Nominations for the 2027 New Voices in Infection and Immunity cohort are now open: asm.org/NewVoices-IA...
Fabian Rivera-Chávez
@fabianrchavez.bsky.social
Assistant Professor in the Departments of Pediatrics & Molecular Biology at UC San Diego. Interested in host-microbe biology, bacterial toxins, and metabolism.
1/ Excited to share a new preprint! My PhD student Claire asked why neonatal mice become resistant to experimental cholera as they age. Turns out, early-life acquisition of maternally transmitted lactobacilli helps protect against experimental cholera www.biorxiv.org/content/10.6...
Early-life acquisition of Lactobacillaceae protects against experimental cholera
Cholera causes severe diarrheal illness in young children, but the mechanisms underlying age-dependent susceptibility remain unclear. Experimental cholera in neonatal mice recapitulates age-dependent ...
biorxiv.org
Now published in Cell Reports! @cellpress.bsky.social www.cell.com/cell-reports... My postdoc Dr. Maria de la Paz Gutierrez led this work showing that cholera toxin drives epithelial L-lactate production in the small intestine, creating a nutrient that Vibrio cholerae exploits during disease
Cholera-toxin-induced disease generates epithelial-cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine
Gutierrez et al. show that cholera toxin induces epithelial LDHA-dependent L-lactate production in the small intestine, creating a nutrient niche that Vibrio cholerae exploits through LldD-mediated L-...
cell.com
1/ Excited to share the first preprint from my lab! 🎉 My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut. Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease
Congratulations to my first PhD student, Dr. Claire Chapman, on successfully defending her PhD! Stay tuned for an exciting story about the role of the small intestinal microbiota in susceptibility to cholera! #ProudPI
🌟 Applications are accepted for UC San Diego RAPID program's 2026-27 cohort. This highly-rated and effective #FacultyDevelopment opportunity is for junior faculty researchers in #InfectiousDiseases. 👉 Learn more and apply today at rapid.ucsd.edu. ⏰ Deadline: Sunday, March 1 #UCSD_RAPID
Important and timely read in the New England Journal of Medicine: Twelve former commissioners of the FDA express concern that the agency’s recent moves will undermine a regulatory model designed to ensure vaccine safety, effectiveness, and availability.
A Threat to Evidence-Based Vaccine Policy and Public Health Security at the FDA | NEJM
Twelve former commissioners of the FDA express concern that the agency’s recent moves will undermine a regulatory model designed to ensure vaccine safety, effectiveness, and availability.
nejm.org
Applications for UC San Diego RAPID program's 2026-27 cohort are now open! This highly-rated and effective career development opportunity is for junior faculty researchers in #InfectiousDiseases. Learn more and apply today at rapid.ucsd.edu! #UCSD_RAPID #FacultyDevelopment
What do I love the most about UCSD? My amazing colleagues. Congratulations @chulab.bsky.social and @alistairrussell.bsky.social on your promotion and to Kees Murre for being elected to the NAS!
Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.
Commensal yeast promotes Salmonella Typhimurium virulence - Nature
Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.
nature.com
1/ Excited to share the first preprint from my lab! 🎉 My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut. Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease
Cholera toxin-induced disease generates epithelial cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine
Cholera toxin (CT) promotes Vibrio cholerae colonization by altering gut metabolism to favor pathogen growth. We have previously found that CT-induced disease leads to increased concentrations of L-la...
biorxiv.org
Saddened to learn of the passing of Moselio "Elio" Schaechter—Distinguished Professor at Tufts, SDSU and UCSD—humanist and visionary leader in the fields of microbiology and scientific communication—mentor, friend, and inspiration to me and so many others Small Things Considered Big Things Achieved
The Raffatellu, Chu @chulab.bsky.social Rivera-Chavez @fabianrchavez.bsky.social labs were well represented at the #standupforscience @standupforscience.bsky.social event at #UCSD today!
Microbiome science needs more microbiologists- A new commentary authored by myself and @abaumler.bsky.social www.nature.com/articles/s41...
Microbiome science needs more microbiologists - Nature Microbiology
Microbiome science is a multi-disciplinary field, but classical microbiologists are needed to ensure advances are grounded in our understanding of basic microbiological concepts.
nature.com
Can classical microbiology transform microbiome research? 🤔 Our new article explores how integrating microbiological concepts can build a stronger theoretical framework for microbiome sciences. 🌟 Read more about the path to hypothesis-driven research:
Microbiome science needs more microbiologists- A new commentary authored by myself and @abaumler.bsky.social www.nature.com/articles/s41...
All brought to you by the good people at OMICS International who own and operate“more than 500 peer-reviewed journals” So do I (A) just ignore this? (B) do something? If you chose the latter, what do you suggest I do? Any replies with some guidance or cynical humor welcome
Academic Skyers: I am compiling a list of policies and statements from various universities about how they are handling the "pause" in terms of stopping expenditures (or not). Please respond to this post with your institution and materials. THANK YOU!
We are lookkng for a behavioral neurologist to join us at Stanford in sunny California! Feel free to reach out to me with any questions! 🌞😊🧠
The Division of Memory in the Department of Neurology at Stanford University seeks a board-certified neurologist with training in behavioral neurology or equivalent to join the Department. #StanfordJobs #Neurology facultypositions.stanford.edu/cw/en-us/job...
Beautiful paper from the Elizabeth Winzeler laboratory at UC San Diego out today in Science building a predictive model of malaria drug resistance by analyzing the genomes of 724 parasite genomes evolved in the lab to resist one of 118 different antimalarial compounds today.ucsd.edu/story/a-new-...
A New Approach to Predicting Malaria Drug Resistance
Researchers at UC San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance.
today.ucsd.edu
An updated list with those added who wanted to join go.bsky.app/VVLoMPx
Nothing is better than your past trainees successes
Believe it or not, GRC has told me we need more registered applicants or this meeting might not survive! Please don't let that happen if you can afford to attend 🙏
If you're interested in learning about the latest of fundamental mycobacteriology, sign up for #GRCMyco2025! Acceptances will start in September, check out the full program and please RT!
This will me my fist blueet! Microbial N-Acyl lipids have been shown to regulate glucose, pain etc among other things. Therefore Helena, Vincent and Martijn asked the question - are there more and if so what types? And boy did they find some www.biorxiv.org/content/10.1...
The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds
N -acyl lipids are important mediators of several biological processes including immune function and stress response. To enhance the detection of N -acyl lipids with untargeted mass spectrometry-based...
biorxiv.org
What I said Jan 2022... So if we all agree that we will be living with respiratory viruses in the future & that they have an airborne transmission component, can we agree that it is essential to clean indoor air using filtration & ventilation for all schools/businesses so we can get our lives back?
Hi everyone, this is my first post here and it’s great to get so many new connections. My lab works on host-pathogen interaction, particularly in the context of Salmonella infection, mucosal immunity, microbiota-host interaction, microbial competition. We are a fun, diverse, enthusiastic group.
BlueSky I really need you to stick this landing.
Hiiii Fun facts in no particular order: I’m a NIH-funded physician scientist 👩🔬 study pregnancy/stress/microbiome 🦠 help direct the OSU MSTP 👩🎓 Direct the OSU Soter Women’s Health Research Program 🚺 Have 4 kids 👯👯♀️ Married to the worlds tallest gynecologist! ™️
CMIC/SIMB registration is now open www.simbhq.org/cmic/attend/ For people interested in presenting, contributed submissions is August 30, 2024.