 📍 Exeter, UK 👉 nc3rs.org.uk/events/galle...

2026 Xenopus Researcher Survey - OPEN NOW - forms.gle/uDUkGCrhpXCc... Your feedback is highly valuable. Help us make Xenbase more helpful to your research! #science #devbio #cellbio #xenopus #frogs

3Rs leaflets are available to engage public audiences about efforts to replace, reduce and refine animal use in research: nc3rs.org.uk/3rs-resource... Created by Dr Yu Liu @mrc-lms.bsky.social with the support of the NC3Rs Communications Team and funding through our public engagement award scheme.

Please repost !! SANTA CRUZ DEVELOPMENTAL BIOLOGY CONFERENCE 2026. Deadline to register your abstracts for the meeting is Monday June 1. Please get those abstracts in ! scdb2026.sites.ucsc.edu

Very pleased to hear that Nature is expanding Registered Reports to all fields they publish. Registered reports put the focus on the research question and the quality of methods AND peer review helps you improve the methodology before you get started! What's not to like?? www.cos.io/initiatives/...

Registered Reports

Peer review before results are known to align scientific values and practices.

cos.io

Daniel Lakens@lakens.bsky.social · 5mo ago

Excellent news! Nature is expanding Registered Reports to all the fields in which they publish! A great result by all those proposing this strong solution to publication bias and selective reporting (and getting expert feedback before data collection)! www.nature.com/articles/d41...

Want help making teaching experimental design more interactive? Join us in June for the NC3Rs/iRISE Train-the-Trainer workshop: Reproducibility & the Experimental Design Assistant (EDA)! 👇

iRISE@irise-eu.bsky.social · 5mo ago

1/8 iRISE Train-the-Trainer workshop: Reproducibility & the Experimental Design Assistant (EDA)

Looking for a way to make teaching experimental design more interactive? Join me, Gillian Currie and Sarah Morgan for the online Reproducibility and the Experimental Design Assistant Train-the-Trainers course 👇

NC3Rs@nc3rs.bsky.social · 5mo ago

Our Experimental Design Assistant (EDA) can be used as a tool to teach others about key experimental design concepts in an interactive way. Join our online train-the-trainers workshop with @irise-eu.bsky.social to find out more. 📅 10 and 17 June, 13.00 – 16.00 BST 👉 nc3rs.org.uk/events/irise...

Earlier this year I ran an EDA train-the-trainers course for a group of enthusiastic trainers from CAMARADES Turkiye. They have gone on to train a further 178 researchers from 57 different institutions 🎉. This week? I am training a group from Argentina!

The countdown is on! The deadline for applications to our international 3Rs Prize, sponsored by GSK, is fast approaching. Submit your publication for consideration by Monday 4 May 2026: nc3rs.org.uk/internationa...

NC3Rs@nc3rs.bsky.social · 6mo ago

We invite researchers from around the world to showcase their 3Rs achievements on the global stage by applying for our annual NC3Rs 3Rs Prize: nc3rs.org.uk/internationa...

We are thrilled to be returning to @pintofscience.uk for our twelfth year as festival sponsors! Join us in Newcastle, Bristol and London as NC3Rs-funded scientists showcase innovations in replacement approaches and explore the future of alternatives to animals. 🎟️ pintofscience.co.uk/sponsor/nc3rs/

Do you serve on, support, or advise an Animal Research Governance Committee (e.g., AWERB, IACUC, or Animal Welfare Committee) that reviews in vivo research applications? Would you like support to help you check if research protocols are sex-inclusive? Get involved in SIRF-UP 👇

NC3Rs@nc3rs.bsky.social · 6mo ago

If you are involved in an ethical review body anywhere in the world (including AWERBs, IACUCs or Animal Welfare Committees), you can get involved in SIRF-UP. Answer a short survey, receive a support pack to apply the Sex Inclusive Research Framework and share your feedback: sabv.eu/article/sirf...

NC3Rs@nc3rs.bsky.social · 7mo ago

Register for upcoming 3Rs events from the NC3Rs and others taking place online this week: nc3rs.org.uk/events ⬇️ Details in the thread below.

Join me next month to learn how to improve the rigour of your experiments with the EDA! 📅 Wednesday 4 March, 16.00 – 18.00 (GMT) Register here 👇

NC3Rs@nc3rs.bsky.social · 8mo ago

Register for our next virtual workshop on using the Experimental Design Assistant (EDA): nc3rs.org.uk/events/exper... 📅 Wednesday 4 March, 16.00 – 18.00 (GMT) ⏰ Registration closes: Tuesday 3 March 📜 Certificates of attendance available for one CPD point

Want a bit of extra help designing your next in vivo experiment? Join me on 4 March for a demonstration of the @nc3rs.bsky.social Experimental Design Assistant: nc3rs.org.uk/3rs-resource...

Join me next week at #LoveMethods26. I am running a workshop demonstrating the features of the online tool the Experimental Design Assistant including how it can help us clearly describe our experimental plans with collaborators, funders, ethical review bodies and in our publications. 👇

NC3Rs@nc3rs.bsky.social · 9mo ago

Register for our online workshop ‘Rigorous experiments and clear communication with the Experimental Design Assistant’ as part of Love Methods Week this January: nc3rs.org.uk/events/love-... 📅 20 January, 9.00 – 11.00 (GMT) ⏰ Registration closes 19 January 📜 Certificates of attendance available

Is your New Year’s Resolution to design more reliable experiments? Join me at my #LoveMethods26 Experimental Design Assistant workshop. You will have time to design your own experiment, with me on hand to answer questions and give you support. Register here: nc3rs.org.uk/events/love-...

NC3Rs@nc3rs.bsky.social · 9mo ago

Register for our online workshop ‘Rigorous experiments and clear communication with the Experimental Design Assistant’ as part of Love Methods Week this January: nc3rs.org.uk/events/love-... 📅 20 January, 9.00 – 11.00 (GMT) ⏰ Registration closes 19 January 📜 Certificates of attendance available

Have you registered for #LoveMethods26 yet? Join us from Jan 19-23, 2026 with 19 online workshops and seminars focused on improving method reproducibility and transparency. Check it out: excelscior.uc.pt/love-methods...