Francois Lebreton
@flebreton.bsky.social
Director of bioinformatics at WRAIR-MRSN. Interests in microbial genomics, antimicrobial resistance and bacterial evolution.
Cumulative cgMLST : Our novel preprint is out @biorxiv doi.org/10.1101/2025...
Cumulative cgMLST provides increased discrimination of nested phylogenetic groups
Background Core genome multilocus sequence typing (cgMLST) is a powerful method for bacterial strain genotyping. However, the size of the core genome decreases as the phylogenetic breadth of the targe...
doi.org
New preprint out! Anjali Sapre, Melissa Martin and co. mapped the evolutionary routes of convergence in K pneumo. Pop analysis of >1,400 global genomes & 7,500 closed plasmids to see how #AMR & virulence genes come together and impact phenotypes. www.researchsquare.com/article/rs-8...
Preferred evolutionary routes of convergence in Klebsiella pneumoniae favor siderophore acquisition over hypervirulence
The rise of Klebsiella pneumoniae combining antimicrobial resistance and virulence genes poses a major health threat, but the evolutionary routes and phenotypic consequences of this convergence are po...
researchsquare.com
Please visit: www.icarecourse.org @ICARe_AMR has a great atmosphere and location @LesPensieres , with a unique faculty and a special session on #AMR #genomics with François Lebreton @flebreton.bsky.social and myself – great opportunities for networking and scientific discussions
New postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!
