James Conway

@drjamesconway.bsky.social

Research Fellow studying alpha-synucleinopathies (Bartels Lab) @UKDRI @UCL. Formerly of Kramer lab. Views are my own

I’m speaking at the Alzheimer’s Research UK Conference 2026 about our new paper, “Intestinal macrophages modulate synucleinopathy along the gut–brain axis”. Can’t wait to connect, share research, and learn alongside researchers at every stage of their careers. #ARUKconf

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Could targeting the gut's immune system tackle the early stages of Parkinson's? 🧠 A new study from @soyonhonglab.bsky.social & Tim Bartels (UK DRI at UCL) has revealed how Parkinson’s spreads from the gut to the brain - with the help of immune cells. Read more 👉 www.ukdri.ac.uk/news-and-eve...

Targeting the gut's immune system could tackle early stages of Parkinson's

New research, led by Dr Soyon Hong and Dr Tim Bartels at the UK DRI at UCL, has revealed how Parkinson’s spreads from the gut to the brain, with the hel

ukdri.ac.uk

Our paper is finally out! We position intestinal muscularis macrophages as early initiators of α-synuclein pathology and dopaminergic neurodegeneration in Parkinson’s models. They also drive local CD4⁺ T cell expansion, which subsequently migrates from gut to brain www.nature.com/articles/s41...

Intestinal macrophages modulate synucleinopathy along the gut–brain axis - Nature

Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understa...

nature.com