Edvard I Moser
@edvardmoser.bsky.social
Scientific Co-Director and Professor at Kavli Institute for Systems Neuroscience, NTNU, Norway. Neural network computation, grid cells. Nobel Prize Physiology-Medicine 2014.
Come and visit!
Jo Carpenter@jocarpenter.bsky.social · 4w agoThe Moser Group is presenting our work on Wednesday afternoon at #FENS2026! •Mechanism for L-R sweeps •Attention modulation of sweeps •Grid/place remapping rules & dynamics •”Mega torus” as a hi-capacity memory space •Moving the grid bump •Development of tori & rings •RSC/HC pops. in a spatial task
Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4 👇 www.biorxiv.org/content/10.6...
biorxiv.org
A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...
Place cells in CA1 lack topographical organization of firing locations | PNAS
Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...
pnas.org
I recommend this school to anyone interested in computation in the brain - it receives excellent reviews year after year, it is highly interactive and social, and the setting is remarkable.
Soledad Gonzalo Cogno@soledad-gcogno.bsky.social · 6mo agoApplications are now open for the summer school: 𝐌𝐚𝐭𝐡𝐞𝐦𝐚𝐭𝐢𝐜𝐚𝐥 𝐌𝐞𝐭𝐡𝐨𝐝𝐬 𝐢𝐧 𝐂𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐍𝐞𝐮𝐫𝐨𝐬𝐜𝐢𝐞𝐧𝐜𝐞 🧠 Apply before March 15: www.compneuronrsn.org 📍 Located in beautiful Eresfjord 🇳🇴 🗓️ Between July 6-24 Supported by the @kavlifoundation.org In collaboration with @kavlintnu.bsky.social
The hippocampal map has its own attentional control signal! Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See 📹 in post 4/6 and preprint here 👉 www.biorxiv.org/content/10.6... 🧵(1/6)
Attention-like regulation of theta sweeps in the brain's spatial navigation circuit
Spatial attention supports navigation by prioritizing information from selected locations. A candidate neural mechanism is provided by theta-paced sweeps in grid- and place-cell population activity, which sample nearby space in a left-right-alternating pattern coordinated by parasubicular direction signals. During exploration, this alternation promotes uniform spatial coverage, but whether sweeps can be flexibly tuned to locations of particular interest remains unclear. Using large-scale Neuropixels recordings in freely-behaving rats, we show that sweeps and direction signals are rapidly and dynamically modulated: they track moving targets during pursuit, precede orienting responses during immobility, and reverse during backward locomotion — without prior spatial learning. Similar modulation occurs during REM sleep. Canonical head-direction signals remain head-aligned. These findings identify sweeps as a flexible, attention-like mechanism for selectively sampling allocentric cognitive maps. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, Synergy Grant 951319 (EIM) The Research Council of Norway, Centre of Neural Computation 223262 (EIM, MBM), Centre for Algorithms in the Cortex 332640 (EIM, MBM), National Infrastructure grant (NORBRAIN, 295721 and 350201) The Kavli Foundation, https://ror.org/00kztt736 Ministry of Science and Education, Norway (EIM, MBM) Faculty of Medicine and Health Sciences; NTNU, Norway (AZV)
biorxiv.org
Gratulerer til Magnar Bjørås - en velfortjent og solid anerkjennelse av forskning i verdensklasse ved #NTNU!
Kavli Institute for Systems Neuroscience@kavlintnu.bsky.social · 7mo ago🎉 Gratulerer til vår kollega Magnar Bjørås, kåret til Årets trønder! Ved Kavli-instituttet er vi stolte over Magnars banebrytende forskning på sjeldne sykdommer som barnedemens - forskning som gir håp der det trengs aller mest. Les saken på NRK:
Board chair Bjarne Foss, @m-bmoser.bsky.social @edvardmoser.bsky.social @torgrande.bsky.social HM King Harald V, Secretary General of @nasjonalforeningen.no Bo Gleditsch, Centre Directors @asgeirkf.bsky.social Gøril Rolfseng Grøntvedt and Minister of Research Sigrun Aasland @kd.regjeringen.no
Come and join us tomorrow morning to discuss the latest findings from our lab(s)! We have many highlights to share!
Matteo Guardamagna@matteoguardamagna.bsky.social · 9mo agoStill at SfN on the last day? During the morning session on the 19th, 8:00AM - 12:00PM, come check out our posters from the Moser, Zong, and Gonzalo Cogno groups in row QQ ('Grid cells and spatially modulated cells'). Ephys, imaging, remapping, development, sweeps and more! 🧠 Detailed thread below 👇
1/8 How can the brain create countless unique memories using a single, universal metric of space? We’ve been waiting for the answer to this for two decades! Read it here: www.biorxiv.org/content/10.1...
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells
A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few systems where such ...
biorxiv.org
Edvard I Moser@edvardmoser.bsky.social · 10mo ago1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵 Preprint link 👇 www.biorxiv.org/content/10.1...
