Today, at University of Helsinki RPU Science day, our researchers Stefan Mutter and Emma Dahlström presented their findings on ”Proteomics in type 1 diabetes and kidney disease”. Congrats on the successful presentation 🤩👏

Nadja Vuori presented her latest poster, "Survival GWAS Meta-Analysis Identifies Novel Genetic Loci for Severe Diabetic Retinopathy in Type 1 Diabetes" offering critical new insights into the genetic risk loci of severe diabetic retinopathy. Congratulations on a fantastic presentation!

New #FinnDiane publication. Chronic low-grade inflammation adds to the coronary artery disease risk from metabolic syndrome in type 1 diabetes, but only in those WITHOUT DKD. Managing metabolic risk factors early and screening for chronic low-grade inflammation offer improved risk stratification.

New findings from the FinnDiane study: central obesity in type 1 diabetes matters. Even a 0.1-unit increase in waist-to-height ratio was associated with a 21% higher risk of coronary artery disease, and the association was most pronounced among those without kidney disease. doi.org/10.2337/dc25...

Waist-to-Height Ratio Is Associated With the Risk of Coronary Artery Disease in Type 1 Diabetes: A 19-Year Cohort Study

Obesity, kidney disease, and coronary artery disease (CAD) are interconnected. Here, the relationship between central obesity and CAD across albuminuria ca

doi.org

New study! Our study is the first study to test whether early OCTA‑detected retinal microvascular changes relate to cognition in middle‑aged adults with T1D. We found that larger retinal abnormalities were linked to poorer working memory. www.clinicalkey.com#!/content/pl...

ClinicalKey

clinicalkey.com

In middle-aged individuals with T1D, cerebral microbleeds were related to a subtle, yet systematic impairment in cognition. Results provide insight into the development of early cerebral small vessel disease-related cognitive changes already in midlife. www.sciencedirect.com/science/arti...

Cerebral microbleeds are associated with deficits in cognitive processing speed and executive functions in middle-aged adults with type 1 diabetes

Adults with type 1 diabetes (T1D) have an increased risk of cerebral small vessel disease (cSVD)-related brain changes already in midlife, yet their s…

sciencedirect.com

Individuals living with type 1 diabetes face a significantly elevated risk of myocardial infarction. A new study shows that the two main subtypes, STEMI and NSTEMI, behave differently over time. @finndiane.bsky.social research.folkhalsan.fi/news-article...

Myocardial infarction subtypes in type 1 diabetes follow different patterns and have different risk profiles

Individuals living with type 1 diabetes face a significantly elevated risk of myocardial infarction, but not all myocardial infarctions are alike. A new study shows that the two main subtypes, STEMI a...

research.folkhalsan.fi

New—Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation #myocardial #infarction in type 1 #diabetes in Finland: a nationwide cohort study www.thelancet.com/journals/lan... #T1D #MI #CVD #MedSky #EndoSky #CardioSky

Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation myocardial infarction in type 1 diabetes in Finland: a nationwide cohort study

We report that STEMI and NSTEMI exhibit different incidence patterns depending on age and year of myocardial infarction. STEMI and NSTEMI also differed regarding risk profiles, demonstrating that myoc...

thelancet.com

STEMI rates are falling in type 1 diabetes 📉 but NSTEMI rates are not📈 New data from the FinnDiane cohort show these two myocardial infarction subtypes have distinct risk profiles, with microvascular complications playing a key role in NSTEMI @helsinki.fi ➡️ www.thelancet.com/journals/lan...

Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation myocardial infarction in type 1 diabetes in Finland: a nationwide cohort study

We report that STEMI and NSTEMI exhibit different incidence patterns depending on age and year of myocardial infarction. STEMI and NSTEMI also differed regarding risk profiles, demonstrating that myoc...

thelancet.com

Our new #article on depression and adherence to cardioprotective medication in people with T1D is now published. Those prescribed cardioprotective therapy who had diagnosed depression or antidepressant purchases had higher odds of having poor rather than good adherence to cardioprotective therapy.

