In schistosome 🪱-endemic areas, people are repeatedly reinfected — but we still don’t fully understand how T cell responses develop in these cycles. In my first ever last-author paper (😱) we investigate this, comparing endemic and repeat controlled human schistosome infection: rdcu.be/exH58

T cell responses in repeated controlled human schistosome infection compared to natural exposure

Nature Communications - In schistosomiasis-endemic regions, the cyclical nature of infection and treatment complicates understanding of host immune responses. Repeated controlled human Schistosoma...

rdcu.be

[1/7] How close are we to a schistosomiasis vaccine? With help from an #MSCA fellowship and support from Batavia Biosciences, I spent 6 months reviewing 100+ pre-clinical studies on S. mansoni vaccines. Here's what we found: 📄 doi.org/10.1371/jour...

Pre-clinical studies of Schistosoma mansoni vaccines: A scoping review

Author summary Schistosomiasis, a major neglected tropical disease, is caused by infection with parasitic worms of the Schistosoma species, including Schistosoma mansoni. Individuals can be repeatedly...

doi.org

FIRST POST! Fungi drive asthma, but does this require germination? We show A. fumigatus spores activate DCs after 3hrs of swelling, promoting airway allergy. Antifungal itraconazole limits swelling & reduces allergic inflammation. Check it out: doi.org/10.1016/j.ja... @drpetercook.bsky.social 👩‍🔬

First 🦋 post (great to join everyone here) about our paper that's been published in JACI: www.jacionline.org/article/S009... Check it out if you have ever wondered how fungal spore growth controls how dendritic cells (clearly THE best immune cell) trigger inflammation that causes asthma...