Deep learning could help improve cortical visual prostheses - Michael Herzog’s lab in the @epfl-brainmind.bsky.social found that a deep neural network–based strategy reduced the number of phosphenes needed for object recognition, especially at low electrode densities: doi.org/10.1088/1741...
EPFL Brain Mind Institute
@epfl-brainmind.bsky.social
EPFL Brain Mind Institute researchers develop & deploy technology to gain fundamental insight into brain & spinal cord systems, exploiting this knowledge for new therapies for brain disorders & towards novel intelligent machines https://go.epfl.ch/brain
CRISPR HDR genome editing uses a repair template. But the @mccabelab.org in @epfl-brainmind.bsky.social found these templates sneak into the #Drosophila genome uninvited, corrupting downstream results. Their fix is a template design that makes stray insertions easy to catch: doi.org/10.1371/jour...
Why are some of us more willing to put in more effort & what changes when that fades? The Sandi @carmensandi10.bsky.social lab links effort-based motivation to mitochondrial health in D1 ventral striatum neurons. Males & females have the same deficit but via distinct routes: doi.org/10.1073/pnas...
How does the brain know when a sensation should trigger an action? Ghaderi, Crochet & Petersen in the @epfl-brainmind.bsky.social find that whisker secondary motor cortex (wM2) is where context meets touch, predicting a mouse's lick within 30 ms of a whisker deflection: doi.org/10.1038/s414...
Congratulations to Gioele La Manno @gioelelamanno.bsky.social upon receiving the the 2026 Boehringer Ingelheim Research Award at #FENS.
Congratulations to Carmen Sandi @carmensandi10.bsky.social upon receiving the 2026 Chica and Heinz Schaller Foundation Award today at #FENS.
Your eyes constantly move to hunt for information, a strategy known as infotaxis. New work from Prof. Mackenzie Mathis's lab @trackingactions.bsky.social shows mice do it too: in a VR task, they actively sought out the most informative views, adjusting as visual info changed doi.org/10.1016/j.cu...
The same touch can mean different things. New work from Carl Petersen's lab in the @epfl-brainmind.bsky.social mapped the cortical circuits underlying this in mice and found a surprise; the retrosplenial cortex was the first area to tell contexts apart after a whisker touch doi.org/10.7554/eLif...
Do good vision test scores predict better performance on other vision tests? A new study by the @epfl-brainmind.bsky.social group of Michael Herzog says: not really. Weak correlations across tests suggest we may be measuring methods, not vision itself. Read more: doi.org/10.1016/j.is...
Minis, aka spontaneous synaptic neurotransmitter vesicle release, was long dismissed as noise. Our new 📄 using optical electrophysiology shows minis are not spontaneous at all. They're an independent release modality regulated by Unc-5 & critical for synapse preservation 👉 doi.org/10.64898/202...
Honored to share that I’ve been promoted to Associate Professor with tenure at @epfl-brainmind.bsky.social @epfl-ai-center.bsky.social (EPFL)! 🎉 Deeply grateful to my current and past incredible lab members, collaborators, and mentors who’ve made this journey possible. 🧠✨🙏🏼
Electrophysiological recording feature extraction is hard to standardise. Prof. Henry Markram's @epfl-brainmind.bsky.social lab introduces eFEL: an open-source, cross-platform library defining 90+ electrophysiological features for efficient, reproducible, FAIR analysis: doi.org/10.1093/bioi...
eFEL: Electrophysiology Feature Extraction Library
AbstractMotivation. Electrophysiological recordings are essential in experimental and computational neuroscience, providing insights into neuronal excitabi
doi.org
New CmeCUT&Tag method from the lab of Fides Zenk @epign.bsky.social in @epfl-brainmind.bsky.social maps DNA methylation genome-wide both faster & cheaper. Validated across stem cells, organoids & tumours, its matches the gold standard of bisulfite sequencing doi.org/10.1038/s414...
Congratulations to @epfl-brainmind.bsky.social professors Mackenzie Weygandt Mathis @trackingactions.bsky.social and Alexander Mathis @trackingskills.bsky.social on their well-deserved promotion to Associate Professor! actu.epfl.ch/news/appoint...
I‘m looking for postdoc candidates in computer vision and control theory (2 positions). Get in touch if you’re interested.
