Fabian Rivera-Chávez

@fabianrchavez.bsky.social

Assistant Professor in the Departments of Pediatrics & Molecular Biology at UC San Diego. Interested in host-microbe biology, bacterial toxins, and metabolism.

1/ Excited to share a new preprint! My PhD student Claire asked why neonatal mice become resistant to experimental cholera as they age. Turns out, early-life acquisition of maternally transmitted lactobacilli helps protect against experimental cholera www.biorxiv.org/content/10.6...

Early-life acquisition of Lactobacillaceae protects against experimental cholera

Cholera causes severe diarrheal illness in young children, but the mechanisms underlying age-dependent susceptibility remain unclear. Experimental cholera in neonatal mice recapitulates age-dependent ...

biorxiv.org

Important and timely read in the New England Journal of Medicine: Twelve former commissioners of the FDA express concern that the agency’s recent moves will undermine a regulatory model designed to ensure vaccine safety, effectiveness, and availability.

A Threat to Evidence-Based Vaccine Policy and Public Health Security at the FDA | NEJM

Twelve former commissioners of the FDA express concern that the agency’s recent moves will undermine a regulatory model designed to ensure vaccine safety, effectiveness, and availability.

nejm.org

Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.

Commensal yeast promotes Salmonella Typhimurium virulence - Nature

Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.

nature.com

1/ Excited to share the first preprint from my lab! 🎉 My postdoc Paz asked how cholera toxin (CT) helps Vibrio cholerae thrive in the gut. Turns out, CT rewires epithelial metabolism toward L-lactate production—fueling pathogen growth in the small intestine during disease

Cholera toxin-induced disease generates epithelial cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine

Cholera toxin (CT) promotes Vibrio cholerae colonization by altering gut metabolism to favor pathogen growth. We have previously found that CT-induced disease leads to increased concentrations of L-la...

biorxiv.org

Saddened to learn of the passing of Moselio "Elio" Schaechter—Distinguished Professor at Tufts, SDSU and UCSD—humanist and visionary leader in the fields of microbiology and scientific communication—mentor, friend, and inspiration to me and so many others Small Things Considered Big Things Achieved

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Can classical microbiology transform microbiome research? 🤔 Our new article explores how integrating microbiological concepts can build a stronger theoretical framework for microbiome sciences. 🌟 Read more about the path to hypothesis-driven research:

Lauren Radlinski@laurenradlinski.bsky.social · 2y ago

Microbiome science needs more microbiologists- A new commentary authored by myself and @abaumler.bsky.social www.nature.com/articles/s41...

All brought to you by the good people at OMICS International who own and operate“more than 500 peer-reviewed journals” So do I (A) just ignore this? (B) do something? If you chose the latter, what do you suggest I do? Any replies with some guidance or cynical humor welcome

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Academic Skyers: I am compiling a list of policies and statements from various universities about how they are handling the "pause" in terms of stopping expenditures (or not). Please respond to this post with your institution and materials. THANK YOU!

Beautiful paper from the Elizabeth Winzeler laboratory at UC San Diego out today in Science building a predictive model of malaria drug resistance by analyzing the genomes of 724 parasite genomes evolved in the lab to resist one of 118 different antimalarial compounds today.ucsd.edu/story/a-new-...

A New Approach to Predicting Malaria Drug Resistance

Researchers at UC San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance.

today.ucsd.edu

What I said Jan 2022... So if we all agree that we will be living with respiratory viruses in the future & that they have an airborne transmission component, can we agree that it is essential to clean indoor air using filtration & ventilation for all schools/businesses so we can get our lives back?

Hi everyone, this is my first post here and it’s great to get so many new connections. My lab works on host-pathogen interaction, particularly in the context of Salmonella infection, mucosal immunity, microbiota-host interaction, microbial competition. We are a fun, diverse, enthusiastic group.

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Hiiii Fun facts in no particular order: I’m a NIH-funded physician scientist 👩‍🔬 study pregnancy/stress/microbiome 🦠 help direct the OSU MSTP 👩‍🎓 Direct the OSU Soter Women’s Health Research Program 🚺 Have 4 kids 👯👯‍♀️ Married to the worlds tallest gynecologist! ™️