1/4 Thrilled to be sharing new work published today in Nature describing the third wave of results from the PGC Cross-Disorder Group. This reflects a massive group effort to examine shared and unique genetic signal across >1 million cases for 14 psychiatric disorders. www.nature.com/articles/s41...

Mapping the genetic landscape across 14 psychiatric disorders - Nature

Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders...

nature.com

In 2018, Charles Murray challenged me to a bet: "We will understand IQ genetically—I think most of the picture will have been filled in by 2025—there will still be blanks—but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.

Your Genes Are Simply Not Enough to Explain How Smart You Are

Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.

theatlantic.com

My Dobzhansky lecture at BGA: "Theodosius Dobzhansky and the Origins of Radical Behavior Genetics" is publicly available. I talk about the tensions introduced into the field at the difficult border between science using model organisms and human beings. Thanks to BGA for the opportunity.

Sat_208_Dobzhansky_Lecture

Dobzhansky Lecture by Eric Turkheimer

vimeo.com

New blog post: The New Eugenics Companies (Oops, I meant to say generational health and embryo selection)

The New Eugenics Companies

Oops, I meant to say generational health and embryo selection

ericturkheimer.substack.com

It makes me wonder How all faces can be of approximate proportion But a billion variations. The same could also be for thoughts and feelings. identical matter; varying mind. The former is acknowledged. The latter? Hardly appreciated.

You've heard of DNA, but what about GNA? Very excited about this preprint with @jgthorp.bsky.social and others that introduces Genomic Network Analysis (GNA), an open-source multivariate tool for performing network analysis using GWAS summary statistics as input. 1/2 www.medrxiv.org/content/10.1...

Genomic network analysis characterizes genetic architecture and identifies trait-specific biology

Pervasive genetic overlap across human complex traits necessitates developing multivariate methods that can parse pleiotropic and trait-specific genetic signals. Here, we introduce Genomic Network Ana...

medrxiv.org

Thanks so much for hosting me and for the insightful questions @camerontellis.bsky.social! Looking forward to an in-person visit to share our recent extensions of this research line

Cameron Ellis@camerontellis.bsky.social · last yr.

Last week we were wow'd by @jacob-prince.bsky.social who presented his incisive and compelling work on the emergence of category selectivity in computational models. Check out the paper here (www.science.org/doi/pdf/10.1...) and keep an eye out for this rising star!

The BGA meeting in Atlanta will now have a hybrid option! 🌍🎥 We've also reopened abstract submissions for 2 weeks, with a hard deadline of March 14, 2025. Join us in person or virtually for a fantastic meeting! Register here: auth.oxfordabstracts.com?redirect=/st... #BGA2025

What happens when we break down DSM diagnoses into their individual symptoms and rebuild our classification system from the ground up? Do we see familiar DSM constructs, HiTOP dimensions, or something else entirely? New paper out today in CPS! ✨ journals.sagepub.com/doi/10.1177/... 1/🧵

Reconstructing Psychopathology: A Data-Driven Reorganization of the Symptoms in the Diagnostic and Statistical Manual of Mental Disorders - Miriam K. Forbes, Andrew Baillie, Philip J. Batterham, Aliso...

In this study, we reduced the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) to its constituent symptoms and reorganized the...

journals.sagepub.com

Miri Forbes@miriforbes.bsky.social · 3y ago

How do your favorite disorders fare in a data-driven reorganization of the DSM-5? Find out in this new preprint where we followed the patterns in 14,762 individuals’ symptoms with the goal of overcoming limitations in both the DSM and @HiTOP_system @craiganthonyrs.bsky.social @aidangcw.bsky.social

Today, I’m proud to say, our new paper on assortative mating was published. This gives me a good oppurtunity to make my first post on bluesky. Here is the link: doi.org/10.1038/s414... , and here are our key findings 🧵:

Great job students and faculty of the International Statistical Genetics Workshop 2024 in Boulder, what an amazing week it was, as always 🧬❤️🍻 Next year it's GWAS and sequence data analysis again, see you then: colorado.edu/ibg/workshop

Yesterday I taught my first lecture at the International Statistical Genetics Workshop (on gene-environment correlation). I'm very grateful to be part of this group!

Leaving the international statistical genetics workshop in Boulder tired, satisfied, impressed by the students, proud of the new faculty and filled with ideas on how to make the workshop even better.