Fendt Lab
@fendtlab.bsky.social
Cancer Research | Metastasis Biology | Cellular Metabolism
New liver-specific mechanism of immune evasion: Palmitate promotes via DHHC17 laminin-511 secretion, which disables the antitumor function of neutrophils & supports liver metastasis. Big congratulations to Anke Vandekeere and all co-authors! 🎉 bit.ly/4yXHVap #Metastasis #Immunology #FWO #KOTK
Nature research paper: Steatosis shapes prognosis-defining liver metastasis heterogeneity in CRC go.nature.com/4b5VNoN
Steatosis shapes prognosis-defining liver metastasis heterogeneity in CRC - Nature
Liver steatosis increases formation of replacement liver metastases by increasing MYC stability through acetylation, which increases proline synthesis and collagen production.
go.nature.com
New paper alert rdcu.be/frxGx 🚀 Fatty liver disease is more than a metabolic condition, it can actively drive the development of poor prognosis colorectal cancer liver metastasis heterogeneity. Big congratulations to Yiming Peng-Winkler and everyone involved! #FWO #VIB
With a new statement, @scienceeurope.org and its Member Organisations call all co-legislatorsfor the careful reconsideration of the overall policy direction taken in the current FP10 negotiations towards European Partnerships, to preserve the value of this key instrument scieur.org/fp10-partner...
Position Statement: Preserving Key Values of European Partnerships in FP10
scieur.org
Please share this gift article from The New York Times with friends, family, sceptics, and People who think that studying weird things is a waste of money. Then follow up with meaningful discussion about what I call 'free range science'. Free without subscription. www.nytimes.com/2026/06/20/o...
Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack
nytimes.com
Fantastic talks by Dr. Maria Caliz Molina and Dr. Yiming Peng-Winkler at the annual Liver Metastasis Research Network (LMRN) conference.
We have a new PhD in the lab! Big congratulations to Dr. Vandekeere @ankevandekeere.bsky.social! All the best for your postdoc research at the lab of @martinguilliams.bsky.social
@fendtlab.bsky.social postdoc Sebastian Igelmann shares his highlights and experiences from the EACR Tumor Ecosystem conference!
EACR - European Association for Cancer Research@helloeacr.bsky.social · 3mo agoEACR Travel Grant winners share their reflections on attending the most recent edition of our cutting-edge The Tumour Ecosystem conference, including what they learned and how the experience supported their research journey. Read the full article here: magazine.eacr.org/eacr-travel-...
After a huge researcher backlash, the European Research Council has reversed a policy it introduced to help deal with a deluge of applications to its coveted awards. go.nature.com/428LA6d
Prestigious European science funder scraps stricter rules after researcher backlash
The tough new policy was introduced to curb submissions, but drew criticism from researchers.
go.nature.com
Hopefully the beginning of something bigger to ensure that European science prospers today and in the future!
Johanna Joyce@johannajoyce.bsky.social · 3mo agoNew piece on the decision of #ERC to reverse their stricter rules after the community came together to voice our opinions - a great example of the power of collective action! Very happy to have been part of this - and to see how we can now build on this momentum 🙌 www.nature.com/articles/d41... 🧪
After collective feedback from the research community, the ERC decided to keep the existing resubmission rules for 2027. A reminder that speaking together matters - and that continued advocacy for strong research and funding in Europe is essential. Grateful to everyone who contributed. #ERC 🇪🇺
Fendt Lab@fendtlab.bsky.social · 3mo agoIn <3 days, our open letter gathered 1,000+ signatures from 36 countries and 200+ institutions reflecting broad concern about restricting ERC applications & strong support for the proposed alternatives + the ERC mission to fund innovative research now and in the future. 🇪🇺 #ERC
I argued that when a grant rejection can hinge on something small, and you then have to wait years to resubmit, the cost becomes so high that instead of suggesting “high-risk high-gain” plans scientists will prepare more cautious, less ambitious proposals (2/3)
Abrupt change to European funder’s rules leaves researchers shut out
Flood of proposals to European Research Council—perhaps unleashed by AI—means unsuccessful applicants must wait longer to reapply
science.org
In <3 days, our open letter gathered 1,000+ signatures from 36 countries and 200+ institutions reflecting broad concern about restricting ERC applications & strong support for the proposed alternatives + the ERC mission to fund innovative research now and in the future. 🇪🇺 #ERC
Johanna Joyce@johannajoyce.bsky.social · 4mo agoWhat should Europe do when demand for #ERC funding keeps rising? Restrict access or invest in excellence? Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness Consider to share & sign - see below 🧪
What should Europe do when demand for #ERC funding keeps rising? Restrict access or invest in excellence? Please read our open letter calling for reconsideration of the ERC 2027 resubmission restrictions & for constructive alternatives that preserve openness Consider to share & sign - see below 🧪
#erc | Johanna Joyce
What should Europe do when demand for its most successful frontier research programme keeps rising? Restrict access, or invest in the excellence it has created? A new open letter, spearheaded by Sara...
