Last week I have defended my PhD in the beautiful Aula of the @rug.nl with a thesis entitled "Mapping the Sequence Landscape of an Artificial Enzyme". Such a huge diploma is proportionate to the immensely beautiful experience behind a PhD in the @roelfesgroup.bsky.social. Thank you very much to all!

Merck is accepting applications for its 2026 Future Talent Program - these are internships and co-ops in a variety of areas including drug discovery, vaccines, clinical trials, biostatistics, epidemiology, HEOR, data science, regulatory affairs, and more #chemsky 🧪⚗️ jobs.merck.com/us/en/search...

Hi Bluesky! 🦋 We are the Aesthetics and Learning Lab (ALL). ALLab is based in the Leibniz-Institut für Wissensmedien (IWM) in Tübingen. Its aim is to empirically investigate how and what can be learned from aesthetic experiences ✨ Stay tuned, for now... That's ALL folks!

📢📢 New paper out! AI and networks can be used to predict distal mutations in proteins, even in artificial enzymes! Check out the article here ----‐> doi.org/10.1016/j.ij... Thread 1/5 🧵

📢 New publication alert 📢 🧪Studying enzyme conformational dynamics always hides new surprises, especially when you discover that beneficial mutations destabilize the enzyme! Read more here ---> doi.org/10.1002/cbic... Thread 🧵 1/5

📢📢📢 PhD Opportunity! Join our research group at RUG! We're seeking a motivated PhD student for a project on biocatalytic cascade processes combining natural and designer enzymes, supported by machine learning. Click below to learn more — and feel free to share! sites.google.com/rug.nl/roelf...

Roelfes group - Open Positions

PhD position on Hybrid biocatalytic cascades aided by Machine learning (1.0 FTE)

sites.google.com

Our latest publication is out in @angewandtechemie.bsky.social! We generated and engineered a novel artificial metalloenzyme for the enantioselective synthesis of a panel of γ-nitro-carbonyl compounds on a preparative scale.

Season's greetings from Roelfes and Mayer groups! Wishing our colleagues, collaborators, and the entire community a joyful holiday season and a prosperous New Year ahead! 🎉🎄✨🧪

Two days of very interesting talks at #NWOChains24, big thanks to everyone that stopped by my poster for the stimulating exchange of ideas. Happy to have won the poster prize! 🏆🏆

Now I can share external links without the posts being down regulated - I thought it would share this again!:) I have compiled a list of now 100+ companies in the 'TechBio' space into a fully open database for the community. Find here and please share if you like open.substack.com/pub/harrisbi...