Can microglia be stimulated to help fight #Alzheimer’s disease (AD)? New work from the Gräff @graeffjohannes.bsky.social & Sanchez-Mut groups shows PM20D1, via its metabolite OLE, promotes microglial engagement with amyloid plaques and neuroprotection in AD models - doi.org/10.1038/s413...
New work by Simone Astori in Carmen Sandi's @carmensandi10.bsky.social lab shows that nucleus accumbens medium spiny neurons rapidly tune their excitability to mitochondrial energy shifts via K-ATP channels, linking neuronal bioenergetics to effort-related motivated behaviour doi.org/10.1038/s413...
Many motor tasks require precise coordination between multiple motor & sensory systems. New #Drosophila work by the @epfl-brainmind.bsky.social group of Pavan Ramdya reveals the centralized neural circuits necessary to solve antennal grooming synchronized motor-control - doi.org/10.1038/s414...
🧠 Carmen Sandi | Chica and Heinz Schaller Foundation Award Lecture 🌟 At #FENS2026, join Prof. Carmen Sandi, École Polytechnique Fédérale de Lausanne, on 9 July! 🔗 Meet all the speakers: buff.ly/1EBdiLL
Carl Petersen: Cortical circuits for whisker sensory perception—From barrel columns to brain-wide interactions doi.org/10.1016/j.co...
Two new @epfl-brainmind.bsky.social group reviews: The lab of Alexander Mathis @trackingskills.bsky.social: The behavior biopsy: Interpreting animal behavior as embodied, situated, and hierarchical doi.org/10.1016/j.co...
Many congratulations to @epfl-brainmind.bsky.social professor Gioele La Manno @gioelelamanno.bsky.social!
🎉 Congratulations to the winner of the Boehringer Ingelheim FENS Research Award 2026! #FENS is proud to announce that Gioele La Manno has been awarded the Boehringer Ingelheim FENS Research Award 2026 in recognition of his outstanding scientific achievements. 🧠 🔬 👉 buff.ly/N0lEeUI
Novelty is not just about whats new, but also what feels new given past experience. New study from Sophia Becker in Wulfram Gerstner’s @epfl-brainmind.bsky.social lab posits a model showing how similarity between familiar and novel stimuli shapes exploration and learning - doi.org/10.1016/j.ne...
How does circuit structure shape neural activity? The lab of @epfl-brainmind.bsky.social Prof. Wulfram Gerstner shows that distinct neural circuits can produce similar low-dimensional dynamics, while retaining clear signatures in single neuron and population activity data: doi.org/10.1016/j.ne...
What if memory loss from aging or disease could be restored? The lab of @epfl-brainmind.bsky.social Professor Johannes Gräff @graeffjohannes.bsky.social shows that partial cellular reprogramming of engram neurons restores learning and memory to youthful levels in mice - doi.org/10.1016/j.ne...
When objects are close together, seeing details is harder 👉visual crowding. @epfl-brainmind.bsky.social prof. Michael Herzog's lab shows that a single nearby object barely affects perception, but many can aid or impede it, depending on alignment, challenging current theories doi.org/10.1177/1747...
Understanding how brain regions communicate to shape behavior requires realistic models. The @epfl-brainmind.bsky.social labs of Carl Petersen & Wulfram Gerstner show that adding biological features to neural networks improves the prediction of brain responses to stimulation doi.org/10.7554/eLif...
Identifying individual wild animals is key for conservation. The lab of @epfl-brainmind.bsky.social professor Alexander Mathis @trackingskills.bsky.social uses AI and images of Alaskan brown bears to non-invasively identify individuals & their behavior across seasons & years doi.org/10.1016/j.cu...
EPFL ELISIR apps now open go.epfl.ch/ELISIR. Fantastic opportunity for young neuroscientists to start an independent lab right after PhD, just like @epfl-brainmind.bsky.social ELISIR group leaders @jamespriestley.bsky.social & @ashleymaynard.bsky.social. www.youtube.com/watch?v=qjPD... 👉 April 1 26
EPFL Life Sciences Early Independent Research Scholar (ELISIR)
From exceptional PhD directly to independent group leader
go.epfl.ch
@epfl-brainmind.bsky.social professor Michael Herzog's lab carried out a simulation study to identify how many visual elements are needed for object recognition by cortical visual prostheses, establishing a practical lower-bound phosphene estimate for more effective function: doi.org/10.1016/j.vi...