1/5 How does the brain turn the low-dimensional, universal grid cell metric into the rich, diverse codes needed for memory in hippocampal place cells? 🧵 Preprint link 👇 www.biorxiv.org/content/10.1...
Functional independence of entorhinal grid cell modules enables remapping in hippocampal place cells
A systems-level understanding of cortical computation requires insight into how neural codes are transformed across distinct brain circuits. In the mammalian cortex, one of the few systems where such ...
biorxiv.org
In case you still need a reason to attend the #BernsteinConference, let us remind you of this year's great speaker line-up 🤩 First up is Nobel laureate @edvardmoser.bsky.social! Be part of the bridge -- registration is open! 👉 bernstein-network.de/bernstein-co...
BonnBrain 2026 is a go! March 23–25, Bonn (DZNE, Bonn, Germany). Apply now: www.bonnbrain.de Limited slots. Presentations (posters/talks) selected from submitted abstracts. Keynotes & invited speakers 👇
Bonn Brain Conference
bonnbrain.de
BonnBrain Conference@bonnbrainconf.bsky.social · 11mo agoApplication is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!
So beautiful up there, only 58 min to the trailhead!
May-Britt Moser@m-bmoser.bsky.social · 12mo agoStorskarven 🤩
Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...
Event structure sculpts neural population dynamics in the lateral entorhinal cortex
Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...
science.org
Kudos to Minister Sigrun Aasland @kd.regjeringen.no for scrapping the language requirement for international PhD students and postdocs. I was interviewed by @nature.com about this decision that strengthens recruitment in a country where 75% of postdocs are from abroad. www.nature.com/articles/d41...
Norway set to scrap mandatory language training for foreign postdocs and PhD students
Researchers jubilant over swift ministerial response to rule they say would hamper international recruitment.
nature.com
There is hope! 💃🏻 www.khrono.no/statsrad-aas...
Statsråd Aasland ønsker seg mer synlige forskere
— Snakk mer om forskningen deres, om alt den brukes til og hvorfor den er så viktig, er et av budskapene fra forsknings- og høyere utdanningsminister Sigrun Aasland.
khrono.no
Edvard I Moser@edvardmoser.bsky.social · last yr.I was interviewed by @nature.com about the risk of talent exodus following Norway’s new language law. I hope the new government and science minister will change the internationalisation policy ASAP. @stortinget.no, @uhrno.bsky.social, @forskningspolitikk.bsky.social www.nature.com/articles/d41...
I was interviewed by @nature.com about the risk of talent exodus following Norway’s new language law. I hope the new government and science minister will change the internationalisation policy ASAP. @stortinget.no, @uhrno.bsky.social, @forskningspolitikk.bsky.social www.nature.com/articles/d41...
Scientists fight Norway’s language law, warning of talent exodus
Mandatory language courses for foreign researchers could harm Norway’s ability to attract the best talent, Nobel laureate says, as rule prompts legal challenge.
nature.com
This could be catastrophic. Consequences for US universities (and the world) may be beyond imagination.
Carl T. Bergstrom@carlbergstrom.com · last yr.1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...
Looking forward - opens so many doors!
Matteo Carandini@carandinilab.net · last yr.Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)
Grid cells have a geometry in time. Thanks to @azvollan.bsky.social l & @rjgardner.bsky.social for this heroic discovery. @ercresearch.bsky.social #KiloNeurons @m-bmoser.bsky.social @kavlintnu.bsky.social @nature.com @kavlifoundation.bsky.social www.nature.com/articles/s41...
Left–right-alternating theta sweeps in entorhinal–hippocampal maps of space - Nature
A study in rats proposes a mechanism for how the brain maps the surrounding environment, including places it has never seen, by alternating left and right forward sweeps in successive theta cycles.
nature.com
If you believe investment in science is needed to solve global challenges, join us in this call to action: www.febs.org/milan-declar... @m-bmoser.bsky.social @kavlintnu.bsky.social @kavlifoundation.bsky.social @ercresearch.bsky.social
Milan Declaration - FEBS
febs.org
Exciting opportunity to participate in development of the next generation of neurotechnology! I highly recommend @weijianzong.bsky.social and his lab!
Kavli Institute for Systems Neuroscience@kavlintnu.bsky.social · 2y agoWe are hiring two enthusiastic and highly motivated candidates for a PhD position or postdoctoral fellowship to work on model-driven systems neuroscience using MINI2P. Please apply here: www.jobbnorge.no/en/available...
Such a sad loss - of a great person and scientist.
May-Britt Moser@m-bmoser.bsky.social · 2y agoSo sad, what a lady, what a scientist💃🏻✨✨✨
Watch out for this guy; this is just the beginning. Many more breakthroughs to be expected! Congratulations, Weijian!
Kavli Institute for Systems Neuroscience@kavlintnu.bsky.social · 2y agoCongratulations to the brilliant Weijian Zong, who today received a FRIPRO grant by The Research Council of Norway for the miniature microscope #Mini2P, that allows researchers to see 👀 cognitive functions emerge from thousands of collaborating neurons in the brain 🧠 of a freely behaving mouse!