linkedin.com
Great short talk and discussion by Dr Sebastian Igelmann at the @helloeacr.bsky.social Tumor Ecosystem Conference and many thanks to EACR-WCR @worldwidecancer.bsky.social who sponsored the travel grant Sebastian received!
Where do the lipids come from & how do lung metastases benefit from them? Congratulations Dr Xiao-Zheng Liu @teenyl.bsky.social & Dr Ming Liu! Amazing collaboration with Prof. Yuneva and Prof. Altea-Manzano @alteamanzanolab.bsky.social Read more bit.ly/4lBSN7N @wcrf.org @fwovlaanderen.bsky.social
Opening celebration for the Methusalem consortium Fendt, Scheele, Desmedt. We are looking forward to making PROGRESS in intercepting breast cancer in the context of patient physiology! @kuleuvenuniversity.bsky.social
The Fendt Lab wishes you happy holidays and a prosperous 2026! May there be many discoveries, collaborations and miracles 💫
I am thrilled and deeply honored to have been selected as a KU Leuven Leading Researcher (Methusalem beneficiary). Together with Colinda Scheele & Christine Desmedt, we will dissect breast cancer and its progression to uncover fundamental mechanisms and translate them into impact for patients.
Dr. Xiao-Zheng Liu has been awarded the 2025 Beug Metastasis Research Prize! Big congratulations to this amazing recognition! @embo.org @fwovlaanderen.bsky.social www.beugstiftung-metastase.de/events/
How does our diet influence breast cancer progress & why is fundamental research important? We discussed this topic and showcased mass spectrometry imaging to a broad audience on the Day of Science! Many thanks to everyone who was involved! @wcrf.org @fwovlaanderen.bsky.social @vib-ccb.bsky.social
We have a new PhD in the lab! Big congratulations to Dr. Ming Liu to a fantastic PhD defense!
Honored to be part of the highly cited researchers. This is a big recognition for my team and our research. Together we continue to work towards a future where cancer is less deadly! @fwovlaanderen.bsky.social @wcrf.org
Chris Marine Lab@marinelab.bsky.social · 9mo ago
Why fundamental research is fundamental to progress, seeding major breakthroughs Editorial @nature.com this week And 7 basic science discoveries that changed the world nature.com/articles/d41... nature.com/articles/d41...
Big congratulations to Margherita Demicco for giving an excellent short talk & Sebastian Igelmann for winning the poster prize at the BACR Annual Meeting 2025! @embo.org @fwovlaanderen.bsky.social @viblifesciences.bsky.social
We study cancer progression and metastasis. Today wearing the 🎗️ we would like to thank all collaborators, patients & their families, and funders because together we are working towards a future where cancer is less life threatening than today! @fwovlaanderen.bsky.social #STK #KOTK @wcrf.org
It was a great opportunity to present my study in the conference, and really appreciate all the fantastic questions and discussions. Many thanks to @dmmjournal.bsky.social for the travel grant and @embo.org @fwovlaanderen.bsky.social support.
Fendt Lab@fendtlab.bsky.social · 10mo agoBig congratulations to Dr. Xiao-Zheng Liu for giving an excellent short talk at the #6thCancer&Metabolism meeting at the Palais des Congrès, La Grande Motte, France funded by a @dmmjournal.bsky.social travel grant. @embo.org @fwovlaanderen.bsky.social
Big congratulations to Dr. Xiao-Zheng Liu for giving an excellent short talk at the #6thCancer&Metabolism meeting at the Palais des Congrès, La Grande Motte, France funded by a @dmmjournal.bsky.social travel grant. @embo.org @fwovlaanderen.bsky.social
