Simone Gherardi

@drghem.bsky.social

EM doc based in Italy. Here for FOAMed and EM&CC community "Zebras are not unicorns" #FOAMed #Meu #EMIMCC

Doesn't seem like the population in which many bicarb lover or anyone would think about giving it in cardiac arrest (after the first dose of pressor). Even if I understand why the authors decided to give it early here, the trial doesn't adress properly the issue of bicard during arrest #EMIMCC

JAMA@jama.com · 2mo ago

📊 Research Summary: Sodium bicarbonate did not improve sustained return of spontaneous circulation or survival in adults with in-hospital cardiac arrest, supporting guidelines against its routine use. #CCR26 @criticalcarereviews.com ja.ma/43stWv0

JAMA Research Summary on Sodium Bicarbonate for In-Hospital Cardiac Arrest. A visual shows icons of a patient with a heart, a syringe, and vials. A clinical trial on 913 adults (median 73) found no significant improvement in sustained spontaneous circulation (39% with bicarb vs 37% with placebo) or survival outcomes.

first: combination inhaled epo + nitric simultaneously (I know its expensive, put it on my tab) epi gtt for MAP > 85 to improve cardiovascular reserve if the clot flies off then: 50 mg tPA (very little data on IR for clot in transit)

PPS - Bottom line is that if your critically unwell patient needs a CT scan you should just get the scan - Contrast-induced nephropathy is a myth emcrit.org/ibcc/contrast/ - Contrast allergy now just requires a dose of antihistamine - Radiation risks are minimal (especially for older adults)

kermit the frog is wearing a black hoodie and kermit the frog is wearing a black hood .

ALT: kermit the frog is wearing a black hoodie and kermit the frog is wearing a black hood .

media.tenor.com

DBP and pulse pressure are somewhat redundant. I added pulse pressure but they will generally trend in opposite directions provided the MAP is held in a somewhat fixed position around 70mm I guess the evaluation of congestion is kinda assumed... also I wanted to de-emphasize the whole fluids thing

ICU Snapshots: Young patient with multiple medical problems presented to ED for evaluation of "weakness". Decompensated; had to be intubated & placed on pressors (norepinephrine) before being transferred to our ICU

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ICU Practice - Return to Basics: When you prepare for the "average" intubation (no cardiac arrest, no active emesis), how do you pre-oxygenate the patient? Oxygen mask/nasal cannula? Non-invasive ventilation?

It's entirely possible that bronchodilation is due to the anticholinergic and ketamine isn't doing anything. Regardless, I've used this combination (high dose ketamine + IV scheduled glycopyrrolate) and like the study shows it seems to work well. Pending further data this seems reasonable.🤷‍♂️