Huge congratiolations to Dr. Marika Eriksson for the second place in Finnish Diabetes Research Society's competition for the best thesis of the year! #ValtakunnallinenDiabetespaiva #diabetes #research

Today is #WorldDiabetesDay! The #FinnDiane Study highlights that reducing sitting at work can help people with #Type1Diabetes maintain cardiovascular health doi.org/10.1186/s129... Let’s make workplaces healthier for people with #diabetes: move more, sit less! #DiabetesAndTheWorkplace

Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study - Cardiovascular Diabetology

Background Sedentary behavior, such as excessive sitting, increases risk of cardiovascular disease and premature mortality in the general population, but this has not been assessed in type 1 diabetes....

doi.org

🌍✨Happy #WorldDiabetesDay! 💙 Today, we celebrate all people living with diabetes and the progress made in research, innovation and care 💪 Let’s continue to raise our voices, drive policy change and shape a future where no one is left behind. #WorldDiabetesDay #DiabetesAwarenessMonth

Our new #article on diabetic kidney disease has been published! Using exome-wide analysis, the GENIE consortium identified a novel rare EXD3 variant linked to the diabetic kidney disease in T1D. Full study: www.kireports.org/article/S246... @folkhalsanresearch.bsky.social #diabetes #kidney

Exome-Wide Analysis Identifies a Rare EXD3 Missense Variant Associated With Diabetic Kidney Disease

Diabetic kidney disease (DKD) is a major complication of diabetes, with genetic factors contributing to its progression. Although genome-wide association studies (GWAS) have identified common variants...

kireports.org

Excited to share our latest #article! We conducted the largest NGS study to date on SDR in type 1 diabetes, identifying rare variants in genes like AFAP1L1, SLC30A9, HPS3, PELI1 and CSMD2. 🔗 iovs.arvojournals.org/article.aspx... @folkhalsanresearch.bsky.social #FinnDiane #T1D #retinopathy #diabetes

Congratulations Anni, for successfully defending your doctoral dissertation! Full text available here: urn.fi/URN:ISBN:978... @finndiane.bsky.social @helsinki.fi

Huge congrats to Anni Antikainen on a successful doctoral defence! Electronic version of the dissertation can be found here: helda.helsinki.fi/items/e7745a... @folkhalsanresearch.bsky.social #diabetes #folkhälsan #doctoralresearch

Small panel of proteins can predict the onset and progression of diabetic kidney disease in type 1 diabetes as shown by Stefan Mutter #EASD2025 #proteomics

Raija Lithovius showed that key factors for rapid eGFR decline were largely similar across cohorts with different ethnic backgrounds but some differences exist and should be further investigated #EASD2025

Lifetime exposure to hyperglycemia and lipids are risk factors for heart failure in type 1 diabetes as presented by Rebecka Bergdal #EASD2025

Nadja Vuori found new genomic hits in her first-ever genome-wide association survival analysis in retinopathy and type 1 diabetes #EASD2025

Congratulations to Anniina Tynjälä for winning a best early career abstract at #EASD2025 for her work on the genetic background of arterial stiffness in type 1 diabetes

Krishna Adeshara presents our results with regards to genetics of protein glycation: genetic variants linked to advanced glycation end products were associated with higher risk of coronary artery disease in type 1 diabetes #EASD2025

Sara Itkonen showed that neuropathy is associated with the future strokes in type 1 diabetes in our cohort #EASD2025

Women with two or more children have fewer complications according to Kaarina Rimpeläinen who is presenting her results at the European Diabetes conference #EASD2025

Congratulations, Jani Haukka, for a successful doctoral defense! Electronic version of the dissertation: hdl.handle.net/10138/596743 @folkhalsanresearch.bsky.social #diabetes #research #folkhälsan

@niinasandholm.bsky.social expertly presenting her team’s multiomic research for #diabetes #kidney disease #DKD #GENIE @finndiane.bsky.social @qubelfastofficial.bsky.social #RenalResearchNI #UKKW25

Congratulations @emmadahlstrom.bsky.social for winning the #EDNSG Rising Star Award for her work towards establishing causal paths to diabetic kidney disease! @finndiane.bsky.social @folkhalsanresearch.bsky.social

Congratulations to FinnDiane researcher @emmadahlstrom.bsky.social for receiving the rising star Harry Keen award at the annual meeting of the EDNSG!

In our latest study, there was no connection between age at type 1 diabetes onset and intracranial volume, indicating that earlier diabetes onset does not have a clinically significant impact on brain growth doi.org/10.1186/s129... @folkhalsanresearch.bsky.social @helsinki.fi

Age at type 1 diabetes onset does not influence attained brain volume - BMC Endocrine Disorders

Introduction Type 1 diabetes is suspected to hamper brain growth, implying that people with earlier diabetes onset would, on average, achieve lower maximal brain volume. We set out to test this hypoth...

doi.org